Opportunity Information: Apply for RFA DK 11 029
Apply for RFA DK 11 029
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Improving Adherence in Pre teens, Adolescents and Young Adults with Type 1 Diabetes (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 21, 2011 and posted on Nov 2, 2011.
- Applicants must submit their applications by Mar 2, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $20,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $400,000.00 in funding.
- Eligible applicants include: For profit organizations other than small businesses City or township governments County governments State governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Special district governments Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health announced a discretionary grant opportunity titled "Improving Adherence in Pre-teens, Adolescents and Young Adults with Type 1 Diabetes (DP3)" under Funding Opportunity Number RFA-DK-11-029. The purpose of the program is to support Research Project Grant (DP3) applications that focus on creating new and better ways to improve adherence to medications and prescribed medical regimens for young people living with type 1 diabetes, including day-to-day self-management behaviors. The target population specifically includes pre-teens, adolescents, and young adults, reflecting the well-known challenges with consistent diabetes management during developmental stages marked by changing routines, increasing independence, school or work transitions, and shifting family involvement.
This funding opportunity emphasizes intervention development rather than large-scale definitive testing. Applicants are expected to develop, refine, and pilot test innovative adherence strategies, meaning the work should move beyond a simple concept and produce an intervention that is clearly defined and characterized by the end of the project period. The intended endpoint is practical readiness: the intervention should be shown to be safe, feasible to implement in real-world settings, and acceptable to the young people it is meant to serve (and, where relevant, to families and care teams). If pilot results indicate promise, the intervention should be positioned to advance into a larger efficacy trial after the DP3 project ends. In other words, this FOA is aimed at building strong groundwork, demonstrating early performance and usability, and de-risking the approach before NIH or others invest in more expensive, confirmatory studies.
Administratively, the opportunity uses the grant funding instrument and falls within the Health activity category, with CFDA numbers 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.865 (Child Health and Human Development Extramural Research). The FOA was posted November 2, 2011, created December 21, 2011, and had an application due date of March 2, 2012, with an archive date of April 2, 2012. While this particular announcement is archived and no longer open, the details are still useful as a template for understanding NIH expectations for early-stage behavioral or clinical intervention development projects focused on adherence in youth with type 1 diabetes.
The estimated total program funding listed for the announcement is $20,000,000, and the award ceiling is $400,000. The FOA indicates there is no cost sharing or matching requirement, which is typical for many NIH research grants and reduces barriers for applicants that may not have non-federal funds available to meet a match.
Eligibility is broad across many U.S.-based organization types. Eligible applicants include for-profit organizations (other than small businesses) and small businesses, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), public and private institutions of higher education, and a wide range of government entities such as city or township governments, county governments, state governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly includes several categories of institutions and organizations often referenced in federal funding announcements, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible. In addition, foreign components (as defined by the NIH Grants Policy Statement) are not allowed, reinforcing that the supported work must be conducted entirely within allowable domestic organizational structures.
From a programmatic standpoint, the central theme is improving adherence in a population where adherence difficulties can have immediate and long-term consequences, including increased risk of acute complications and poorer long-term glycemic outcomes. The FOA encourages innovative strategies, which can be interpreted as approaches that go beyond standard education alone and may incorporate novel behavioral supports, technology-enabled tools, family or peer-based supports, clinic workflow innovations, or other systems-level changes, as long as they are directed at improving consistent engagement with medications and medical regimens. A competitive DP3-style application under this type of announcement would be expected to clearly define the adherence problem being addressed, explain why the proposed intervention is likely to work for the targeted age group, and include a strong plan for iterative refinement and pilot testing that produces clear evidence of feasibility and acceptability, along with early signals that the approach could improve adherence enough to justify a later efficacy trial.
The announcement provides an additional information link to the full FOA text hosted by NIH and notes points of contact for technical difficulties accessing the announcement, specifically the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The funding opportunity is titled "Improving Adherence in Pre-teens, Adolescents and Young Adults with Type 1 Diabetes (DP3)."
Which agency and institute announced this opportunity?
