Opportunity Information: Apply for PA 13 153
Apply for PA 13 153
- The National Institutes of Health in the food and nutrition health income security and social services sector is offering a public funding opportunity titled "Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Mar 22, 2013 and posted on Mar 22, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education County governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public housing authorities/Indian housing authorities Small businesses Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity PA 13-153, titled "Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)," supports research projects that run randomized clinical trials of new interventions aimed at preventing or managing overweight and obesity during infancy and early childhood. The central idea is to test strategies that work where young children spend most of their time and where key habits form: the home and family setting. The interventions NIH is looking for can be behavioral, such as changes to diet, feeding practices, or physical activity routines, but they can also be environmental or otherwise relevant approaches that influence daily life in the household. In practice, this points to research that does more than observe risk factors; it actively evaluates whether a structured, home- or family-delivered program can change outcomes related to early weight gain.
This announcement uses the R01 Research Project Grant mechanism, meaning it is intended for well-developed, investigator-driven studies with clear hypotheses, strong design, and rigorous evaluation plans. A key expectation embedded in the description is that proposed studies should be randomized clinical trials, which implies attention to trial fundamentals like random assignment, appropriate comparison conditions, meaningful outcome measures, adequate sample sizes, and analytic methods that can credibly attribute any observed effects to the intervention rather than to chance or confounding factors. Because the focus is on infancy and early childhood, successful applications would typically need to show strong plans for recruiting and retaining families, measuring child growth and related behaviors accurately over time, and delivering interventions in ways that fit real-world family life.
The scientific scope is broad within the specific theme of home and family based prevention or management. NIH explicitly notes that interventions may involve behavioral components, including dietary and physical activity approaches, which could cover issues like feeding routines, responsive parenting around hunger and satiety cues, food and beverage choices, family meals, sleep-related behaviors that influence weight risk, and age-appropriate movement or active play. Environmental approaches are also encouraged, which could include modifications to the home food environment (availability, portioning, routines), household norms around screen time and sedentary behavior, or other home-based factors that shape daily energy balance. The emphasis on "novel" interventions suggests NIH was looking for programs that go beyond standard advice and are designed to be tested as replicable, potentially scalable models for families with young children.
Administratively, the opportunity is categorized as discretionary funding and uses a grant instrument. It is associated with multiple CFDA numbers, reflecting the cross-cutting nature of childhood obesity research and the multiple NIH institutes involved in related science: 93.837 (Cardiovascular Diseases Research), 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), and 93.865 (Child Health and Human Development Extramural Research). This signals that applications could be relevant to cardiometabolic risk trajectories, diabetes-related risk, nutrition and digestion-related mechanisms, and broader child development and health outcomes, as long as the core focus remains on early childhood overweight/obesity prevention or management through home or family based intervention trials.
Eligibility is intentionally wide. Domestic applicants may include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and a range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. Tribal entities are included, both federally recognized tribal governments and other tribal organizations, along with tribally controlled colleges and universities. The announcement also extends eligibility to specific institution types and community-rooted organizations, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, AANAPISI institutions, and faith-based or community-based organizations. Importantly, the FOA allows non-U.S. entities and foreign institutions to apply, allows non-U.S. components of U.S. organizations to participate, and allows foreign components as defined by NIH policy. That combination indicates NIH was open to international perspectives and multi-site or cross-national research, provided the trial and the intervention fit the FOA goals.
The FOA does not require cost sharing or matching, which reduces financial barriers for applicants and is typical of many NIH research grants. The opportunity was posted and created on March 22, 2013, with an original and current closing date listed as May 7, 2016, and it was archived on June 7, 2016, meaning it is no longer active for new submissions under that specific announcement record. For applicants at the time, full details and official requirements were provided through the NIH grants guide page linked in the announcement, and support for access or technical linking issues was routed through the NIH Office of Extramural Research (OER) webmaster contact.
In plain terms, this grant opportunity was designed to move the field toward evidence-backed, family-centered solutions that can be tested with the rigor of randomized trials during the earliest, most formative window of child development. It targeted interventions that families can realistically implement in everyday life, while still meeting the scientific bar needed to establish whether those interventions truly prevent excessive weight gain or help manage early overweight in young children.
FAQs: NIH PA 13-153 - Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)
What is PA 13-153?
PA 13-153 is an NIH funding opportunity announcement titled "Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)." It supports research projects that run randomized clinical trials of new interventions aimed at preventing or managing overweight and obesity during infancy and early childhood, with an emphasis on strategies delivered in the home and family setting.
