Opportunity Information: Apply for RFA RM 16 011
Apply for RFA RM 16 011
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Human Heredity and Health in Africa (H3Africa): Informatics Network (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
- This funding opportunity was created on Aug 08, 2016.
- Applicants must submit their applications by Nov 15, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $2,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Human Heredity and Health in Africa (H3Africa): Informatics Network (U24) funding opportunity (RFA-RM-16-011) is a National Institutes of Health (NIH), Department of Health and Human Services grant solicitation aimed at strengthening genomics research capacity across the African continent through a dedicated informatics network. The central focus is to support and coordinate the data, computing, and bioinformatics infrastructure needed for H3Africa, a major international effort to advance human genetics and health research in African populations. This opportunity is designed not just to maintain what is already in place, but to expand existing capabilities and develop new ones that help researchers generate, manage, analyze, share, and use genomic and related biomedical data at scale.
The award mechanism is a U24 cooperative agreement, which typically means NIH expects to have substantial involvement in the project’s direction and oversight compared with a standard research grant. In practical terms, the informatics network supported under this FOA would be expected to play a hands-on role in implementing consortium-wide solutions and services, supporting capacity building, and enabling effective collaboration among participating sites and investigators. Because H3Africa projects often produce large and complex datasets (for example, sequence data, genotype data, phenotype and clinical information, and other omics datasets), the informatics network is positioned as a backbone resource that helps ensure the consortium can operate efficiently and consistently across multiple institutions and countries.
The opportunity falls under the Health activity category and is associated with CFDA number 93.310. It was posted with a creation date of August 8, 2016, and had an original application closing date of November 15, 2016. The solicitation anticipated a single award (ExpectedAwards: 1), signaling that NIH intended to fund one main coordinating informatics network hub or center rather than multiple separate awards. The maximum budget cap listed is an award ceiling of $2,500,000, indicating the scale of support envisioned for building and sustaining consortium-level informatics services.
Eligibility is listed as “Others (see text field entitled Additional Information on Eligibility for clarification),” which generally signals that the FOA’s full eligibility rules are more specific than the high-level categories shown in the summary and may include particular institution types, geographic considerations, or partnership structures. In the context of H3Africa, eligibility language often emphasizes participation and leadership that supports African-based research capacity, though the exact requirements would be detailed in the full FOA text.
Overall, this grant opportunity is best understood as funding for infrastructure and coordination rather than a single disease-focused research study. The aim is to enable high-quality genomic research on the African continent by investing in the informatics systems, tools, standards, training, and implementation support that make modern genomics possible at consortium scale. By backing an H3Africa Informatics Network, NIH sought to accelerate discovery while also leaving behind durable expertise and technical capacity that strengthens African genomics and health research over the long term.
FAQs: H3Africa Informatics Network (U24) - RFA-RM-16-011
What is the H3Africa: Informatics Network (U24) funding opportunity?
This is a National Institutes of Health (NIH), Department of Health and Human Services funding opportunity titled "The Human Heredity and Health in Africa (H3Africa): Informatics Network (U24)" (RFA-RM-16-011). It is designed to strengthen genomics research capacity across Africa by supporting a dedicated informatics network for the H3Africa consortium.
What is the main purpose of this grant?
The main purpose is to support and coordinate the data, computing, and bioinformatics infrastructure needed for H3Africa. The emphasis is on enabling researchers to generate, manage, analyze, share, and use genomic and related biomedical data at scale, and on expanding and developing new informatics capabilities rather than only maintaining existing systems.
Is this funding for a specific disease research study?
No. Based on the description provided, this opportunity is best understood as funding for infrastructure and coordination. It supports consortium-wide informatics services that make large-scale genomics research possible, rather than a single disease-focused research project.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH), within the Department of Health and Human Services.
What is the funding mechanism, and what does "U24 cooperative agreement" mean?
The award mechanism is a U24 cooperative agreement. This typically means NIH expects substantial involvement in the project’s direction and oversight compared with a standard research grant. The informatics network is expected to play an active, hands-on role in implementing consortium-wide solutions and services and supporting collaboration among sites.
What kinds of activities would the informatics network support?
The informatics network is positioned as a backbone resource for H3Africa and would support consortium-wide data and computing needs, including bioinformatics infrastructure, implementation support, and capacity-building efforts that enable effective collaboration across multiple institutions and countries.
Why is an informatics network needed for H3Africa?
H3Africa projects often generate large and complex datasets such as sequence data, genotype data, phenotype and clinical information, and other omics datasets. The informatics network helps ensure the consortium can handle these data consistently and efficiently across participating sites.
How many awards were expected under this solicitation?
The solicitation anticipated a single award (ExpectedAwards: 1), which suggests NIH intended to fund one primary coordinating informatics network hub or center rather than multiple separate awards.
What is the maximum budget amount mentioned for this opportunity?
The maximum budget cap listed is an award ceiling of $2,500,000, indicating the scale of support envisioned for building and sustaining consortium-level informatics services.
What is the activity category for this opportunity?
The opportunity falls under the Health activity category.
What CFDA number is associated with this funding opportunity?
This opportunity is associated with CFDA number 93.310.
When was the opportunity posted, and what was the application due date?
The posting (creation) date is August 8, 2016, and the original application closing date was November 15, 2016.
Who is eligible to apply?
Eligibility is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)." This indicates the detailed eligibility requirements are more specific than the summary category and would be defined in the full FOA text. In the context described, eligibility often emphasizes participation and leadership that supports African-based research capacity, though the exact requirements would be in the full announcement.
Does this opportunity focus on maintaining current infrastructure or building new capabilities?
It is designed not only to maintain what is already in place, but also to expand existing capabilities and develop new ones that strengthen the consortium’s ability to work with genomic and related biomedical data at scale.
How does this grant support collaboration across Africa?
Because H3Africa spans multiple institutions and countries, the informatics network is intended to provide shared services and consortium-wide solutions that help participating sites and investigators collaborate effectively and operate with consistent approaches to data, computing, and bioinformatics.
What long-term impact is NIH aiming for with this award?
The goal is to accelerate discovery in human genetics and health research in African populations while leaving behind durable expertise and technical capacity that strengthens African genomics and health research over the long term.
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