Opportunity Information: Apply for RFA CK 10 003
Apply for RFA CK 10 003
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Impact of Japanese Encephalitis Vaccination in Cambodia (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
- This funding opportunity was created on Jan 29, 2010 and posted on Jan 29, 2010.
- Applicants must submit their applications by Mar 30, 2010 Note The application is not complete until you have completed the validation process. After you receive the submission receipt email, the next email you will receive will be a message validating or rejecting your submitted application package with errors. Validation may take at least two (2) calendar days however, you may check the status of your application to ensure submission is complete. To guarantee that you comply with the Funding Opportunity Announcement, allocate additional days to file. Non validated applications will not be accepted after the due date. If no validation is received within two (2) calendar days of submission, you may contact Grants.gov. Please refer to the email message generated at the time of application submission for instructions on how to track your application or the Application User Guide, Version 3.0 page 57.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,200,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- The Ministry of Health in Cambodia is the only institution which possesses the scientific and management capability to meet program requirements without jeopardizing or compromising the quality of the research and other activities. The ministry of Health (MoH) in Cambodia includes staff who have been trained in a variety of international settings, including public health scientists, laboratory scientists, clinicians, epidemiologists, information technology professionals, and experts in emerging infectious diseases and vaccine sciences, etc. The MoH collaborates with universities, community groups, private industry, U.S. governmental institutions (e.g., USAID), the World Health Organization (WHO), non governmental organizations, governments of other countries, and others to study and address infectious disease health problems in Cambodia and the surrounding region, leading to public health prevention and control measures that can be applied in developing countries worldwide.
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Opportunity Summary:
The Centers for Disease Control and Prevention (CDC), through its Procurement and Grants Office, released a discretionary funding opportunity called "Impact of Japanese Encephalitis Vaccination in Cambodia (U01)" under Funding Opportunity Number RFA-CK-10-003. It is a cooperative agreement (U01), meaning CDC would be expected to have substantial involvement with the awardee in carrying out the work rather than simply providing funds with minimal federal participation. The program sits in the health activity category and is tied to CFDA 93.283 (CDC Investigations and Technical Assistance). The core goal is practical and evidence-focused: to demonstrate and document the real-world impact of introducing or implementing a Japanese encephalitis (JE) vaccination program in Cambodia using the SA 14-14-2 JE vaccine, while also generating stronger information about JE epidemiology in a setting where disease incidence is relatively higher.
The opportunity is structured around a single award. CDC anticipated funding one project with approximately $300,000 to $500,000 available in fiscal year 2010 for that award, and an estimated total funding amount listed at $1,200,000 (which generally implies support across a multi-year project period, even though the summary does not spell out the exact number of years). Award ceiling and floor are shown as $0 in the listing, which usually indicates that applicants must rely on the narrative announcement for actual budget constraints rather than the database fields. There is no cost sharing or matching requirement, so the selected recipient would not be required to contribute non-federal funds as a condition of the award.
Programmatically, the work is meant to do more than just deliver vaccine doses. It is intended to capture measurable outcomes and credible documentation of impact from the vaccination campaign, which can include tracking changes in disease burden over time, documenting vaccine coverage and implementation quality, and strengthening surveillance and laboratory confirmation to ensure that changes in reported JE cases reflect true epidemiologic trends rather than shifts in reporting alone. Because Cambodia has a higher incidence of JE compared with many other locations, CDC explicitly frames this as an opportunity to learn more about how JE behaves in that context (for example, patterns by geography, season, age group, and clinical presentation) while demonstrating the public health value of SA 14-14-2 vaccination at population level. In practical terms, this type of cooperative agreement typically supports activities like improving or validating case definitions, enhancing sentinel surveillance, supporting specimen transport and diagnostic testing, training clinicians and epidemiologists, analyzing pre- and post-vaccination data, and producing findings that can inform future JE control strategies in Cambodia and potentially other endemic countries.
Eligibility is unusually narrow and is effectively restricted to one entity. The listing states that the Ministry of Health (MoH) in Cambodia is the only institution considered to have the scientific and management capacity to meet the program requirements without compromising the quality of the research and associated activities. The rationale provided is that the MoH has trained staff across relevant disciplines (public health, laboratory sciences, clinical medicine, epidemiology, information technology, emerging infectious diseases, and vaccine sciences) and maintains collaborations with universities, community groups, private industry, other governments, U.S. government partners such as USAID, the World Health Organization, and non-governmental organizations. Those partnerships and in-country authority are positioned as essential for running a national or large-scale vaccination impact evaluation and ensuring results are credible, operationally feasible, and useful for decision-making.
From an administrative standpoint, the opportunity was posted and created on January 29, 2010, with an original and current closing date of March 30, 2010, and an archive date of April 29, 2010. A key procedural detail emphasized in the notice is the Grants.gov validation process: submission is not considered complete until the application package passes validation, and validation can take at least two calendar days. Applicants were warned to build in extra time before the deadline because non-validated applications would not be accepted after the due date. The notice also points applicants to Grants.gov tracking instructions and the Application User Guide (Version 3.0, page 57) for monitoring submission status, and it advises contacting Grants.gov if validation is not received within two days.
For access issues or questions about obtaining the full announcement electronically, the contact listed is PGO TIMS at 770-488-2700, with a general email referenced but not fully displayed in the provided text. Overall, the grant is best understood as a targeted, single-recipient CDC-supported evaluation effort designed to generate strong evidence on the public health impact of SA 14-14-2 Japanese encephalitis vaccination in Cambodia, while simultaneously strengthening understanding of JE epidemiology in a high-incidence setting.
