Opportunity Information: Apply for PA 12 280
Apply for PA 12 280
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "HIV/AIDS, Drug Use, and Vulnerable Populations in the US (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Sep 10, 2012 and posted on Sep 10, 2012.
- Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Small businesses Public and State controlled institutions of higher education For profit organizations other than small businesses State governments Independent school districts County governments City or township governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
This grant opportunity, titled "HIV/AIDS, Drug Use, and Vulnerable Populations in the US (R21)" (Funding Opportunity Number PA-12-280), is a National Institutes of Health (NIH) discretionary research grant designed to support exploratory and developmental studies that sit at the intersection of HIV/AIDS disparities and drug use in the United States. Even with major advances in HIV prevention and treatment, the announcement highlights that large and persistent disparities remain, especially among groups that experience disproportionate risk and barriers to care. The focus is on understanding how drug abuse, including both injection and non-injection drug use, can drive HIV acquisition, transmission, and poorer health outcomes, and on building practical interventions that reduce new infections and improve the health and quality of life of people living with HIV.
A central theme of the FOA is the emphasis on vulnerable populations, explicitly including racial and ethnic minority communities, men who have sex with men (MSM), and youth. The opportunity encourages research that clarifies the pathways through which drug use increases HIV risk in these groups, whether through direct biological exposure (for example, injection-related transmission) or through indirect mechanisms such as changes in sexual risk behavior, impaired judgment, overlapping social and sexual networks, or reduced engagement in prevention and treatment services. In addition to studying acquisition and transmission, the FOA also supports work that looks at HIV disease progression and outcomes in the context of drug use, recognizing that substance use can complicate adherence, continuity of care, and overall clinical stability for individuals living with HIV.
The announcement lays out several broad research objectives that applicants can address. First, it supports studies aimed at understanding the contribution of drug abuse to HIV acquisition and/or transmission, across different drugs and modes of use. Second, it invites research on disease progression and disease outcomes, which may include clinical endpoints, comorbidities, care engagement, or other health indicators relevant to HIV. Third, it encourages the development or improvement of prevention and treatment interventions, with particular interest in comprehensive, integrated approaches. That emphasis on integration signals interest in interventions that do not treat HIV risk or HIV care in isolation, but instead coordinate substance use prevention or treatment with HIV prevention tools and clinical HIV services in ways that match real-world needs. Fourth, the FOA aims to improve the availability, delivery, and quality of evidence-based prevention and treatment services across a variety of settings, suggesting that implementation-focused studies, service delivery models, and strategies to strengthen uptake and fidelity can be responsive to the announcement. Fifth, it specifically calls for research that addresses organizational, structural, and community-level factors linked to disparities, including the influence of social networks, drug-using networks, and sexual networks, as well as other contextual drivers that shape risk and access to care.
From an administrative and eligibility standpoint, this is an NIH grant mechanism under CFDA 93.279 (Drug Abuse and Addiction Research Programs). It does not require cost sharing or matching. The listed award ceiling is $200,000. The opportunity was posted and created on September 10, 2012, with an original and final closing date of January 7, 2016, and an archive date of February 7, 2016. That means the specific FOA is archived and not currently open, but the summary still reflects NIH priorities that often reappear in updated funding announcements, especially those centered on HIV disparities, substance use, and integrated prevention and care models.
Eligibility is broad across many types of U.S.-based organizations and governments. Eligible applicants include state, county, city or township governments, special district governments, independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as stated), public housing authorities/Indian housing authorities, small businesses, and for-profit organizations other than small businesses. The FOA also explicitly includes a range of mission- and community-focused institutions and entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Foreign institutions are not eligible to apply, and foreign components are not allowed, including non-U.S. components of U.S. organizations, consistent with NIH policy language included in the announcement.
Overall, the opportunity is geared toward generating actionable knowledge and early-stage evidence that can reduce HIV infections and improve outcomes in communities experiencing the greatest burden, by directly confronting how substance use interacts with HIV risk, treatment, and the social and structural conditions that perpetuate disparities. The full archived announcement was linked through NIH at http://grants.nih.gov/grants/guide/pa-files/PA-12-280.html, and NIH provided webmaster contacts for access or technical issues related to the posting.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "HIV/AIDS, Drug Use, and Vulnerable Populations in the US (R21)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-12-280.
What type of grant mechanism is this?
This is an NIH discretionary research grant using the R21 mechanism, intended to support exploratory and developmental research studies.
What is the main purpose of this FOA?
The FOA supports research at the intersection of HIV/AIDS disparities and drug use in the United States, with the goal of generating actionable knowledge and early-stage evidence that can reduce new HIV infections and improve health outcomes and quality of life for people living with HIV.
What is the central theme of the research focus?
A central theme is improving understanding of HIV/AIDS disparities linked to drug use among vulnerable populations in the U.S., including how substance use affects HIV acquisition, transmission, disease progression, and engagement in prevention and treatment services.
Which vulnerable populations are explicitly highlighted?
The FOA explicitly highlights racial and ethnic minority communities, men who have sex with men (MSM), and youth as vulnerable populations of interest.
What kinds of drug use does the FOA consider relevant?
The FOA considers both injection and non-injection drug use and how each may contribute to HIV acquisition, transmission, and poorer health outcomes.
How does the FOA describe the ways drug use can increase HIV risk?
The FOA notes that drug use can increase HIV risk through direct biological exposure (for example, injection-related transmission) and indirect mechanisms such as increased sexual risk behavior, impaired judgment, overlapping social/sexual networks, and reduced engagement in prevention and treatment services.
Does the FOA address HIV disease progression and outcomes, or only prevention?
It addresses both. In addition to acquisition and transmission, the FOA supports research on HIV disease progression and outcomes in the context of drug use, including issues that can affect adherence, continuity of care, and clinical stability for people living with HIV.
