Opportunity Information: Apply for RFA NS 17 002

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "High Impact Neuroscience Research Resource Grants (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
  • This funding opportunity was created on Sep 21, 2016.
  • Applicants must submit their applications by Feb 14, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA NS 17 002

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Opportunity Summary:

The High Impact Neuroscience Research Resource Grants (R24) funding opportunity (RFA-NS-17-002) is a National Institutes of Health program run through the Department of Health and Human Services, focused on supporting neuroscience research by expanding access to valuable shared resources. Rather than funding typical hypothesis-driven research projects, this program is meant to build, scale, distribute, and broadly disseminate resources that many neuroscience investigators can use. The emphasis is on high-impact efforts that remove bottlenecks for the field by making important reagents, services, or resource pipelines more available, more efficient, and easier for new communities of users to adopt.

Projects supported under this FOA are expected to do one or more of the following: (1) facilitate access to cutting edge reagents or techniques, (2) disseminate existing resources to new groups of users who do not currently have access, and/or (3) develop innovative strategies that increase the scale and efficiency of producing and delivering resources to the neuroscience community. In practical terms, an application might propose establishing or expanding a resource center, production pipeline, distribution network, training-and-access model, or other infrastructure that directly results in more researchers being able to obtain and use a resource. The program is aimed at meeting compelling needs across broad segments of neuroscience researchers or providing specialized services that would otherwise be unavailable.

A key boundary in this announcement is that proposals focused primarily on technology development or software development are considered non-responsive. In other words, the program is not intended to function as a general tool-building mechanism. The priority is not creating new platforms for their own sake, but making resources available and usable at scale. That said, using existing technologies to generate new reagents or genetic lines that are clearly valuable to the wider neuroscience research community may fit the intent, as long as the central purpose remains provision and dissemination rather than technology invention.

All proposed projects must align with the mission of the National Institute of Neurological Disorders and Stroke (NINDS), meaning the resource should clearly support research relevant to neurological function, neurological disorders, stroke, or related neuroscience areas under NINDS priorities. The intended impact is field-wide: applicants should make a strong case that the resource will have broad uptake, address a real access gap, and materially improve the capacity of neuroscience researchers to carry out high-quality work.

This is a discretionary grant program under the health activity category (CFDA 93.853). Eligible applicants are broad and include various levels of government (state, county, city/township, special districts), public and independent school districts, public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (including small businesses), and other entities as allowed by NIH eligibility rules and the FOA’s additional eligibility clarifications. The award ceiling listed for this opportunity is $350,000, with an expected number of awards of 5. The FOA was created on September 21, 2016, with an original closing date of February 14, 2017.

Overall, the R24 High Impact Neuroscience Research Resource Grants opportunity is best understood as support for resource dissemination and service capacity building in neuroscience: creating or expanding mechanisms that reliably deliver high-value reagents, genetic lines, or other shared resources to many researchers, increasing adoption by new user communities, and improving efficiency and scale of resource production and distribution, all in direct support of the NINDS mission.

FAQs: High Impact Neuroscience Research Resource Grants (R24) - RFA-NS-17-002

What is the High Impact Neuroscience Research Resource Grants (R24) opportunity?

This is an NIH funding opportunity run through the Department of Health and Human Services that supports neuroscience research by expanding access to valuable shared research resources. It is designed to build, scale, distribute, and broadly disseminate resources that many neuroscience investigators can use.

What is the main purpose of this program?

The core goal is to remove bottlenecks in neuroscience by making important reagents, services, or resource pipelines more available, more efficient, and easier for new communities of users to adopt. The program prioritizes resource provision and dissemination at scale rather than hypothesis-driven research projects.

What types of projects does the FOA expect to support?

Supported projects are expected to do one or more of the following:

  • Facilitate access to cutting edge reagents or techniques
  • Disseminate existing resources to new groups of users who do not currently have access
  • Develop innovative strategies to increase the scale and efficiency of producing and delivering resources to the neuroscience community

What are examples of activities that might fit this program?

An application might propose establishing or expanding a resource center, a production pipeline, a distribution network, a training-and-access model, or other infrastructure that directly results in more researchers being able to obtain and use a shared resource.

Is this funding meant for typical hypothesis-driven research projects?

No. The opportunity is positioned as support for resource dissemination and service capacity building rather than for standard hypothesis-driven research projects.

Who is the intended user community for the resources created or expanded under this grant?

The intended impact is field-wide. Applicants are expected to show that the resource will have broad uptake across broad segments of neuroscience researchers, address a real access gap, and improve the capacity of the community to do high-quality work.

What does "high-impact" mean in the context of this FOA?

"High-impact" refers to efforts that remove bottlenecks for the neuroscience field by improving availability, efficiency, scalability, and adoption of valuable shared resources. The resource should be compelling enough to support broad use or provide specialized services that would otherwise be unavailable.

Can a project focus on technology development or software development?

Proposals focused primarily on technology development or software development are considered non-responsive. The program is not intended to function as a general tool-building mechanism.

Can existing technologies be used as part of a responsive application?

Yes, using existing technologies to generate new reagents or genetic lines may fit the intent, as long as the central purpose remains provision and dissemination of resources rather than technology invention.

What kinds of resources does this program aim to expand access to?

The FOA emphasizes shared resources such as reagents, services, or resource pipelines, including resources that can be produced and delivered more efficiently or made available to new communities of users.

Does the proposed project need to align with a specific NIH institute mission?

Yes. All proposed projects must align with the mission of the National Institute of Neurological Disorders and Stroke (NINDS). The resource should clearly support research relevant to neurological function, neurological disorders, stroke, or related neuroscience areas under NINDS priorities.

What is the CFDA number and activity category for this opportunity?

This is a discretionary grant program under the health activity category with CFDA number 93.853.

Who is eligible to apply?

Eligibility is broad and includes, among others:

  • State, county, and city or township governments
  • Special district governments
  • Public and independent school districts
  • Public and private institutions of higher education
  • Federally recognized tribal governments and other tribal organizations
  • Public housing and Indian housing authorities
  • Nonprofit organizations with or without 501(c)(3) status
  • For-profit organizations, including small businesses
  • Other entities as allowed by NIH eligibility rules and the FOA's additional eligibility clarifications

What is the maximum award amount (award ceiling) listed for this opportunity?

The award ceiling listed is $350,000.

How many awards were expected under this FOA?

The expected number of awards was 5.

When was the FOA created and what was the original closing date?

The FOA was created on September 21, 2016, and the original closing date was February 14, 2017.

What is the main boundary that applicants should pay attention to?

The key boundary is responsiveness: applications primarily focused on technology development or software development are non-responsive. The priority is scaling access, distribution, and usability of resources, not building new tools as the primary aim.

What should an applicant emphasize to demonstrate fit with this FOA?

Based on the FOA description, an applicant should emphasize that the project will expand and disseminate a valuable neuroscience resource, remove a major access bottleneck, increase scale and efficiency of delivery, and support broad uptake by the neuroscience community, all in a way that clearly advances the NINDS mission.

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