Opportunity Information: Apply for RFA MH 14 060
Apply for RFA MH 14 060
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Improving Health and Reducing Premature Mortality in People with Severe Mental Illness (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Mar 12, 2013 and posted on Mar 12, 2013.
- Applicants must submit their applications by Nov 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $499,999.00 in funding.
- Eligible applicants include: State governments Special district governments Native American tribal governments (Federally recognized) City or township governments Public housing authorities/Indian housing authorities Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts For profit organizations other than small businesses County governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The NIH funding opportunity "Improving Health and Reducing Premature Mortality in People with Severe Mental Illness (R01)" (RFA-MH-14-060) focuses on closing a major health gap: people with severe mental illness (SMI) tend to die earlier than the general population, not because of unusual causes, but because common chronic diseases show up more often and earlier. The announcement highlights that heart disease, diabetes, cancer, stroke, and pulmonary disease are the leading drivers of premature mortality in this group. What makes these outcomes especially actionable is that many of the contributors are modifiable risk factors that are already well understood and treatable in the general population, yet they are often not reaching people with SMI in routine, effective ways.
A key emphasis of the FOA is on the elevated and earlier onset of health risks among people with SMI, including smoking, obesity, hypertension, metabolic disorders, substance use, low physical activity, poor physical fitness, and unhealthy diet. The opportunity also calls attention to a practical complication in real-world care: side effects of psychiatric medications can worsen physical health risk, especially through weight gain and metabolic problems. In other words, even when mental health symptoms are being treated appropriately, physical health can deteriorate unless services are designed to prevent or counter these predictable risks. The NIH is essentially signaling that the science of risk reduction exists, but the delivery to this population is inconsistent, under-tested, or not well integrated into the settings where people with SMI actually receive care.
The grant mechanism is an R01, supporting projects for up to five years, with an award ceiling of $499,999. The total estimated funding for the program is $2,000,000. The FOA is oriented toward rigorous effectiveness testing, meaning proposals are expected to move beyond small feasibility pilots and instead evaluate whether innovative service interventions actually work under conditions that resemble real practice. The interventions of interest are those designed to reduce the prevalence and severity of the major modifiable risk factors that shorten lifespan. Importantly, the scope is not limited to adults with SMI; it also includes children and youth with serious emotional disturbances (SED), reflecting an interest in earlier prevention and in addressing risk trajectories before chronic disease becomes established.
Eligibility is broad and includes many types of U.S. organizations and government entities. Eligible applicants include state, county, city/township, and special district governments; federally recognized tribal governments and other tribal organizations; public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); small businesses; and other for-profit organizations (excluding foreign entities). Public housing authorities and independent school districts are also eligible, which fits the service-oriented nature of the topic and the reality that interventions may be delivered in community-based settings. The eligibility language explicitly includes a range of mission-driven institutions such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and Asian American and Pacific Islander-serving institutions, as well as faith-based and community-based organizations and certain eligible federal agencies. Foreign institutions are not eligible, and foreign components are not allowed, reinforcing that the program is intended for domestic implementation and evaluation.
From an applicant standpoint, the core expectation is to propose an innovative services intervention that can realistically be delivered to people with SMI (or youth with SED) and to test it with strong methods appropriate for effectiveness research. While the FOA description does not prescribe a single intervention type, it clearly prioritizes approaches that target the big, preventable drivers of early death in this population, especially those tied to tobacco use, cardiometabolic risk, physical inactivity, diet, and substance use, and it implicitly encourages designing around the realities of psychiatric treatment, including medication-related metabolic effects. The overarching goal is to generate credible evidence on how to bring proven or promising health risk-reduction strategies into the mental health service environments where they are currently "generally unavailable," and to do so in a way that can meaningfully reduce premature mortality over time.
Administrative details included in the source information indicate the opportunity was posted March 12, 2013, with a closing date of November 7, 2013, and an archive date of December 8, 2013. The program is listed under CFDA 93.242 (Mental Health Research Grants). Cost sharing or matching is not required. The sponsoring agency is the National Institutes of Health. The full announcement was available through the NIH grants site at the provided link, and NIH OER webmaster contacts were listed for access or technical issues.
