Opportunity Information: Apply for RFA DK 13 014

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Human Islet Research Network Bioinformatics Center (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Sep 26, 2013 and posted on Sep 26, 2013.
  • Applicants must submit their applications by Feb 27, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $333,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Native American tribal governments (Federally recognized) Small businesses State governments Independent school districts Special district governments Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Human Islet Research Network Bioinformatics Center (U01) opportunity (Funding Opportunity Number RFA-DK-13-014) was a National Institutes of Health (NIH) cooperative agreement intended to stand up a single, network-wide Bioinformatics Center to support the NIDDK-funded Human Islet Research Network. The central purpose of the award was to provide the specialized expertise, data infrastructure, and coordination capacity needed to make the network's scientific data and shared resources easier to store, standardize, integrate, analyze, and, importantly, share across participating projects. In practical terms, the Bioinformatics Center was meant to act as the hub that turns a collection of separately generated datasets into a coherent, usable, and accessible body of information that can be leveraged by the full research community working on human islet biology and diabetes-related questions.

The mechanism for this award was a cooperative agreement (U01), which signals that NIH expected substantial programmatic involvement during the project period rather than a hands-off grant relationship. The activity area is listed under Food and Nutrition/Health, and the CFDA number associated with the program is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting NIDDK's mission space. The announcement was posted on September 26, 2013, and had an application due date of February 27, 2014, with an archive date of March 30, 2014, meaning it is no longer open but remains a useful reference for how NIH structured this type of network support award.

Funding was planned for one expected award, emphasizing the intent to create a single coordinating center rather than multiple competing sites. The estimated total funding level shown is $500,000, and the award ceiling is listed as $333,000, indicating that budgets were capped at that level per award period as specified in the announcement summary. There was no cost sharing or matching requirement, which is typical for many NIH research grants and helps lower barriers for institutions that might not have discretionary funds to contribute.

Eligibility was broad and included a wide range of domestic U.S. organizations and governmental entities, such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, for-profit organizations other than small businesses, and multiple levels of government (state, county, city/township, special district, and independent school districts). It also explicitly included tribal governments (federally recognized and other than federally recognized) and tribal organizations, as well as public housing authorities and Indian housing authorities. The announcement further clarified that a variety of mission-focused and capacity-building institution types could apply, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, and Tribally Controlled Colleges and Universities (TCCUs), along with faith-based or community-based organizations where applicable.

A notable feature of the eligibility language is that non-U.S. entities were also eligible, including foreign organizations and foreign institutions, and that non-U.S. components of U.S. organizations could participate. The FOA also allowed foreign components as defined by the NIH Grants Policy Statement, which is important for bioinformatics and data coordination efforts that may benefit from international expertise, global data standards, or collaborations that extend beyond U.S. borders.

Administrative information in the summary points applicants to the full FOA text via an NIH grants guide link and provides contact routes through the NIH Office of Extramural Research (OER) Webmaster for access or technical problems with the posting. Overall, the opportunity was designed to ensure that the Human Islet Research Network did not just produce valuable datasets, but also had a dedicated, well-supported informatics backbone to maximize their long-term usability, interoperability, and scientific impact through coordinated data sharing and resource management.

Frequently Asked Questions (FAQs)

What is the Human Islet Research Network Bioinformatics Center (U01) opportunity?

It was a National Institutes of Health (NIH) cooperative agreement funding opportunity to establish a single, network-wide Bioinformatics Center to support the NIDDK-funded Human Islet Research Network. The opportunity is identified as Funding Opportunity Number (FON) RFA-DK-13-014.

What was the main purpose of the Bioinformatics Center?

The central purpose was to provide specialized expertise, data infrastructure, and coordination so that the network's scientific data and shared resources could be more easily stored, standardized, integrated, analyzed, and shared across participating projects and the broader research community.

What kinds of problems was this Bioinformatics Center meant to solve for the network?

It was intended to turn separately generated datasets into a coherent, usable, and accessible body of information. In practice, that means improving how data are organized, made interoperable, and made available for reuse in human islet biology and diabetes-related research.

What NIH funding mechanism was used for this opportunity?

The mechanism was a cooperative agreement (U01), which indicates NIH expected substantial programmatic involvement during the project period rather than a fully hands-off grant relationship.

Which NIH Institute/Center is associated with this opportunity?

The opportunity was tied to NIDDK mission space (National Institute of Diabetes and Digestive and Kidney Diseases), as reflected by the associated CFDA listing.

What is the CFDA number associated with this program?

The CFDA number listed is 93.847, titled "Diabetes, Digestive, and Kidney Diseases Extramural Research."

What is the activity area for this funding opportunity?

The activity area is listed under Food and Nutrition/Health.

How many awards were expected to be made?

One award was expected, reflecting the intent to create a single coordinating bioinformatics center rather than multiple competing sites.

What was the estimated total funding level for this opportunity?

The estimated total funding level shown is $500,000.

Was there an award ceiling or budget cap?

Yes. The award ceiling is listed as $333,000, indicating budgets were capped at that level per award period as specified in the announcement summary.

Was cost sharing or matching required?

No. The summary states there was no cost sharing or matching requirement.

When was the announcement posted?

The announcement was posted on September 26, 2013.

What was the application due date?

The application due date was February 27, 2014.

Is this funding opportunity still open?

No. The archive date is March 30, 2014, and the summary indicates it is no longer open, though it can still be used as a reference for how NIH structured this type of network support award.

What types of U.S. organizations were eligible to apply?

Eligibility included a broad set of domestic U.S. organizations and governmental entities, including public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); small businesses; for-profit organizations other than small businesses; and multiple levels of government (state, county, city/township, special district, and independent school districts).

Were tribal governments and tribal organizations eligible?

Yes. The opportunity explicitly included tribal governments (federally recognized and other than federally recognized) and tribal organizations.

Were public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities were included in the eligibility list.

Did the eligibility language include specific institution types like HBCUs or HSIs?

Yes. The announcement highlighted that mission-focused and capacity-building institution types could apply, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, and Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based or community-based organizations where applicable.

Were non-U.S. entities allowed to apply?

Yes. Non-U.S. entities were also eligible, including foreign organizations and foreign institutions.

Could non-U.S. components of U.S. organizations participate?

Yes. The summary states that non-U.S. components of U.S. organizations could participate.

What does it mean that the FOA allowed "foreign components"?

It means the opportunity permitted foreign components as defined by the NIH Grants Policy Statement, which can be relevant for bioinformatics and data coordination work that benefits from international expertise, collaborations, or global data standards.

Where were applicants directed for the full Funding Opportunity Announcement (FOA) text?

The summary indicates applicants were pointed to the full FOA text via an NIH grants guide link.

Who could be contacted for access or technical problems with the posting?

The administrative information referenced contact routes through the NIH Office of Extramural Research (OER) Webmaster for access or technical problems with the posting.

In plain terms, what role was the Bioinformatics Center expected to play within the network?

It was meant to act as the hub that coordinates data management and sharing across the Human Islet Research Network, improving the long-term usability, interoperability, and impact of the network's datasets and shared resources.

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Previous opportunity: Human Islet Research Network Coordinating Center (U01)

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