Opportunity Information: Apply for PA 13 051
Apply for PA 13 051
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Improved Biomaterials for Urinary and Dialysis Catheters (STTR) (R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Dec 18, 2012 and posted on Dec 18, 2012.
- Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The grant opportunity "Improved Biomaterials for Urinary and Dialysis Catheters (STTR) (R41/R42)" (Funding Opportunity Number PA-13-051) is a National Institutes of Health (NIH) Small Business Technology Transfer (STTR) solicitation aimed at advancing new catheter biomaterials that perform better in real-world clinical use. The core purpose is to fund early-stage and follow-on research and development that creates or improves materials used in indwelling catheters for urinary drainage and dialysis-related applications, with a strong emphasis on reducing complications that commonly arise from long-term catheter placement. In practical terms, the NIH is looking for technology that can make catheters less likely to attract and hold onto cells and microorganisms, and less likely to trigger harmful inflammatory responses in the body.
A central theme of the announcement is preventing or minimizing biofouling and infection-related problems by addressing adherence at the material surface. Catheters can become a platform where bacteria and other microorganisms attach, multiply, and form biofilms that are difficult to remove and resistant to treatment. In addition, the body can react to catheter materials through local and systemic inflammation, contributing to pain, tissue irritation, blockage, and broader complications that can compromise treatment (for example, disrupting dialysis access or increasing urinary tract infection risk). The FOA encourages innovations in biomaterials and surface technologies that reduce or eliminate cell and microbial attachment while also dampening inflammatory responses to the implanted or indwelling device.
The opportunity is structured as an STTR grant using the R41/R42 mechanism, which typically supports a phased development path: an initial phase focused on feasibility and proof-of-concept work (R41), followed by a second phase supporting more advanced development, optimization, and validation (R42). The eligible applicants are small businesses, consistent with the STTR program design that promotes partnerships between small companies and nonprofit research institutions to translate biomedical research into commercial products and clinically useful technologies.
Administratively, this is a discretionary grant program administered by the NIH, aligned with the NIH mission area reflected in the CFDA listing 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), which fits the dialysis and urinary catheter focus. There is no cost sharing or matching requirement indicated, meaning applicants are not required to provide matching funds as a condition of the award. The announcement was posted and created on December 18, 2012. The original and current closing date listed is January 7, 2016, with an archive date of February 7, 2016, indicating the opportunity is no longer open for new submissions under that specific posting.
The full announcement and official requirements were provided through the NIH grants portal (link included in the source data). For access or technical issues related to the online announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), which serves as the point of contact for difficulties accessing or linking to the funding opportunity materials.
FAQs: Improved Biomaterials for Urinary and Dialysis Catheters (STTR) (R41/R42) - PA-13-051
What is the title of this grant opportunity?
The opportunity is titled "Improved Biomaterials for Urinary and Dialysis Catheters (STTR) (R41/R42)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-13-051.
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity.
What type of program is this?
It is a Small Business Technology Transfer (STTR) solicitation, using the NIH R41/R42 grant mechanism.
What is the main purpose of this STTR opportunity?
The main purpose is to support early-stage and follow-on research and development aimed at creating or improving biomaterials used in indwelling catheters for urinary drainage and dialysis-related applications, with an emphasis on better performance in real-world clinical use.
What kinds of catheters are in scope?
The focus is on indwelling catheters used for urinary drainage and for dialysis-related applications.
What clinical problems is NIH trying to reduce through this program?
The opportunity emphasizes reducing complications associated with long-term catheter placement, especially issues related to infection, biofouling, and inflammatory responses that can lead to pain, tissue irritation, blockage, and broader complications that can compromise treatment.
What does the announcement mean by biofouling?
In this context, biofouling refers to cells and microorganisms attaching to catheter surfaces, multiplying, and forming biofilms that are difficult to remove and can be resistant to treatment.
Why are biofilms on catheters a concern?
Biofilms can make catheters a persistent platform for microbial growth, creating infection-related problems that are hard to eliminate and may contribute to complications during long-term catheter use.
What kinds of technical approaches does the FOA encourage?
The FOA encourages innovations in biomaterials and surface technologies that reduce or eliminate cell and microbial attachment and that also dampen inflammatory responses to the indwelling device.
What does "adherence at the material surface" refer to?
It refers to the tendency of cells and microorganisms to attach to the catheter material surface, which can contribute to biofouling, infection risk, and related complications.
Does the opportunity address inflammation related to catheter placement?
