Opportunity Information: Apply for CDC RFA PS12 1206

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Implementing a National Framework to Eliminate Mother to Child HIV Transmission in the United States" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.118 Acquired Immunodeficiency Syndrome (AIDS) Activity.
  • This funding opportunity was created on Mar 30, 2012 and posted on Mar 30, 2012.
  • Applicants must submit their applications by May 30, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,122,500.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $424,500.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible applicants that can apply for this funding opportunity are listed below Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) For profit organizations (other than small business) Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) Non domestic (non U.S.) entity A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov.
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Opportunity Summary:

Implementing a National Framework to Eliminate Mother to Child HIV Transmission in the United States (CDC RFA PS12-1206) was a Centers for Disease Control and Prevention cooperative agreement focused on strengthening and coordinating national efforts to eliminate perinatal (mother-to-child) HIV transmission in the United States. The opportunity centered on supporting an established national stakeholder structure and scaling up a proven quality improvement approach, the FIMR HIV Prevention Methodology (FHPM), to help communities identify system gaps and improve perinatal prevention outcomes. Rather than funding direct clinical care alone, the program emphasized convening, coordination, technical assistance, and practical tools that improve how local and regional systems prevent HIV transmission during pregnancy, delivery, and postpartum care.

A major part of the work involved convening the existing Eliminating Mother-to-Child Transmission (EMCT) Stakeholders Group and providing the staffing and operational backbone needed to keep it functioning effectively. The awardee was expected to support six working groups, help manage their activities, and carry out the actions those groups prioritized. This implies project management responsibilities such as meeting planning and facilitation, documentation, follow-up on action items, and ensuring that decisions translate into implementable products and guidance. The intent was to maintain momentum across multiple partners and disciplines so national recommendations could be turned into real-world improvements in programs and systems.

Another core component was leadership of the EMCT Stakeholders Group expert panel on preconception and reproductive health. This reflects the reality that preventing perinatal HIV transmission does not start at delivery; it begins well before pregnancy through HIV prevention, HIV testing, linkage to care, viral suppression, reproductive life planning, and access to appropriate contraception and preconception counseling. The funded organization would be responsible for developing, providing, and disseminating technical assistance and a suite of practical resources, including administrative tools, education and training materials, and other guidance products that stakeholders could use. In plain terms, CDC sought a capable national partner to translate expert recommendations into usable materials that clinicians, health departments, and community programs could adopt.

The third major objective was broad dissemination of the FIMR HIV Prevention Methodology and provision of substantial technical assistance to as many as 60 communities through a dedicated FHPM National Resource Center. FIMR (Fetal and Infant Mortality Review) methodologies are typically used to review cases and systems factors related to poor perinatal outcomes, then drive local action based on findings. In the HIV prevention adaptation, FHPM helps communities examine how their perinatal HIV prevention and care systems function, identify where failures occur (for example, missed HIV testing, gaps in prenatal care engagement, challenges in antiretroviral treatment adherence, poor data sharing, or loss to follow-up), and implement system-level fixes. The National Resource Center concept indicates a centralized hub providing hands-on support, training, consultation, and possibly standardized materials, coaching models, and implementation guidance so local sites can adopt FHPM effectively and consistently.

A fourth aim expanded the value of FHPM beyond HIV by optimizing the methodology to strengthen local perinatal systems around other perinatal sentinel events, including congenital syphilis and other perinatal infections. This component recognizes that the same underlying system weaknesses that allow perinatal HIV transmission (late or absent prenatal care, missed screening, inadequate follow-up, fragmented services, inequities in access) can also contribute to other preventable perinatal infections and adverse outcomes. By refining FHPM for broader sentinel-event use, the program sought to improve overall perinatal public health infrastructure, not just HIV-specific outcomes, and to create a more flexible, scalable approach that communities can apply to multiple urgent perinatal prevention priorities.

