Opportunity Information: Apply for RFA OD 16 009

  • The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Research Project Grants (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351,.
  • This funding opportunity was created on Apr 25, 2016 and posted on Apr 25, 2016.
  • Applicants must submit their applications by Aug 01, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA OD 16 009

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Opportunity Summary:

Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Research Project Grants (R24) is an NIH funding opportunity (RFA-OD-16-009) issued by HHS/NIH that supports targeted upgrades to facilities and equipment used for animal model research. Rather than funding entirely new standalone projects, this announcement specifically invites revision applications (sometimes called administrative supplements or grant revisions, depending on the mechanism details) to existing, active NIH research project grant awards. The central idea is to strengthen the physical infrastructure that investigators rely on for animal-based studies, so that ongoing, NIH-funded research programs can be carried out more effectively, safely, and efficiently.

The eligible scope is intentionally flexible because animal model needs vary widely across programs and species. Applicants can request support for specialized equipment that directly enhances animal model research capabilities, and they may also request funds for alteration and renovation (A and R) work. That means the FOA can cover anything from installing or upgrading high-need research equipment tied to animal studies to making physical changes in existing space that improve housing, procedure areas, barrier containment, workflow, environmental control, or other facility characteristics required for the investigator's animal model work. The emphasis is on improvements that clearly connect to the needs of the currently funded research and that materially increase the quality or capacity of animal model research supported under the active award.

A notable expectation in this announcement is an explicit push toward sustainability. NIH indicates that applicants are expected to propose sustainable designs and incorporate green technologies where feasible. In practical terms, this points applicants toward energy- and water-efficient solutions, durable and lower-impact materials, and designs that reduce long-term operating costs while still meeting animal care and research requirements. Proposals are therefore not just judged on whether they solve an immediate research infrastructure problem, but also on whether they represent responsible, forward-looking investments that can be maintained and operated effectively over time.

From an administrative standpoint, the opportunity is categorized as a discretionary grant in the health area, associated with CFDA numbers 93.351. Eligible applicants include a broad range of organizations: public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations both with and without 501(c)(3) status, along with other entities as described in the additional eligibility language in the full announcement. The agency listed is HHS-NIH (NIH11), and the FOA anticipated making a small number of awards (expected awards: 4), indicating a competitive process focused on well-justified, high-impact infrastructure improvements.

Key dates show the FOA was posted on April 25, 2016, with an application closing date of August 1, 2016 (both original and current closing dates are the same). In short, this announcement is designed for currently NIH-funded investigators who can make a strong, concrete case that incremental investments in equipment and/or renovations will directly enhance animal model research outcomes, while also aligning with sustainability and green design expectations.

Frequently Asked Questions (FAQs)

What is the purpose of this NIH funding opportunity?

This funding opportunity supports targeted upgrades to facilities and equipment used for animal model research. The goal is to improve the physical infrastructure that investigators rely on so ongoing NIH-funded animal-based studies can be performed more effectively, safely, and efficiently.

What is the official title and FOA number?

The opportunity is titled "Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Research Project Grants (R24)" and the FOA number is RFA-OD-16-009.

Which agency is offering this grant?

The awarding agency is HHS/NIH. The agency listing included is HHS-NIH (NIH11).

What type of application does this opportunity invite?

This announcement specifically invites revision applications to existing, active NIH research project grant awards. It is not intended to fund entirely new standalone projects.

Is this intended for new projects or existing NIH awards?

It is intended for existing, active NIH research project grant awards. The focus is on improving infrastructure that supports ongoing, NIH-funded research programs.

What kinds of costs or activities can be supported?

The FOA can support specialized equipment that directly enhances animal model research capabilities. It can also support alteration and renovation (A and R) work, meaning physical changes to existing space that improve animal research functionality.

What does "alteration and renovation (A and R)" mean in this context?

A and R refers to making physical changes within existing space to better support animal model research. Examples described in the opportunity include improvements related to housing, procedure areas, barrier containment, workflow, and environmental control.

What facility improvements are considered within scope?

The scope is intentionally flexible and may include improvements to existing space that enhance animal housing and procedure areas, barrier containment, workflow, environmental control, or other facility characteristics required for the investigator's animal model work, as long as the need is clearly tied to the currently funded research.

What equipment purchases are considered within scope?

Applicants may request support for specialized equipment that directly enhances animal model research capabilities. The equipment should be strongly connected to the needs of the currently funded research under the active award.

How flexible is the eligible scope for animal model needs?

The eligible scope is described as intentionally flexible because animal model needs vary widely across programs and species. Proposed upgrades still need to directly support the active, NIH-funded research.

What is the main review emphasis for proposed upgrades?

The emphasis is on improvements that clearly connect to the needs of the currently funded research and that materially increase the quality or capacity of animal model research supported under the active award.

Do proposed improvements need to be tied to a specific active award?

Yes. This opportunity is for revision applications to existing, active NIH research project grant awards, and proposed infrastructure improvements should be justified as directly supporting the research being conducted under that active award.

Does the FOA include sustainability or green design expectations?

Yes. NIH states that applicants are expected to propose sustainable designs and incorporate green technologies where feasible.

What does NIH mean by "sustainable designs" and "green technologies" in this FOA?

The FOA points applicants toward energy- and water-efficient solutions, durable and lower-impact materials, and designs that reduce long-term operating costs while still meeting animal care and research requirements.

Are proposals evaluated only on immediate infrastructure needs?

No. The opportunity indicates proposals are not only judged on whether they solve an immediate research infrastructure problem, but also on whether they represent responsible, forward-looking investments that can be maintained and operated effectively over time.

What is the grant mechanism mentioned in the announcement?

The announcement references "Revisions of Research Project Grants (R24)" and specifies that it invites revision applications to existing, active NIH research project grant awards.

What is the assistance listing (CFDA) number associated with this opportunity?

The opportunity is associated with CFDA number 93.351.

What category of funding is this opportunity listed under?

It is categorized as a discretionary grant in the health area.

Who is eligible to apply?

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations with and without 501(c)(3) status, along with other entities as described in the additional eligibility language in the full announcement.

How many awards does NIH expect to make?

The FOA anticipated making a small number of awards, with expected awards listed as 4.

Does the expected number of awards suggest a competitive process?

Yes. The FOA indicates an expected 4 awards, which implies a competitive process focused on well-justified, high-impact infrastructure improvements.

When was this FOA posted?

The FOA was posted on April 25, 2016.

What is the application due date?

The application closing date is August 1, 2016. The information provided indicates the original and current closing dates are the same.

Is the closing date the same as the original due date?

Yes. The key dates note that both the original and current closing dates are August 1, 2016.

What is the core benefit this opportunity aims to deliver to funded research programs?

The core benefit is improved capacity, quality, safety, and efficiency for animal model research by strengthening the physical infrastructure supporting ongoing, NIH-funded studies.

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