Opportunity Information: Apply for RFA RM 11 010
Apply for RFA RM 11 010
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Human Heredity and Health in Africa (H3Africa) Bioinformatics Network (U41)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.310 Trans NIH Research Support.
- This funding opportunity was created on Aug 23, 2011 and posted on Aug 23, 2011.
- Applicants must submit their applications by Dec 2, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,100,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Organizations) African institutions are eligible for the awards Non domestic (non U.S.) Entities (Foreign Organizations) are eligible to apply. Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Human Heredity and Health in Africa (H3Africa) Bioinformatics Network (U41) opportunity, listed as Funding Opportunity Number RFA-RM-11-010, is a National Institutes of Health (NIH) cooperative agreement designed to build a continent-spanning bioinformatics network that supports the broader H3Africa Consortium. The core idea is to strengthen how African genomics and health research groups connect to each other, share data and resources, and develop the computing and informatics foundations needed to carry out large-scale, modern genomics research focused on human disease and population health in African settings.
This funding call focuses on practical, innovative, and cost-effective approaches to improving connectivity and overall bioinformatics infrastructure across all major H3Africa components, including H3Africa Collaborative Centers, individual research projects, and associated biorepositories. The network is meant to act as an enabling layer across the consortium, making it easier to coordinate work, communicate across sites and countries, and operate shared or interoperable systems for genomic data handling, analysis, and exchange. A major emphasis is on fostering active interaction and coordination among African research groups working in genomics-based research, with the clear intent of strengthening pan-H3Africa communication and collaboration rather than supporting isolated efforts.
A key expected function of the proposed network is training and capacity-building. The announcement explicitly highlights the need to provide multiple types of bioinformatics training, to offer services and support that help institutions build local bioinformatics capacity, and to promote computational skills among African researchers. In practice, this points to activities such as structured training programs, workshops, mentorship models, shared support services, and the development of local expertise to run analyses, manage data, and maintain computational systems. Alongside training, the FOA also encourages the development of new computational tools tailored to genomics research needs in African contexts, which can include software, workflows, data-management approaches, or other methods that make genomic analysis more feasible and sustainable given local constraints and research priorities.
From an administrative standpoint, this is a discretionary NIH funding opportunity using the Cooperative Agreement mechanism (U41), meaning the NIH is expected to have substantial involvement in the project’s direction and coordination compared with a standard grant. The activity category is Health, and the opportunity anticipated a single award (Expected Awards: 1), positioning the recipient as a central hub or backbone for consortium-wide bioinformatics networking and support. The estimated total funding level was $3,100,000. There is no cost-sharing or matching requirement.
Eligibility is broad across higher education institutions, including private and public/state-controlled institutions, with additional eligible applicants described in the full announcement. Importantly, African institutions and other non-U.S. entities are explicitly eligible to apply, and foreign (non-U.S.) components of U.S. organizations are allowed. The opportunity was posted and created on August 23, 2011, with an original and current closing date of December 2, 2011, and an archive date of January 2, 2012. The relevant NIH program associations include CFDA numbers 93.172 (Human Genome Research) and 93.310 (Trans-NIH Research Support). Further details were provided through the NIH Grants Guide posting, and technical access or linking issues were routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the announcement.
Frequently Asked Questions (FAQs)
What is the funding opportunity called?
The opportunity is titled the Human Heredity and Health in Africa (H3Africa) Bioinformatics Network (U41).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-RM-11-010.
Which agency is offering this opportunity?
This is a National Institutes of Health (NIH) funding opportunity.
What type of award mechanism is being used?
The mechanism is a Cooperative Agreement (U41).
What does it mean that this is a Cooperative Agreement (U41)?
It means NIH is expected to have substantial involvement in the project’s direction and coordination compared with a standard grant.
What is the overall purpose of this opportunity?
The purpose is to build a continent-spanning bioinformatics network that supports the broader H3Africa Consortium by strengthening how African genomics and health research groups connect, share data and resources, and develop the computing and informatics foundations needed for large-scale genomics research focused on human disease and population health in African settings.
What is H3Africa in the context of this announcement?
H3Africa refers to the Human Heredity and Health in Africa Consortium, which this bioinformatics network is intended to support across its major components.
What kinds of activities does the funding call emphasize?
It emphasizes practical, innovative, and cost-effective approaches to improving connectivity and overall bioinformatics infrastructure across major H3Africa components, including Collaborative Centers, individual research projects, and associated biorepositories.
Is the network intended to support isolated, single-site efforts?
No. A central emphasis is on fostering active interaction and coordination among African research groups, strengthening pan-H3Africa communication and collaboration rather than supporting isolated efforts.
Who is the network expected to support within H3Africa?
The network is expected to support all major H3Africa components, including H3Africa Collaborative Centers, individual research projects, and associated biorepositories.
What role is the network expected to play across the consortium?
It is meant to act as an enabling layer across the consortium, making it easier to coordinate work, communicate across sites and countries, and operate shared or interoperable systems for genomic data handling, analysis, and exchange.
Is training and capacity-building part of the expected scope?
Yes. Training and capacity-building are highlighted as key expected functions of the network.
What kinds of training does the announcement indicate are needed?
The announcement highlights the need to provide multiple types of bioinformatics training, offer services and support to help institutions build local bioinformatics capacity, and promote computational skills among African researchers.
What are examples of training or capacity-building activities mentioned or implied?
Examples include structured training programs, workshops, mentorship models, shared support services, and developing local expertise to run analyses, manage data, and maintain computational systems.
Does the opportunity encourage development of new tools?
Yes. It encourages development of new computational tools tailored to genomics research needs in African contexts.
What kinds of tools or methods are contemplated?
They can include software, workflows, data-management approaches, or other methods that make genomic analysis more feasible and sustainable given local constraints and research priorities.
What is the activity category for this opportunity?
The activity category is Health.
How many awards were anticipated?
The opportunity anticipated a single award (Expected Awards: 1).
What does it imply that only one award was expected?
Based on the announcement, it positions the recipient as a central hub or backbone for consortium-wide bioinformatics networking and support.
What was the estimated total funding level?
The estimated total funding level was $3,100,000.
Is cost-sharing or matching required?
No. The announcement states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad across higher education institutions, including private and public/state-controlled institutions, with additional eligible applicants described in the full announcement.
Are African institutions eligible to apply?
Yes. African institutions are explicitly eligible to apply.
Are other non-U.S. entities eligible to apply?
Yes. Other non-U.S. entities are explicitly eligible to apply.
Are foreign (non-U.S.) components of U.S. organizations allowed?
Yes. Foreign components of U.S. organizations are allowed.
When was the opportunity posted and created?
The opportunity was posted and created on August 23, 2011.
What was the application due date?
The original and current closing date listed was December 2, 2011.
When was the opportunity archived?
The archive date was January 2, 2012.
Where were additional details provided?
Additional details were provided through the NIH Grants Guide posting referenced in the announcement.
What CFDA numbers are associated with this opportunity?
The announcement lists CFDA 93.172 (Human Genome Research) and CFDA 93.310 (Trans-NIH Research Support).
Who should be contacted for technical access or linking issues?
Technical access or linking issues were routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the announcement.
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