Opportunity Information: Apply for PA 10 212

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "HIV Incidence Assays with Improved Specificity (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Jun 9, 2010 and posted on Jun 9, 2010.
  • Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public housing authorities/Indian housing authorities County governments City or township governments Special district governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses State governments Public and State controlled institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) released a discretionary grant opportunity titled "HIV Incidence Assays with Improved Specificity (R01)" under funding opportunity number PA 10-212. The central goal of this announcement is to support research that advances laboratory assays used to estimate HIV incidence by making them more specific and dependable at telling the difference between recent (incident) HIV infections and long-standing (chronic) infections. In practical terms, the FOA is looking for projects that can reduce misclassification and improve confidence in incidence measurements, which are crucial for accurately tracking the epidemic, evaluating prevention programs, and guiding public health decisions.

The program uses the NIH R01 mechanism, meaning it is intended for mature, hypothesis-driven or technology-development research projects that can be carried out by a well-defined investigative team with a clear plan and measurable milestones. The announcement does not set a fixed award size or project period. Instead, NIH indicates that both the budget and duration may vary depending on what each proposed project needs and how ambitious or complex the work is. Likewise, NIH does not guarantee a set number of awards; the final number and total dollars awarded depend on the quality of the applications received, the proposed timelines, and the reasonableness of requested costs.

From an eligibility standpoint, the FOA is broadly open to many types of applicants. Eligible organizations include state, county, city or township governments; special district governments; independent school districts; public and private institutions of higher education; and a wide range of nonprofit entities (including both 501(c)(3) and certain non-501(c)(3) nonprofits). For-profit organizations are eligible as well, including small businesses and other for-profit entities. The opportunity also welcomes participation from tribal governments (federally recognized and other than federally recognized) and tribal organizations, as well as tribally controlled colleges and universities. In addition, the eligibility language explicitly includes various mission-focused institutions and community-based entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. Importantly, non-U.S. entities (foreign organizations) and regional organizations are also listed as eligible, along with U.S. territories or possessions and eligible federal agencies, reflecting NIHs intent to encourage wide scientific participation where it strengthens the research.

Administratively, the opportunity is categorized as a health-related grant activity and is associated with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research). There is no cost sharing or matching requirement, which means applicants are not required to provide non-federal funds as a condition of receiving an award. The announcement was posted and created on June 9, 2010, with an original and current closing date of May 7, 2011, and an archive date of June 7, 2011, indicating that it was time-limited and is now part of the historical NIH funding archive rather than an active competition.

For applicants or readers needing the full official announcement details, NIH provided an Additional Information link hosted on the NIH grants site (grants.nih.gov) under the PA 10-212 page. NIH also included contact support through the NIH Office of Extramural Research (OER) web team for access or linking problems, using the email address FBOWebmaster@OD.NIH.GOV.

FAQs: HIV Incidence Assays with Improved Specificity (R01) - PA 10-212

What is the name of this grant opportunity?

The opportunity is titled "HIV Incidence Assays with Improved Specificity (R01)."

Who is offering this funding opportunity?

The funding opportunity was released by the National Institute of Allergy and Infectious Diseases (NIAID), which is part of the National Institutes of Health (NIH).

What is the funding opportunity number (FOA number)?

The FOA number is PA 10-212.

What is the main purpose or central goal of this FOA?

The central goal is to support research that advances laboratory assays used to estimate HIV incidence by making them more specific and dependable at distinguishing recent (incident) HIV infections from long-standing (chronic) infections.

What does "improved specificity" mean in the context of HIV incidence assays?

In this FOA, improved specificity refers to making incidence assays more reliable at correctly classifying whether an HIV infection is recent versus chronic, with a particular emphasis on reducing misclassification.

Why is reducing misclassification important for HIV incidence measurement?

Reducing misclassification improves confidence in incidence estimates, which are important for accurately tracking the epidemic, evaluating prevention programs, and supporting public health decision-making.

What type of grant mechanism does this FOA use?

This program uses the NIH R01 mechanism.

What kinds of projects are typically expected under an R01 mechanism (as described here)?

As described in the FOA summary, the R01 mechanism is intended for mature, hypothesis-driven or technology-development research projects that can be executed by a well-defined investigative team with a clear plan and measurable milestones.

Is there a fixed award amount or fixed project period?

No. The announcement does not set a fixed award size or project period. NIH indicates that both budget and duration may vary depending on project needs and the ambition or complexity of the work proposed.

Does NIH guarantee a specific number of awards under this FOA?

No. NIH does not guarantee a set number of awards. The number of awards and total funding depend on factors such as application quality, proposed timelines, and whether requested costs are reasonable.

What types of organizations are eligible to apply?

The FOA includes broad eligibility. Eligible applicants include various government entities (state, county, city or township), special district governments, and independent school districts; public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); and for-profit organizations (including small businesses and other for-profit entities).

Are tribal governments and tribal organizations eligible?

Yes. Eligibility explicitly includes tribal governments (federally recognized and other than federally recognized), tribal organizations, and tribally controlled colleges and universities.

Are community-based or faith-based organizations eligible?

Yes. The eligibility language explicitly includes faith-based or community-based organizations among the eligible entity types.

Are Historically Black Colleges and Universities (HBCUs) and Hispanic-serving institutions eligible?

Yes. The eligibility list explicitly includes HBCUs and Hispanic-serving institutions.

Are Alaska Native and Native Hawaiian-serving institutions included in eligibility?

Yes. Alaska Native and Native Hawaiian-serving institutions are explicitly included in the eligibility language.

Can foreign (non-U.S.) organizations apply?

Yes. Non-U.S. entities (foreign organizations) are listed as eligible, and regional organizations are also included.

Are U.S. territories or possessions eligible to apply?

Yes. U.S. territories or possessions are included in the eligibility language.

Are federal agencies eligible to apply?

Yes. The eligibility language includes eligible federal agencies.

Is this opportunity considered health-related?

Yes. The opportunity is categorized as a health-related grant activity.

What CFDA numbers are associated with this FOA?

The FOA is associated with CFDA 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research).

Is there a cost sharing or matching requirement?

No. There is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal funds as a condition of receiving an award.

When was this FOA posted and created?

The announcement was posted and created on June 9, 2010.

What were the closing date and archive date for this FOA?

The original and current closing date listed is May 7, 2011, and the archive date is June 7, 2011.

Is this an active funding opportunity today?

Based on the provided dates (closing date in 2011 and archive date in 2011), this FOA was time-limited and is now part of the historical NIH funding archive rather than an active competition.

Where can someone find the official announcement details?

NIH provided an Additional Information link hosted on the NIH grants site (grants.nih.gov) under the PA 10-212 page.

Who should be contacted for technical problems accessing the FOA web page (such as linking issues)?

For access or linking problems, NIH directed users to contact the NIH Office of Extramural Research (OER) web team at FBOWebmaster@OD.NIH.GOV.

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