What are the major research objectives listed in the FOA?
The FOA describes several broad objectives, including: (1) understanding the contribution of drug abuse to HIV acquisition and/or transmission; (2) studying HIV disease progression and disease outcomes in the context of drug use; (3) developing or improving prevention and treatment interventions, especially comprehensive and integrated approaches; (4) improving the availability, delivery, and quality of evidence-based prevention and treatment services across settings; and (5) addressing organizational, structural, and community-level factors tied to disparities, including social, drug-using, and sexual networks.
What does "integrated approaches" mean in the context of this FOA?
Based on the FOA description, integrated approaches refer to interventions and service strategies that coordinate substance use prevention or treatment with HIV prevention tools and clinical HIV services, rather than treating HIV risk or HIV care in isolation.
Are implementation and service-delivery studies relevant to this opportunity?
Yes. The FOA indicates interest in improving the availability, delivery, and quality of evidence-based services across settings, which can include implementation-focused studies, service delivery models, and strategies to strengthen uptake and fidelity.
Does the FOA encourage research on structural and community drivers of disparities?
Yes. It specifically calls for research addressing organizational, structural, and community-level factors linked to disparities, including the influence of social networks, drug-using networks, and sexual networks, as well as other contextual drivers shaping risk and access to care.
What is the CFDA number associated with this FOA?
The CFDA listing provided is 93.279 (Drug Abuse and Addiction Research Programs).
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
What is the listed award ceiling?
The listed award ceiling is $200,000.
When was this opportunity posted and created?
The FOA was posted and created on September 10, 2012.
What were the closing dates for this FOA?
The original and final closing date listed is January 7, 2016.
Is this FOA currently open for applications?
No. The FOA is archived. It has an archive date of February 7, 2016, indicating the specific announcement is no longer open.
Does the archived FOA still have relevance for current funding priorities?
The provided summary notes that, while the specific FOA is archived, it reflects NIH priorities that often reappear in updated announcements, particularly those focused on HIV disparities, substance use, and integrated prevention and care models.
Who is eligible to apply?
Eligibility is broad across many U.S.-based organizations and governments, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as stated); public housing authorities/Indian housing authorities; small businesses; and for-profit organizations other than small businesses.
Are community-focused and minority-serving institutions included as eligible applicants?
Yes. The FOA explicitly includes institutions and entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations.
Are U.S. territories or possessions eligible?
Yes. The FOA includes U.S. territories or possessions among eligible applicants.
Are eligible federal agencies allowed to apply?
Yes. The FOA text indicates eligible federal agencies are included among eligible applicants.
Can foreign institutions apply?
No. Foreign institutions are not eligible to apply.
Are foreign components allowed as part of an application?
No. Foreign components are not allowed, including non-U.S. components of U.S. organizations, consistent with the NIH policy language referenced in the FOA.
Where can the archived NIH announcement be found?
The archived announcement was linked at: http://grants.nih.gov/grants/guide/pa-files/PA-12-280.html
What should someone do if they have technical issues accessing the posting?
The summary notes that NIH provided webmaster contacts for access or technical issues related to the posting.
Browse more opportunities from the same agency: National Institutes of Health
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Previous opportunity: FY 2013 CVISN Notice of Funding Availability
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| Funding Opportunity |
|---|
| HIV/AIDS, Drug Use, and Vulnerable Populations in the US (R01) Apply for PA 12 281 Funding Number: PA 12 281 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| AIDS Science Track Award for Research Transition (R03) Apply for PA 12 282 Funding Number: PA 12 282 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Revisions for Early Stage Development of Informatics Technology (R01) Apply for PAR 12 286 Funding Number: PAR 12 286 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Advanced Development of Informatics Technology (U24) Apply for PAR 12 287 Funding Number: PAR 12 287 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Early Stage Development of Informatics Technology (U01) Apply for PAR 12 288 Funding Number: PAR 12 288 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Revisions for Early Stage Development of Informatics Technology (U01) Apply for PAR 12 289 Funding Number: PAR 12 289 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Revisions for Early Stage Development of Informatics Technology (P01) Apply for PAR 12 290 Funding Number: PAR 12 290 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Research Answers to NCIs Provocative Questions Group A (R01) Apply for RFA CA 12 015 Funding Number: RFA CA 12 015 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group A (R21) Apply for RFA CA 12 016 Funding Number: RFA CA 12 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research Answers to NCIs Provocative Questions Group B (R01) Apply for RFA CA 12 017 Funding Number: RFA CA 12 017 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group B (R21) Apply for RFA CA 12 018 Funding Number: RFA CA 12 018 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research Answers to NCIs Provocative Questions Group C (R01) Apply for RFA CA 12 019 Funding Number: RFA CA 12 019 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group C (R21) Apply for RFA CA 12 020 Funding Number: RFA CA 12 020 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research Answers to NCIs Provocative Questions Group D (R01) Apply for RFA CA 12 021 Funding Number: RFA CA 12 021 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research Answers to NCIs Provocative Questions Group D (R21) Apply for RFA CA 12 022 Funding Number: RFA CA 12 022 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Specialized Programs of Research Excellence (SPOREs) in Human Cancer for Years 2013 and 2014 (P50) Apply for PAR 12 296 Funding Number: PAR 12 296 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R01) Apply for PA 12 293 Funding Number: PA 12 293 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R03) Apply for PA 12 294 Funding Number: PA 12 294 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Drug Abuse Aspects of HIV/AIDS (R21) Apply for PA 12 295 Funding Number: PA 12 295 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Mechanism for Time Sensitive Drug Abuse Research (R21) Apply for PAR 12 297 Funding Number: PAR 12 297 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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