What is the main purpose of this funding opportunity?
The purpose is to test whether structured, home- or family-delivered intervention programs can prevent excessive early weight gain or help manage early overweight/obesity in infants and young children. The focus is on interventions that can realistically fit into everyday family life and can be evaluated with rigorous trial methods.
What type of studies does NIH expect under this FOA?
The FOA is designed for randomized clinical trials of novel interventions. This implies attention to core trial elements such as random assignment, appropriate comparison conditions, meaningful outcome measures, adequate sample sizes, and analytic methods that support credible attribution of outcomes to the intervention.
What is the funding mechanism used by this opportunity?
This announcement uses the R01 Research Project Grant mechanism. R01s are intended for well-developed, investigator-driven studies with clear hypotheses, strong study design, and rigorous evaluation plans.
Who is the target population for the interventions?
The target population is infants and young children in early childhood, along with their families, since the interventions are expected to be home- and family-based and delivered during the earliest developmental period when habits form.
What settings should the intervention focus on?
The intervention should focus on the home and family environment, reflecting the idea that young children spend most of their time at home and that key routines and habits influencing weight-related outcomes develop in household settings.
What kinds of interventions are eligible or encouraged?
NIH indicates that interventions can be behavioral, environmental, or other relevant approaches that influence daily household life. Examples mentioned within the scope include changes to diet, feeding practices, and physical activity routines, as well as home-based environmental modifications that shape daily energy balance.
What behavioral components are within scope?
Behavioral components described as relevant include dietary and physical activity approaches. Within that, examples include feeding routines, responsive parenting around hunger and satiety cues, food and beverage choices, family meals, sleep-related behaviors that influence weight risk, and age-appropriate movement or active play.
What environmental approaches are within scope?
Environmental approaches encouraged by NIH include modifications to the home food environment (such as availability, portioning, and routines), household norms around screen time and sedentary behavior, and other home-based factors that influence daily energy balance.
Does the FOA require the intervention to be novel?
Yes. The FOA emphasizes "novel" interventions, suggesting programs should go beyond standard advice and be designed to be tested as replicable and potentially scalable models that families with young children can implement.
Is this FOA about observing risk factors or testing interventions?
It is centered on testing interventions. The description points to research that does more than observe risk factors by actively evaluating whether a structured home- or family-delivered program can change outcomes related to early weight gain.
What are the implied design expectations for applicants?
Because the FOA calls for randomized clinical trials in infancy and early childhood, it implies that strong applications would include plans for recruiting and retaining families, accurately measuring child growth and related behaviors over time, and delivering interventions in ways that fit real-world family routines while maintaining trial rigor.
What kind of outcomes are relevant to this FOA?
The FOA focuses on outcomes related to preventing or managing overweight/obesity during infancy and early childhood, including outcomes related to early weight gain and related behaviors measured over time in the context of a trial.
What is the CFDA/assistance listing information associated with this opportunity?
The opportunity is associated with multiple CFDA numbers: 93.837 (Cardiovascular Diseases Research), 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), and 93.865 (Child Health and Human Development Extramural Research). This reflects the cross-cutting nature of early childhood obesity research and the involvement of multiple NIH institutes.
What does it mean that the opportunity is linked to multiple CFDA numbers?
It signals that applications may align with multiple health and development areas (for example, cardiometabolic risk trajectories, diabetes-related risk, nutrition/digestion-related mechanisms, and broader child health and development), as long as the core focus remains on early childhood overweight/obesity prevention or management using home- or family-based intervention trials.
What is the funding category and instrument for this opportunity?
The FOA is categorized as discretionary funding and uses a grant instrument.
Is cost sharing or matching required?
No. The FOA does not require cost sharing or matching.
Who is eligible to apply (in general terms)?
Eligibility is broad and includes many domestic organization types (higher education, nonprofits, for-profits, and multiple forms of government entities), as well as tribal entities and various institution types such as HBCUs and Hispanic-serving institutions. The FOA also allows non-U.S. entities and foreign institutions to apply and allows foreign components under NIH policy.
Which domestic organizations are eligible to apply?
Domestic applicants may include public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities); for-profit organizations (including small businesses and other for-profits); and government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are tribal entities eligible?
Yes. The FOA includes federally recognized tribal governments and other tribal organizations, along with tribally controlled colleges and universities.