Frequently Asked Questions (FAQs)
What is the purpose of the NIH funding opportunity RFA-MH-14-060?
The opportunity supports research to improve health and reduce premature mortality among people with severe mental illness (SMI). The focus is on closing a major health gap where people with SMI tend to die earlier than the general population, largely due to common chronic diseases that occur more often and earlier in this group.
What health conditions are highlighted as leading drivers of premature mortality for people with SMI?
The announcement highlights heart disease, diabetes, cancer, stroke, and pulmonary disease as leading contributors to premature mortality among people with SMI.
Why does the FOA consider this problem especially actionable?
Many contributors to premature mortality in people with SMI are modifiable risk factors that are well understood and treatable in the general population. The FOA emphasizes that these risk-reduction strategies are often not reaching people with SMI in routine, effective ways.
Which modifiable risk factors does the FOA emphasize?
The FOA emphasizes elevated and earlier-onset health risks in people with SMI, including smoking, obesity, hypertension, metabolic disorders, substance use, low physical activity, poor physical fitness, and unhealthy diet.
How do psychiatric medications factor into the FOA's focus?
The FOA notes that side effects of psychiatric medications can worsen physical health risk, particularly through weight gain and metabolic problems. It underscores that even when mental health symptoms are treated appropriately, physical health can deteriorate unless services are designed to prevent or counter these predictable risks.
What types of interventions is NIH looking to fund under this FOA?
The FOA calls for innovative services interventions that can realistically be delivered to people with SMI (and also children and youth with serious emotional disturbances). The interventions of interest are designed to reduce the prevalence and severity of major modifiable risk factors tied to premature mortality, especially those related to tobacco use, cardiometabolic risk, physical inactivity, diet, and substance use.
Is the FOA limited to adult populations?
No. The scope includes adults with SMI and also includes children and youth with serious emotional disturbances (SED), reflecting interest in earlier prevention and addressing risk trajectories before chronic disease becomes established.
What research approach does the FOA prioritize (feasibility vs. effectiveness)?
The FOA is oriented toward rigorous effectiveness testing. Proposals are expected to go beyond small feasibility pilots and evaluate whether innovative service interventions work under conditions that resemble real-world practice.
What grant mechanism is used for this opportunity?
This funding opportunity uses the NIH R01 research project grant mechanism.
What is the maximum project period for awards under this R01?
Projects may be supported for up to five years.
What is the award ceiling for this opportunity?
The award ceiling listed in the provided information is $499,999.
How much total funding is estimated for the program?
The total estimated funding for the program is $2,000,000.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH).
What CFDA program is this opportunity associated with?
The program is listed under CFDA 93.242 (Mental Health Research Grants).
Which organizations are eligible to apply?
Eligibility is broad and includes many types of U.S. organizations and government entities. Eligible applicants include state, county, city/township, and special district governments; federally recognized tribal governments and other tribal organizations; public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); small businesses; and other for-profit organizations (excluding foreign entities). Public housing authorities and independent school districts are also eligible.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language explicitly includes institutions such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and Asian American and Pacific Islander-serving institutions, as well as faith-based and community-based organizations and certain eligible federal agencies.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible.
Are foreign components allowed under this FOA?
No. Foreign components are not allowed, reinforcing that the program is intended for domestic implementation and evaluation.
What is the overall goal of the FOA in terms of service delivery?
The overarching goal is to produce credible evidence on how to bring proven or promising health risk-reduction strategies into mental health service environments where these services are generally unavailable, and to do so in a way that can meaningfully reduce premature mortality over time.
When was this opportunity posted and when did it close?
Administrative details indicate the opportunity was posted on March 12, 2013, with a closing date of November 7, 2013.
When was the opportunity archived?
The archive date listed is December 8, 2013.
Where was the full announcement available?
The full announcement was available through the NIH grants site (via the provided link in the source information).
Who was listed for access or technical issues related to the announcement?
NIH Office of Extramural Research (OER) webmaster contacts were listed for access or technical issues.
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