From an administrative standpoint, the opportunity was issued as a discretionary cooperative agreement, meaning CDC anticipated substantial involvement and partnership during the period of performance rather than a hands-off grant. CDC expected to make up to three awards. Total estimated funding was $2,122,500, with an award ceiling of $424,500 per award (no award floor was specified), and there was no cost-sharing or matching requirement. The announcement was posted March 30, 2012, and closed May 30, 2012, with an archive date of June 29, 2012. The CFDA listing was 93.118 (AIDS Activity).

Eligibility was broad and included many organization types that could operate at national scale and provide technical assistance, training, and coordination. Eligible applicants included nonprofits (with or without 501(c)(3) status), for-profit organizations (excluding small business), small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community- and faith-based organizations, tribal governments and tribal health entities (including tribal epidemiology centers, urban Indian organizations, and Alaska Native health corporations), and state and local governments (including U.S. territories and freely associated states). Non-U.S. entities were also listed as eligible. The notice also allowed applications by bona fide agents of state or local governments, provided the applicant submitted a legal, binding agreement documenting that status.

Overall, the grant opportunity targeted national coordination and on-the-ground systems improvement to prevent perinatal HIV transmission by aligning stakeholders, strengthening preconception and reproductive health strategies, and scaling a structured review-and-action methodology (FHPM) with intensive technical assistance across dozens of communities. It also aimed to modernize and broaden that methodology so communities could use the same systems-improvement approach to reduce other serious, preventable perinatal infections such as congenital syphilis.

Frequently Asked Questions (FAQs)

What is CDC RFA PS12-1206?

CDC RFA PS12-1206, titled "Implementing a National Framework to Eliminate Mother to Child HIV Transmission in the United States," was a Centers for Disease Control and Prevention (CDC) discretionary cooperative agreement focused on strengthening and coordinating national efforts to eliminate perinatal (mother-to-child) HIV transmission in the United States.

What was the main purpose of this cooperative agreement?

The purpose was to support national coordination and systems improvement to prevent perinatal HIV transmission. The program emphasized convening stakeholders, providing technical assistance, and disseminating practical tools and quality improvement methods (especially the FIMR HIV Prevention Methodology, or FHPM) to help communities identify system gaps and improve perinatal prevention outcomes.

Did this opportunity primarily fund direct clinical care?

No. Rather than funding direct clinical care alone, the opportunity emphasized convening, coordination, technical assistance, and practical resources that improve how local and regional systems prevent HIV transmission during pregnancy, delivery, and postpartum care.

What is the EMCT Stakeholders Group in this opportunity?

The Eliminating Mother-to-Child Transmission (EMCT) Stakeholders Group was an established national stakeholder structure that the awardee was expected to convene and support. The cooperative agreement included providing staffing and operational support to keep the group functioning effectively and to carry out stakeholder-prioritized actions.

What operational responsibilities did the awardee have for the EMCT Stakeholders Group?

The awardee was expected to provide the staffing and operational backbone for the EMCT Stakeholders Group, including supporting six working groups. This implies project management work such as meeting planning and facilitation, documentation, follow-up on action items, and helping ensure that group decisions lead to implementable products and guidance.

How many working groups were to be supported?

The awardee was expected to support six working groups under the EMCT Stakeholders Group and help manage their activities and prioritized actions.

What was the role related to preconception and reproductive health?

A core component was leadership of the EMCT Stakeholders Group expert panel on preconception and reproductive health. This reflects the emphasis that prevention of perinatal HIV transmission begins before pregnancy through prevention, testing, linkage to care, viral suppression, reproductive life planning, contraception access, and preconception counseling.

What types of resources and technical assistance were expected to be developed and shared?

The funded organization was responsible for developing, providing, and disseminating technical assistance and practical resources such as administrative tools, education and training materials, and other guidance products that stakeholders could use.

What is FHPM (FIMR HIV Prevention Methodology)?

FHPM is a quality improvement approach that adapts Fetal and Infant Mortality Review (FIMR) methods for HIV prevention. It helps communities examine how their perinatal HIV prevention and care systems function, identify where failures occur, and implement system-level fixes to improve outcomes.

How does FHPM help communities prevent perinatal HIV transmission?