This opportunity was announced by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-DK-11-029.
What is the main purpose of the program?
The purpose is to support Research Project Grant (DP3) applications that create new and improved ways to increase adherence to medications and prescribed medical regimens for young people living with type 1 diabetes, including day-to-day self-management behaviors.
Who is the target population for the interventions supported by this FOA?
The target population includes pre-teens, adolescents, and young adults with type 1 diabetes.
Why does this FOA focus on pre-teens, adolescents, and young adults?
The announcement highlights that consistent diabetes management is especially challenging during developmental stages where routines change, independence increases, school or work transitions occur, and family involvement often shifts.
What type of grant mechanism or funding instrument is used?
The opportunity uses the grant funding instrument and is framed as a Research Project Grant (DP3).
What activity category does this opportunity fall under?
The activity category is Health.
What are the CFDA numbers associated with this opportunity?
The CFDA numbers listed are 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.865 (Child Health and Human Development Extramural Research).
Is this FOA currently open for applications?
No. This announcement is archived and is no longer open.
When was the FOA posted and when were applications due?
The FOA was posted on November 2, 2011. The application due date was March 2, 2012.
What is the archive date for this announcement?
The archive date is April 2, 2012.
What is the estimated total program funding?
The estimated total program funding listed for the announcement is $20,000,000.
What is the award ceiling for this FOA?
The award ceiling is $400,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
What is the overall scientific focus of projects under this FOA?
The scientific focus is intervention development to improve adherence to medications and prescribed regimens in youth with type 1 diabetes.
Does this FOA support large, definitive efficacy trials?
No. The announcement emphasizes intervention development rather than large-scale definitive testing.
What stage of work is expected by the end of the project period?
Applicants are expected to develop, refine, and pilot test innovative adherence strategies so that the intervention is clearly defined and characterized by the end of the project period.
What are the expected endpoints for the developed intervention?
The intended endpoint is practical readiness. The intervention should be shown to be safe, feasible to implement in real-world settings, and acceptable to the young people it is meant to serve (and, where relevant, to families and care teams).
What should happen if pilot testing results are promising?
If pilot results indicate promise, the intervention should be positioned to move into a larger efficacy trial after the DP3 project ends.
What kinds of adherence problems is this FOA trying to address?
The FOA is centered on improving consistent engagement with medications and prescribed medical regimens, including day-to-day self-management behaviors, in a population where adherence problems can lead to acute complications and poorer long-term glycemic outcomes.
What types of strategies does the FOA encourage?
The FOA encourages innovative strategies that go beyond standard education alone and may include behavioral supports, technology-enabled tools, family- or peer-based supports, clinic workflow innovations, or other systems-level changes, as long as they are directed at improving adherence.
What is meant by "innovative" in the context of this FOA?
Based on the announcement, innovative approaches are those that move beyond standard education alone and incorporate new behavioral, technological, family/peer, clinical workflow, or systems-level elements aimed at improving adherence.
What would a competitive application be expected to include?
The FOA indicates a strong application would clearly define the adherence problem being addressed, explain why the intervention is likely to work for the targeted age group, and present a plan for iterative refinement and pilot testing that generates clear evidence of feasibility and acceptability, along with early signals of improved adherence to justify a later efficacy trial.
Which organizations are eligible to apply?
Eligibility is broad across many U.S.-based organization types, including for-profit organizations (other than small businesses) and small businesses, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), public and private institutions of higher education, and many types of government entities.
Which types of government entities are included as eligible applicants?
Eligible government entities include city or township governments, county governments, state governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are specific institution categories explicitly included?
Yes. The FOA explicitly includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply.
Are non-U.S. components of U.S. organizations allowed?
No. Non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed under this FOA?
No. The FOA states that foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
Does the FOA provide a link to full announcement details?
Yes. The announcement notes an additional information link to the full FOA text hosted by NIH.
Who is listed as a point of contact for technical difficulties accessing the announcement?
The NIH Office of Extramural Research (OER) webmaster is listed for technical difficulties: FBOWebmaster@OD.NIH.GOV.
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