Frequently Asked Questions (FAQs)
What is the name of this CDC funding opportunity?
The funding opportunity is titled "Impact of Japanese Encephalitis Vaccination in Cambodia (U01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-CK-10-003.
Which federal agency is offering this opportunity?
The opportunity is offered by the Centers for Disease Control and Prevention (CDC), through its Procurement and Grants Office.
What type of award is this?
This is a cooperative agreement (U01). In a cooperative agreement, CDC is expected to have substantial involvement with the recipient in carrying out the work, rather than simply providing funds with minimal federal participation.
What health topic or activity category does this fall under?
The program sits in the health activity category.
What CFDA program is associated with this opportunity?
This opportunity is tied to CFDA 93.283, CDC Investigations and Technical Assistance.
What is the main purpose of the project?
The core goal is to demonstrate and document the real-world impact of introducing or implementing a Japanese encephalitis (JE) vaccination program in Cambodia using the SA 14-14-2 JE vaccine, while also generating stronger information about JE epidemiology in a setting where disease incidence is relatively higher.
Is this opportunity focused only on delivering vaccine doses?
No. The work is intended to do more than deliver vaccine doses. It is meant to capture measurable outcomes and credible documentation of impact from the vaccination campaign and strengthen surveillance and laboratory confirmation so changes in reported JE cases reflect true epidemiologic trends rather than changes in reporting.
What kinds of outcomes or evidence is CDC looking for?
Based on the description, the project is expected to document impact and implementation in practical, evidence-focused ways. Examples mentioned include tracking changes in disease burden over time, documenting vaccine coverage and implementation quality, and improving the ability to confirm JE through surveillance and laboratory work.
Why is Cambodia an important setting for this work?
CDC describes Cambodia as a setting where JE incidence is relatively higher, making it a valuable context to learn more about JE epidemiology while evaluating the public health impact of SA 14-14-2 vaccination at the population level.
What epidemiology questions could this project help answer?
The notice highlights strengthening information about JE epidemiology in Cambodia, including potential patterns by geography, season, age group, and clinical presentation.
What specific vaccine is referenced in the opportunity?
The opportunity specifically references the SA 14-14-2 Japanese encephalitis vaccine.
How many awards did CDC expect to make?
The opportunity is structured around a single award. CDC anticipated funding one project.
How much funding was expected to be available?
CDC anticipated approximately $300,000 to $500,000 available in fiscal year 2010 for the single award. The estimated total funding amount listed is $1,200,000.
Does the listing state an award ceiling or floor?
The award ceiling and floor are shown as $0 in the listing, which typically means applicants should rely on the narrative announcement for actual budget constraints rather than those database fields.
Does this opportunity require cost sharing or matching funds?
No. There is no cost sharing or matching requirement described, so the recipient would not be required to contribute non-federal funds as a condition of the award.
Who is eligible to apply?
Eligibility is effectively restricted to one entity. The listing states that the Ministry of Health (MoH) in Cambodia is the only institution considered to have the scientific and management capacity to meet the program requirements without compromising the quality of the research and associated activities.
Why is eligibility limited to Cambodia's Ministry of Health?
The rationale provided is that the MoH has trained staff across relevant disciplines (including public health, laboratory sciences, clinical medicine, epidemiology, information technology, emerging infectious diseases, and vaccine sciences) and maintains collaborations with partners such as universities, community groups, private industry, other governments, USAID, the World Health Organization, and non-governmental organizations. The notice positions these partnerships and in-country authority as essential for a credible, operationally feasible evaluation of vaccination impact.
What kinds of activities might be supported under this cooperative agreement?
The description notes that a cooperative agreement of this type typically supports activities such as improving or validating case definitions, enhancing sentinel surveillance, supporting specimen transport and diagnostic testing, training clinicians and epidemiologists, analyzing pre- and post-vaccination data, and producing findings to inform JE control strategies in Cambodia and possibly other endemic countries.
What is the application timeline (posting and deadline dates)?
The opportunity was posted and created on January 29, 2010. The original and current closing date was March 30, 2010. The archive date was April 29, 2010.
What is the key submission detail related to Grants.gov validation?
Submission is not considered complete until the application package passes Grants.gov validation. The notice emphasizes that validation can take at least two calendar days and warns that applications that are not validated by the deadline would not be accepted after the due date.
How much time should applicants allow for Grants.gov validation?
The notice advises planning for at least two calendar days for the validation process and building in extra time before the deadline.
How can applicants monitor their Grants.gov submission status?
The notice points applicants to Grants.gov tracking instructions and the Application User Guide (Version 3.0, page 57) for monitoring submission status.
What should applicants do if validation is not received within two days?
The notice advises contacting Grants.gov if validation is not received within two days.
Who can be contacted for access issues or help obtaining the full announcement electronically?
The contact listed for access issues or questions about obtaining the full announcement electronically is PGO TIMS at 770-488-2700. A general email is referenced in the notice, but it is not fully displayed in the provided information.
What is the overall intent of the award in plain terms?
Overall, the grant is described as a targeted, single-recipient CDC-supported evaluation effort designed to generate strong evidence on the public health impact of SA 14-14-2 Japanese encephalitis vaccination in Cambodia, while also strengthening understanding of JE epidemiology in a high-incidence setting.
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