FHPM supports communities in identifying gaps and failures in perinatal HIV prevention systems (for example, missed HIV testing, gaps in prenatal care engagement, challenges with antiretroviral treatment adherence, poor data sharing, or loss to follow-up) and then implementing local system improvements based on findings.

What was the FHPM National Resource Center?

The opportunity included providing substantial technical assistance to communities through a dedicated FHPM National Resource Center. This was intended to function as a centralized hub offering hands-on support, training, consultation, and standardized materials and implementation guidance so communities could adopt FHPM effectively and consistently.

How many communities could receive FHPM technical assistance?

The cooperative agreement anticipated providing substantial technical assistance to as many as 60 communities.

Was FHPM intended to be used only for HIV?

No. A specific aim was to optimize and expand FHPM beyond HIV by refining the methodology for other perinatal sentinel events, including congenital syphilis and other perinatal infections.

Why did the opportunity include congenital syphilis and other perinatal infections?

The opportunity recognized that system weaknesses contributing to perinatal HIV transmission (such as late or absent prenatal care, missed screening, inadequate follow-up, fragmented services, and inequities in access) can also drive other preventable perinatal infections. By optimizing FHPM for broader sentinel-event use, the program aimed to strengthen overall perinatal public health infrastructure.

What type of funding mechanism was used?

This was a discretionary cooperative agreement. That means CDC anticipated substantial involvement and partnership during the period of performance, rather than a hands-off grant relationship.

How many awards did CDC expect to make?

CDC expected to make up to three awards under this opportunity.

What was the estimated total funding amount?

The total estimated funding was $2,122,500.

What was the award ceiling per award?

The award ceiling was $424,500 per award.

Was there an award floor?

No award floor was specified in the information provided.

Was cost-sharing or matching required?

No. There was no cost-sharing or matching requirement.

When was the opportunity posted and when did it close?

The announcement was posted on March 30, 2012, and closed on May 30, 2012. The archive date was June 29, 2012.

What was the CFDA number for this opportunity?

The CFDA listing was 93.118 (AIDS Activity).

Who was eligible to apply?

Eligibility was broad and included nonprofits (with or without 501(c)(3) status), for-profit organizations (excluding small business), small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community- and faith-based organizations, tribal governments and tribal health entities (including tribal epidemiology centers, urban Indian organizations, and Alaska Native health corporations), and state and local governments (including U.S. territories and freely associated states). Non-U.S. entities were also listed as eligible.

Could for-profit organizations apply?

Yes. For-profit organizations were eligible, excluding small business (as stated in the eligibility description provided).

Could tribal entities apply?

Yes. Eligible applicants included tribal governments and tribal health entities, including tribal epidemiology centers, urban Indian organizations, and Alaska Native health corporations.

Could state, local, territorial, or freely associated state governments apply?

Yes. Eligibility included state and local governments, including U.S. territories and freely associated states.

Were non-U.S. entities eligible?

Yes. Non-U.S. entities were listed as eligible.

Could a bona fide agent of a state or local government apply?

Yes. Applications by bona fide agents of state or local governments were allowed, as long as the applicant submitted a legal, binding agreement documenting that status.

What kinds of capabilities did the opportunity seem to prioritize in an applicant?

Based on the described scope, CDC was seeking a national partner capable of convening and coordinating stakeholders, providing staffing and operational support, developing and disseminating technical assistance and practical tools, and delivering hands-on training and consultation to support FHPM implementation across up to 60 communities.

What is meant by "scaling up a proven quality improvement approach" in this opportunity?

It refers to expanding the adoption and consistent implementation of FHPM across many communities, supported by a national resource center and substantial technical assistance, so local sites can use a structured review-and-action methodology to identify system gaps and improve perinatal prevention outcomes.

What outcomes was this opportunity ultimately trying to improve?

The opportunity aimed to eliminate perinatal HIV transmission by improving perinatal prevention systems before, during, and after pregnancy, and to strengthen local perinatal systems more broadly by optimizing FHPM to address other sentinel events such as congenital syphilis and other perinatal infections.

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