Opportunity Information: Apply for RFA MH 16 600
Apply for RFA MH 16 600
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Improving Health and Reducing Cardiometabolic Risk in Youth with Serious Emotional Disturbance and Young Adults with Severe Mental Illness (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Aug 12, 2015 and posted on Aug 12, 2015.
- Applicants must submit their applications by Nov 6, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,400,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses Special district governments Public and State controlled institutions of higher education State governments City or township governments For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "Improving Health and Reducing Cardiometabolic Risk in Youth with Serious Emotional Disturbance and Young Adults with Severe Mental Illness (R01)" (Funding Opportunity Number RFA-MH-16-600) is a National Institutes of Health research funding announcement designed to tackle a major and well-documented problem: youth and young adults living with serious mental health conditions often face significantly higher rates of preventable physical health risks that contribute to earlier illness and shortened lifespan. The overall purpose of the announcement is to fund rigorous, real-world effectiveness studies of service interventions that can measurably reduce cardiometabolic and related health risk factors in two specific groups: youth with serious emotional disturbance (SED) and young adults with severe mental illness (SMI). Rather than supporting small, narrowly scoped pilot ideas, the emphasis is on strong research designs that can demonstrate whether innovative service approaches actually work when implemented in typical community or healthcare settings.
A central theme of this FOA is cardiometabolic risk, broadly defined to include common and highly consequential factors such as smoking, obesity, hypertension (high blood pressure), dyslipidemia (unhealthy cholesterol or lipid profiles), low physical activity, substance use, poor physical fitness, and poor diet. The announcement makes clear that these are examples rather than an exhaustive list, and applicants are expected to focus on risk factors that are meaningful drivers of long-term health outcomes in these populations. The point is not simply documenting that risk exists (which is already well established), but testing interventions that can reduce both the prevalence (how many people are affected) and the magnitude (how severe the risk is) of these factors.
Another key goal is improving the "service delivery knowledge" needed to achieve two ambitious system-level outcomes: 100% screening of the target population for common cardiometabolic risks and 100% referral to appropriate care to manage any identified risks. In practical terms, the FOA is pushing applicants to think beyond individual behavior change alone and to address the full pathway from identification (screening) to action (referral and connection to effective care). That includes designing workflows, partnerships, and care coordination models that make screening routine and make follow-up care realistic and reliable, especially for young people whose mental health needs can make routine medical engagement harder.
The FOA strongly encourages population-based approaches, meaning interventions should be designed to reach entire defined populations of youth with SED and/or young adults with SMI within a community, clinic system, school-linked service network, coordinated specialty care program, or another real-world service setting. This population focus is important because cardiometabolic risks do not only affect a small subgroup; they are widespread, often under-detected, and frequently under-treated in these communities. Research projects responsive to this FOA would typically involve system-level strategies such as universal screening protocols, integrated behavioral health and primary care processes, team-based care models, health coaching embedded in mental health programs, coordinated referral networks, measurement-based care for metabolic risk, and approaches that address engagement barriers (transportation, stigma, fragmented care, low follow-through, or competing mental health crises). The announcement is essentially looking for interventions that can be implemented at scale and sustained within service systems, not just interventions that work under ideal conditions.
In terms of award structure and funding context, this is an NIH R01 grant mechanism, which generally supports substantial multi-year research projects. The opportunity is categorized as discretionary, using a grant funding instrument, with a health activity category. At the time of posting (August 12, 2015), the NIH expected to make about 5 awards, with an estimated total funding amount of $2.4 million. There is no cost-sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of the award. The original and current closing date listed is November 6, 2015, and the archive date is December 7, 2015, indicating this specific announcement is historical rather than currently open, though it remains useful as a guide to NIH priorities and the types of projects NIH has sought in this area.
Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include public and state-controlled and private institutions of higher education, nonprofits with or without 501(c)(3) status (including those outside universities), for-profit organizations (other than small businesses are explicitly listed as eligible as well), small businesses, independent school districts, and a wide range of governmental entities such as state, county, city/township, and special district governments. Housing authorities and tribal governments and organizations are also eligible, including federally recognized tribal governments and other tribal organizations. The FOA also explicitly includes many mission-driven institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based and community-based organizations and eligible federal agencies. At the same time, the announcement is clear that non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed, reinforcing that the work must be domestic in scope and implementation.
The administering agency is the National Institutes of Health, and the CFDA number associated with the program is 93.242 (Mental Health Research Grants), indicating the mental health research focus even though the outcomes are cardiometabolic and physical health related. This reflects an important reality behind the FOA: many drivers of early morbidity and mortality in people with serious mental illness are physical health risks that are preventable or treatable, but they often go unaddressed because of fragmented systems and gaps between mental health and general medical care. The FOA is therefore aimed at closing that gap through services research that tests implementable solutions.
For applicants seeking the full original details, the FOA referenced an NIH guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-16-600.html). The contact information provided is primarily technical, directing people who have difficulty accessing the announcement to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV. In short, this funding opportunity was built to accelerate practical, scalable, and evidence-backed service interventions that can systematically find cardiometabolic risk early and ensure that youth with SED and young adults with SMI actually receive the care needed to reduce those risks over time.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "Improving Health and Reducing Cardiometabolic Risk in Youth with Serious Emotional Disturbance and Young Adults with Severe Mental Illness (R01)" and the Funding Opportunity Number is RFA-MH-16-600.