Yes. A key emphasis is reducing harmful local and systemic inflammatory responses triggered by catheter materials, since inflammation can contribute to pain, tissue irritation, blockage, and other complications.
How is the award structured under R41/R42?
The program uses a phased development path: an initial feasibility and proof-of-concept phase (R41), followed by a second phase that supports more advanced development, optimization, and validation (R42).
Who is eligible to apply?
Eligible applicants are small businesses, consistent with the STTR program design.
Does this program involve collaboration with a research institution?
Yes. The STTR program is designed to promote partnerships between small companies and nonprofit research institutions to translate biomedical research into commercial products and clinically useful technologies.
What type of grant is this (financial assistance category)?
It is a discretionary grant program administered by NIH.
Which CFDA listing is associated with this opportunity?
The opportunity is aligned with CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting the dialysis and urinary catheter focus.
Is cost sharing or matching required?
No cost sharing or matching requirement is indicated for this opportunity, meaning applicants are not required to provide matching funds as a condition of the award.
When was this opportunity posted?
The announcement was posted and created on December 18, 2012.
What was the closing date for applications under this posting?
The original and current closing date listed is January 7, 2016.
Is this funding opportunity still open?
No. The listing indicates an archive date of February 7, 2016, and the closing date has passed, so the opportunity is no longer open for new submissions under that specific posting.
Where were the official announcement and requirements provided?
The full announcement and official requirements were provided through the NIH grants portal (via the link included in the source data).
Who should be contacted for technical issues accessing the online announcement?
For access or technical issues related to the online announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Browse more opportunities from the same category: Food and Nutrition Health
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Previous opportunity: Strengthening Disease Prevention Research Capacity for Public Health Action in Guatemala and the Central American Region
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 13 051) also looked into and applied for these:
| Funding Opportunity |
|---|
| Improved Biomaterials for Urinary and Dialysis Catheters (SBIR) (R43/R44) Apply for PA 13 050 Funding Number: PA 13 050 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Technological Improvements to Data Collection in NIDDK Kidney and Urology Clinical Studies (SBIR) (R41/R42) Apply for PA 13 053 Funding Number: PA 13 053 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Technological Improvements to Data Collection in NIDDK Kidney and Urology Clinical Studies (SBIR) (R43/R44) Apply for PA 13 052 Funding Number: PA 13 052 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Research Resource for Human Organs and Tissues (U42) Apply for RFA OD 13 002 Funding Number: RFA OD 13 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Continuation of the Clinical Centers for the Drug Induced Liver Injury Network DILIN (U01) Apply for RFA DK 13 003 Funding Number: RFA DK 13 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| Limited Competition of the MAPP Research Network Data Coordinating Core (U01) Apply for RFA DK 13 501 Funding Number: RFA DK 13 501 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30) Apply for RFA DK 12 023 Funding Number: RFA DK 12 023 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Small Grants for New Investigators to Promote Diversity in Health Related Research (R03) Apply for PAR 13 074 Funding Number: PAR 13 074 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $125,000 |
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| Undergraduate Summer Institutes in Kidney, Urologic and Hematologic Diseases (R25) Apply for RFA DK 13 005 Funding Number: RFA DK 13 005 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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| Addressing Health Disparities in NIDDK Diseases (R01) Apply for PA 13 183 Funding Number: PA 13 183 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Planning Grants for Translating CKD Research into Improved Clinical Outcomes (R34) Apply for RFA DK 13 002 Funding Number: RFA DK 13 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $225,000 |
| Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) Apply for PAR 13 228 Funding Number: PAR 13 228 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| United States Renal Data System (USRDS) Special Study Centers (U01) Apply for RFA DK 13 008 Funding Number: RFA DK 13 008 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Type 1 Diabetes TrialNet Clinical Network Hub (U01) Apply for RFA DK 13 009 Funding Number: RFA DK 13 009 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,000,000 |
| Type 1 Diabetes TrialNet Clinical Centers (U01) Apply for RFA DK 13 010 Funding Number: RFA DK 13 010 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| NIDDK Program Projects (P01) Apply for PAR 13 266 Funding Number: PAR 13 266 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Multi Center Clinical Study Implementation Planning Cooperative Agreements (U34) Apply for PAR 13 268 Funding Number: PAR 13 268 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $225,000 |
| Limited Competition for the Continuation of a National Endoscopic Database (U01) Apply for RFA DK 13 504 Funding Number: RFA DK 13 504 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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