Opportunity Information: Apply for RFA HD 16 034
Apply for RFA HD 16 034
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Jul 7, 2015 and posted on Jul 7, 2015.
- Applicants must submit their applications by Jan 14, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Public housing authorities/Indian housing authorities For profit organizations other than small businesses Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Special district governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity "HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R21)" (Funding Opportunity Number RFA-HD-16-034) is a discretionary NIH research grant designed to stimulate targeted, early-stage studies on how adolescents and youth living with HIV move from pediatric or adolescent-focused health services into adult care systems. The central aim is to build a stronger evidence base that can inform practical, real-world transition guidelines that work across a range of settings, including low-, middle-, and high-income countries. In other words, the program is looking for research that can clarify what successful transition looks like, what gets in the way, what helps, and which approaches can be demonstrated to improve continuity of care and health outcomes when young people age out of pediatric care structures and enter adult clinics and services.
This opportunity uses the NIH R21 mechanism, which is commonly intended for exploratory and developmental research. That generally signals an emphasis on innovative ideas, pilot studies, feasibility testing, and early evidence that can later support larger, more definitive projects. The FOA anticipates making a small number of awards, with an expected total of two awards. The estimated total funding amount listed is $500,000, and the award ceiling is $200,000. There is no cost-sharing or matching requirement, which means applicants are not required to provide non-federal matching funds as a condition of receiving an award.
The activity category is listed under Health, Income Security, and Social Services, reflecting the fact that transition from pediatric to adult HIV care is not only a clinical handoff but also a broader service-delivery and systems issue. Transition often involves changes in insurance or coverage, confidentiality expectations, appointment structures, case management intensity, psychosocial supports, and the patient-provider relationship. By focusing on "transition," NIH is pointing to a known risk period where youth can disengage from care, fall out of treatment, or experience declines in adherence to antiretroviral therapy, all of which can worsen individual outcomes and increase transmission risk at the population level. The FOA is therefore oriented toward generating evidence that can be translated into guidance and implementation strategies that clinics and health systems can actually use.
A notable feature of this announcement is the breadth of eligible applicants. Eligibility includes a wide range of U.S.-based entities such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations other than small businesses, school districts, and multiple levels of government (state, county, city/township, special district). It also includes tribal entities and organizations, including federally recognized Native American tribal governments and other tribal organizations, as well as public housing authorities/Indian housing authorities. Beyond these, the FOA explicitly allows additional applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). Faith-based or community-based organizations and eligible federal agencies are also listed. Importantly, the opportunity allows non-U.S. entities (foreign organizations), regional organizations, and U.S. territories or possessions, which aligns with the stated goal of producing guidance relevant across different income settings and health system contexts worldwide.
From an administrative standpoint, the opportunity was posted on July 7, 2015, with an original and current closing date of January 14, 2016, and an archive date of February 14, 2016. The administering agency is the National Institutes of Health, and the CFDA number provided is 93.865 (Child Health and Human Development Extramural Research), indicating the programmatic home aligns with child and adolescent health priorities. For applicants or readers needing the official announcement, the additional information link points to the NIH Grants Guide page for the RFA. The contact listed for access or technical linking issues is the NIH Office of Extramural Research (OER) Webmaster via FBOWebmaster@OD.NIH.GOV.
Overall, this FOA can be understood as a focused research call to improve one of the most vulnerable points in the HIV care continuum for young people: the shift from pediatric models of care, which often provide more intensive wraparound support, into adult systems that may expect greater independence, have different clinic cultures, and may offer less structured social support. NIH is seeking studies that can help define effective transition processes, measure outcomes that matter (such as retention in care, viral suppression, adherence, and psychosocial stability), and produce findings that can be generalized or adapted to diverse resource environments so that transition guidelines are evidence-driven rather than based mainly on expert opinion or isolated local practice.
FAQs: HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R21) (RFA-HD-16-034)
What is the purpose of this funding opportunity?
