Human Heredity and Health in Africa (H3Africa) H3Africa Biorepository Grants. (UH2/UH3) | Apply Online

Opportunity Summary:

The Human Heredity and Health in Africa (H3Africa) H3Africa Biorepository Grants (UH2/UH3) funding opportunity, issued by the National Institutes of Health (NIH) under Funding Opportunity Number RFA-RM-11-011, was designed to help build a major shared research resource on the African continent: an H3Africa biorepository. The core purpose of the award was to support an international site in Africa that could reliably receive, process as needed, store, and distribute biological samples generated by H3Africa research projects, while also serving other African genomic research studies. In practical terms, the biorepository envisioned by this FOA would function as a centralized or coordinating hub that strengthens long-term research infrastructure, improves sample stewardship and quality systems, and enables broader scientific use of African biospecimens in a way that supports health research and disease-focused genomics.

This FOA was backed by the NIH Common Fund along with participating NIH Institutes and Centers, and it explicitly aligned with the broader H3Africa initiative, which is a partnership between NIH and the Wellcome Trust. The bigger picture goal of H3Africa is capacity-building: creating sustainable research capability in Africa by using genomics and related approaches to better understand disease and promote health. Within that framework, a well-run biorepository is not just a storage facility; it is an enabling platform for high-quality, ethically grounded, and logistically dependable biomedical research. By supporting the establishment or development of a biorepository, the NIH aimed to make it easier for African-led and Africa-focused genomics projects to manage specimens to international standards and to share them appropriately for future studies.

The funding mechanism was a cooperative agreement, meaning NIH expected substantial programmatic involvement alongside the awardee rather than a hands-off grant structure. The activity category was health, and the relevant CFDA listings were 93.172 (Human Genome Research) and 93.310 (Trans-NIH Research Support). There was no cost sharing or matching requirement stated for applicants, which lowers a common barrier for institutions building infrastructure-heavy resources like biobanks.

Eligibility was centered on non-U.S. entities, with African institutions specifically eligible and explicitly invited. Eligible applicants included foreign organizations located in African countries, non-domestic components of U.S. organizations, and foreign components as defined in the NIH Grants Policy Statement. The opportunity also listed public/state-controlled and private institutions of higher education among eligible applicant types, along with “others” as clarified in the NIH eligibility language. Overall, the eligibility framing reinforced the intention that the biorepository capacity being funded should be based in Africa and benefit African genomics research networks.

Key dates show this was a time-limited solicitation: it was posted September 14, 2011, created October 17, 2011, with an original closing date of December 2, 2011, later extended to December 19, 2011. The archive date was January 19, 2012, indicating the announcement is no longer active but remains part of the historical NIH funding record.

For applicants and institutions wanting to review the full requirements and detailed expectations, the FOA pointed to the NIH grants guide webpage (http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-11-011.html). Administrative help for access or linking issues was directed to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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