Are community-based and faith-based organizations eligible?
Yes. The announcement explicitly includes faith-based and community-based organizations among eligible applicants.
Are minority-serving institutions mentioned as eligible?
Yes. The FOA lists institution types including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, and AANAPISI institutions as eligible.
Are non-U.S. entities or foreign institutions allowed to apply?
Yes. The FOA allows non-U.S. entities and foreign institutions to apply, allows non-U.S. components of U.S. organizations to participate, and allows foreign components as defined by NIH policy.
Is this funding opportunity still open?
No. The opportunity is archived and is no longer active for new submissions under that specific announcement record.
What were the key dates for this FOA?
The opportunity was posted and created on March 22, 2013. The original and current closing date listed is May 7, 2016. It was archived on June 7, 2016.
Where were applicants directed for official requirements and full details?
Applicants were directed to the NIH grants guide page linked in the announcement for full details and official requirements.
Who was listed as a contact for access or technical linking issues?
Support for access or technical linking issues was routed through the NIH Office of Extramural Research (OER) webmaster contact.
What is the overall goal of this FOA in plain terms?
The overall goal is to move the field toward evidence-backed, family-centered solutions that can be tested with the rigor of randomized trials during the earliest and most formative window of child development, focusing on interventions families can realistically implement in daily life.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 13 153) also looked into and applied for these:
| Funding Opportunity |
|---|
| Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R21) Apply for PA 13 154 Funding Number: PA 13 154 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Phenotyping Embryonic Lethal Knockout Mice (R01) Apply for PAR 13 231 Funding Number: PAR 13 231 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $499,999 |
| Rare Diseases Clinical Research Consortia (RDCRC) for Rare Diseases Clinical Research Network (U54) Apply for RFA TR 13 002 Funding Number: RFA TR 13 002 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $1,250,000 |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) Apply for PAR 14 270 Funding Number: PAR 14 270 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development (R01) Apply for PAR 14 323 Funding Number: PAR 14 323 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| New Technologies for Viral Hepatitis STTR (R41/R42) Apply for PA 15 076 Funding Number: PA 15 076 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| New Technologies for Viral Hepatitis SBIR (R43/R44) Apply for PA 15 077 Funding Number: PA 15 077 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Closed Loop Technologies Clinical and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (R01) Apply for RFA DK 08 012 Funding Number: RFA DK 08 012 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $500,000 |
| Closed Loop Technologies Pilot and Exploratory Clinical and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (R21) Apply for RFA DK 08 013 Funding Number: RFA DK 08 013 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Small Business Innovation Research to Develop New Therapeutics and Monitoring Technologies for Type 1 Diabetes (T1D). Towards an Artificial Pancreas (SBIR) R43/R44) Apply for RFA DK 09 001 Funding Number: RFA DK 09 001 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Type 1 Diabetes TrialNet Clinical Centers (U01) Apply for RFA DK 08 011 Funding Number: RFA DK 08 011 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Translational Research for the Prevention and Control of Diabetes and Obesity (R18) Apply for PAR 09 176 Funding Number: PAR 09 176 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $500,000 |
| Planning Grants for Translational Research for the Prevention and Control of Diabetes and Obesity (R34) Apply for PAR 09 177 Funding Number: PAR 09 177 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $300,000 |
| Basic and Clinical Studies of Congenital Urinary Tract Obstruction (R01) Apply for PA 09 226 Funding Number: PA 09 226 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Innovation Research to Develop New Therapeutics and Monitoring Technologies for Type 1 Diabetes (T1D). Towards an Artificial Pancreas (SBIR) (R43/R44) Apply for RFA DK 10 008 Funding Number: RFA DK 10 008 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) Apply for PAR 10 230 Funding Number: PAR 10 230 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R21) Apply for PAR 10 232 Funding Number: PAR 10 232 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| A GenitoUrinary Development Molecular Anatomy Project (GUDMAP) Database and Website (U01) Apply for RFA DK 10 005 Funding Number: RFA DK 10 005 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Lifestyle Interventions in Overweight and Obese Pregnant Women Consortium (U01) Apply for RFA DK 10 014 Funding Number: RFA DK 10 014 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Feasibility Studies for Clinical Trials in Type 1 Diabetes (R03) Apply for RFA DK 11 007 Funding Number: RFA DK 11 007 Agency: National Institutes of Health Category: Food and Nutrition Health Income Security and Social Services Funding Amount: $50,000 |
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