Which agency is administering this funding opportunity?
The administering agency is the National Institutes of Health (NIH).
What is the purpose of this FOA?
The purpose is to fund rigorous, real-world effectiveness studies of service interventions that can measurably reduce cardiometabolic and related health risk factors in (1) youth with serious emotional disturbance (SED) and (2) young adults with severe mental illness (SMI).
Is this focused on research in real-world settings or controlled lab settings?
This FOA emphasizes real-world effectiveness research implemented in typical community or healthcare settings, rather than narrowly scoped pilot projects or studies that only demonstrate impact under ideal conditions.
What populations are the focus of the funded research?
The FOA targets two groups: youth with serious emotional disturbance (SED) and young adults with severe mental illness (SMI).
What kinds of health issues does the FOA consider "cardiometabolic risk"?
The FOA uses a broad view of cardiometabolic risk, including examples such as smoking, obesity, hypertension (high blood pressure), dyslipidemia (unhealthy cholesterol or lipid profiles), low physical activity, substance use, poor physical fitness, and poor diet. These are examples and not an exhaustive list.
Is the goal just to document that cardiometabolic risk exists in these populations?
No. The FOA notes that elevated cardiometabolic risk is already well documented. The priority is testing interventions that reduce both the prevalence (how many people are affected) and the magnitude (how severe the risk is) of meaningful risk factors.
What does the FOA mean by improving "service delivery knowledge"?
It refers to generating practical knowledge about how services should be organized and delivered to achieve system-level outcomes, especially routine screening and reliable follow-up action for identified risks.
What system-level outcomes does the FOA push applicants toward?
The FOA highlights two ambitious outcomes: 100% screening of the target population for common cardiometabolic risks and 100% referral to appropriate care for any identified risks.
Does the FOA emphasize screening and referral, or only behavior change interventions?
The FOA emphasizes the full pathway from identification (screening) to action (referral and connection to effective care). It encourages applicants to address workflows, partnerships, and care coordination that make screening routine and follow-up care realistic and reliable.
What does a "population-based approach" mean in this FOA?
A population-based approach means designing interventions to reach an entire defined population of youth with SED and/or young adults with SMI within a given service system (for example, a community clinic system, school-linked service network, or coordinated specialty care program), rather than focusing only on a small subset.
What are examples of settings where interventions might be implemented?
The FOA references real-world service settings such as community or healthcare systems, clinic systems, school-linked service networks, coordinated specialty care programs, and other typical service environments where youth with SED and young adults with SMI receive care.
What types of intervention strategies does the FOA suggest are responsive?
Examples mentioned include universal screening protocols, integrated behavioral health and primary care processes, team-based care models, health coaching embedded in mental health programs, coordinated referral networks, measurement-based care for metabolic risk, and strategies that address engagement barriers like transportation, stigma, fragmented care, low follow-through, or competing mental health crises.
Is the FOA looking for interventions that can scale and be sustained?
Yes. The FOA is oriented toward interventions that can be implemented at scale and sustained within service systems, not just interventions that succeed only under ideal conditions.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R01 mechanism, which typically supports substantial multi-year research projects.
How many awards did NIH expect to make and what was the estimated total funding?
At the time of posting (August 12, 2015), NIH expected to make about 5 awards, with an estimated total funding amount of $2.4 million.
Is cost sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
When was the closing date for applications?
The listed original and current closing date is November 6, 2015.
Is this FOA currently open?
Based on the dates provided (closing date November 6, 2015 and archive date December 7, 2015), this specific announcement is historical rather than currently open.
What is the archive date for this FOA?
The archive date listed is December 7, 2015.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and governments, including public and state-controlled and private institutions of higher education; nonprofits with or without 501(c)(3) status; for-profit organizations; small businesses; independent school districts; and governmental entities such as state, county, city/township, and special district governments. Housing authorities and tribal governments and organizations are also eligible.
Are mission-driven and minority-serving institutions explicitly included as eligible?
Yes. The FOA explicitly includes HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations and eligible federal agencies.
Are non-U.S. organizations eligible to apply?
No. The FOA states that non-U.S. entities are not eligible to apply.
Are non-U.S. components of U.S. organizations allowed?
No. The FOA states that non-U.S. components of U.S. organizations are not eligible.
Are foreign components permitted under NIH policy for this FOA?
No. The FOA indicates foreign components (as defined by NIH policy) are not allowed.
What is the CFDA number associated with this program?
The CFDA number listed is 93.242 (Mental Health Research Grants).
Why is a mental health CFDA associated with cardiometabolic outcomes?
The FOA frames cardiometabolic and physical health risks as major drivers of early morbidity and mortality among people with serious mental health conditions, and it aims to reduce those preventable risks through services research that closes gaps between mental health and general medical care.
Where can applicants find the full original FOA text?
The FOA references the NIH guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-16-600.html
Who should be contacted for technical trouble accessing the announcement?
The contact provided for difficulty accessing the announcement is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the main problem this FOA is trying to address?
It addresses the well-documented problem that youth and young adults with serious mental health conditions experience significantly higher rates of preventable physical health risks, contributing to earlier illness and shortened lifespan, often compounded by fragmented care systems.
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