This NIH discretionary research grant supports targeted, early-stage studies on how adolescents and youth living with HIV transition from pediatric or adolescent-focused health services into adult care systems. The goal is to strengthen the evidence base so that practical, real-world transition guidelines can be developed and used across many settings, including low-, middle-, and high-income countries.
What problem is NIH trying to address with this opportunity?
The transition from pediatric to adult HIV care is widely recognized as a high-risk period when young people may disengage from care, experience declining adherence to antiretroviral therapy, or have worse health outcomes. This program focuses on generating evidence about what makes transitions successful, what barriers cause drop-off, what supports help, and which approaches can improve continuity of care and outcomes.
What types of studies does the R21 mechanism support here?
The opportunity uses the NIH R21 mechanism, which is typically designed for exploratory and developmental research. This generally points to innovative ideas, pilot studies, feasibility testing, and early evidence that can later support larger, more definitive research projects.
What does "transition" mean in the context of this FOA?
In this context, "transition" refers to the shift of adolescents and youth living with HIV from pediatric or adolescent-oriented care models into adult clinic and service settings. It is not only a clinical handoff, but also a change in service delivery expectations and systems that can affect engagement and outcomes.
Why is the transition period considered a systems and service-delivery issue (not just a clinical issue)?
Transition can involve changes in insurance or coverage, confidentiality expectations, appointment structures, case management intensity, psychosocial supports, and the patient-provider relationship. These changes can alter how easy it is for a young person to stay connected to care and treatment.
What outcomes or measures are emphasized in the description?
The description highlights outcomes that matter to the HIV care continuum and young peoples well-being, including retention in care, viral suppression, adherence to antiretroviral therapy, and psychosocial stability.
How many awards are expected?
The FOA anticipates making a small number of awards, with an expected total of two awards.
How much funding is available under this opportunity?
The estimated total funding amount listed is $500,000, and the award ceiling is $200,000.
Is cost sharing or matching required?
No. There is no cost-sharing or matching requirement, meaning applicants are not required to provide non-federal matching funds as a condition of receiving an award.
What is the activity category for this grant?
The activity category is listed under Health, Income Security, and Social Services, reflecting that transitioning to adult HIV care involves clinical care plus broader supports and service systems.
Who is eligible to apply?
Eligibility is broad. It includes many U.S.-based entities such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations other than small businesses, school districts, and multiple levels of government (state, county, city/township, special district). Tribal governments and other tribal organizations are included, as are public housing authorities/Indian housing authorities.
Are minority-serving institutions specifically included?
Yes. The FOA explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI).
Can faith-based or community-based organizations apply?
Yes. Faith-based or community-based organizations are listed among eligible applicants.
Can federal agencies apply?
Yes. Eligible federal agencies are listed among eligible applicants.
Are non-U.S. organizations allowed to apply?
Yes. The opportunity allows non-U.S. entities (foreign organizations), as well as regional organizations and U.S. territories or possessions. This aligns with the stated goal of producing guidance relevant across different income settings and health system contexts worldwide.
Which agency administers this opportunity?
The administering agency is the National Institutes of Health (NIH).
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-HD-16-034.
What is the name of the opportunity?
The opportunity is titled "HIV infected Adolescents Transitioning from Pediatric to the Adult Care Settings (R21)."
What CFDA number is associated with this FOA?
The CFDA number provided is 93.865 (Child Health and Human Development Extramural Research).
When was this opportunity posted and when did it close?
It was posted on July 7, 2015. The original and current closing date is January 14, 2016, and the archive date is February 14, 2016.
Where can applicants find the official announcement?
The information provided indicates that the additional information link points to the NIH Grants Guide page for the RFA.
Who should be contacted for access or technical linking issues?
The contact listed for access or technical linking issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the overall intent of the research supported by this FOA?
The intent is to improve one of the most vulnerable points in the HIV care continuum for young people by defining effective transition processes, clarifying barriers and facilitators, testing approaches that improve continuity of care, and producing findings that can be generalized or adapted across diverse resource environments so guidelines are evidence-driven.
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