Opportunity Information: Apply for PAR 16 202

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Improving Smoking Cessation in Socioeconomically Disadvantaged Populations via Scalable Interventions (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399,.
  • This funding opportunity was created on Apr 18, 2016 and posted on Apr 18, 2016.
  • Applicants must submit their applications by Jun 13, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PAR 16 202

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Opportunity Summary:

The grant opportunity "Improving Smoking Cessation in Socioeconomically Disadvantaged Populations via Scalable Interventions (R01)" (Funding Opportunity Number PAR 16-202) is a discretionary research grant from the U.S. Department of Health and Human Services, National Institutes of Health (HHS-NIH11). Its core aim is to fund intervention-focused research that can measurably improve smoking cessation outcomes among people who are socioeconomically disadvantaged. The emphasis is not just on creating interventions that work in a small or idealized study setting, but on building or refining approaches that can realistically be expanded and delivered at scale to produce broad population-level impact. This means the program is looking for research that is both innovative and practical, with a clear pathway to wider reach, sustained implementation, and meaningful public health benefit.

At the center of the FOA is the expectation that proposed interventions be intentionally designed for socioeconomically disadvantaged populations rather than simply including such groups as a subset of a broader sample. The announcement is meant to stimulate research that directly addresses the barriers these populations often face when trying to quit smoking, such as limited access to clinical services, reduced availability of cessation medications, high stress burdens, unstable housing or employment, lower health literacy, competing life priorities, and difficulty maintaining follow-up contact. In practice, this could include interventions that are culturally and contextually tailored, reduce friction and cost for participants, and are deliverable through channels that disadvantaged communities already use and trust.

The FOA allows for two broad kinds of projects. First, applicants may propose the development and testing of entirely new smoking cessation interventions that have real potential to be scaled up. These could be novel behavioral, technology-enabled, community-based, health system-based, or hybrid approaches, as long as the work is intervention research aimed at cessation and designed with scalability in mind. Second, applicants may propose studies that improve interventions that are already being delivered at scale (or could be), with the goal of enhancing their effectiveness and real-world performance for socioeconomically disadvantaged smokers. This includes projects that improve the quality of delivery, increase accessibility and utilization, strengthen engagement and retention, and improve cost-effectiveness. In other words, the FOA is open both to creating new solutions and to making existing solutions work better, reach more people, and deliver stronger outcomes in disadvantaged settings.

Scalability is a recurring theme throughout the announcement. Projects are expected to consider how an intervention could be disseminated broadly without requiring unrealistic staffing, specialized resources, or high per-person costs. Applicants are encouraged to think about delivery models that can fit within real-world systems such as community clinics, public health programs, housing authorities, schools or adult education settings, Medicaid-serving health systems, quitlines, mobile health platforms, and other widely accessible channels. Research that explicitly examines issues like adoption, implementation feasibility, maintenance over time, and economic impact aligns well with the FOA's intent, particularly when those factors are tied back to improving cessation outcomes for disadvantaged populations.

The funding mechanism is the NIH R01, which generally supports substantial, hypothesis-driven research projects. This FOA provides support for up to five years, covering the full arc of work needed to plan the research, deliver the intervention, and conduct follow-up assessments. That timeline is meant to allow for careful intervention design, rigorous testing, and adequate outcome measurement, including longer-term cessation endpoints when appropriate. The funding activity categories listed for this opportunity are education and health, and the associated CFDA numbers are 93.399.

Eligibility is broad and includes many types of institutions and organizations that could credibly carry out intervention research and recruit disadvantaged populations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions, which are separately listed); for-profit organizations other than small businesses; and small businesses. The listing also notes "Others" with additional eligibility details referenced in the full announcement, indicating that NIH may allow additional applicant categories depending on circumstances spelled out in the FOA.

Key administrative details include an original and current closing date of June 13, 2019, with the opportunity posted on April 18, 2016, and created the same day. The award ceiling and expected number of awards are not specified in the provided source data, which is common for some NIH announcements where budgets depend on the scope of the proposed research and institute priorities. Overall, the opportunity is designed to push the field toward smoking cessation strategies that are not only effective in controlled trials, but also deliverable, affordable, and impactful at scale for populations that bear a disproportionate burden of tobacco use and its health consequences.

Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "Improving Smoking Cessation in Socioeconomically Disadvantaged Populations via Scalable Interventions (R01)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PAR 16-202.

Which federal agency is offering this funding?

This is a discretionary research grant offered by the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), listed as HHS-NIH11.

What is the main goal of this FOA?

The core goal is to fund intervention-focused research that can measurably improve smoking cessation outcomes among people who are socioeconomically disadvantaged, with a strong emphasis on interventions that can realistically be delivered at scale for broad population-level impact.

Who is the intended population for the proposed interventions?

Interventions are expected to be intentionally designed for socioeconomically disadvantaged populations, rather than simply including these groups as a subset within a broader study sample.

What kinds of barriers should proposed projects address?

The FOA highlights real-world barriers that can interfere with quitting, including limited access to clinical services, reduced availability of cessation medications, high stress burdens, unstable housing or employment, lower health literacy, competing life priorities, and difficulty maintaining follow-up contact.

What types of projects are allowed under this FOA?

The FOA allows two broad categories of projects: (1) development and testing of new smoking cessation interventions with clear potential to be scaled up, and (2) studies that improve interventions that are already being delivered at scale (or could be) to enhance real-world effectiveness for socioeconomically disadvantaged smokers.

Does the FOA support creating brand-new interventions?

Yes. Applicants may propose the development and testing of entirely new smoking cessation interventions, as long as the work is intervention research aimed at cessation and designed with scalability in mind.

Does the FOA support improving existing smoking cessation programs?

Yes. The FOA also supports research that improves interventions that already operate at scale (or could), including efforts to strengthen effectiveness and performance for socioeconomically disadvantaged smokers in real-world settings.

What does the FOA mean by "scalable" interventions?

Scalable interventions are those that can be disseminated broadly without relying on unrealistic staffing levels, highly specialized resources, or high per-person costs, and that have a plausible pathway to wider reach, sustained implementation, and meaningful public health benefit.

What outcomes or improvements are applicants encouraged to target when enhancing existing interventions?

The FOA specifically mentions improving quality of delivery, increasing accessibility and utilization, strengthening engagement and retention, and improving cost-effectiveness, with the overall purpose of improving cessation outcomes in disadvantaged settings.

What kinds of intervention approaches might fit this FOA?

The FOA indicates that novel behavioral, technology-enabled, community-based, health system-based, or hybrid approaches could be responsive, as long as they are smoking cessation intervention research and are designed with scalability and real-world delivery in mind.

Where does the FOA suggest interventions could be delivered to support real-world reach?

Examples of delivery channels and systems mentioned include community clinics, public health programs, housing authorities, schools or adult education settings, Medicaid-serving health systems, quitlines, mobile health platforms, and other widely accessible channels used and trusted by disadvantaged communities.

Is implementation and long-term maintenance part of what the FOA is looking for?

Yes. The FOA emphasizes real-world viability and encourages research that examines adoption, implementation feasibility, maintenance over time, and economic impact, especially when those factors are tied to improving cessation outcomes for disadvantaged populations.

What is the funding mechanism for this opportunity?

The funding mechanism is the NIH R01.

How long can the project period last under this FOA?

The FOA provides support for up to five years.

Why does the FOA allow up to five years of support?

The timeline is described as supporting the full arc of work needed to plan the research, deliver the intervention, and conduct follow-up assessments, including longer-term cessation endpoints when appropriate.

Which activity categories are associated with this funding opportunity?

The listed funding activity categories are education and health.

What CFDA number is associated with this opportunity?

The associated CFDA number listed is 93.399.

Who is eligible to apply?

Eligibility is broad and includes state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions, which are listed separately); for-profit organizations other than small businesses; and small businesses.

Does the FOA mention any additional eligible applicants beyond those listed?

Yes. The listing includes "Others" and notes that additional eligibility details are referenced in the full announcement, implying NIH may allow additional applicant categories depending on conditions described in the FOA.

When was this opportunity posted?

The opportunity was posted on April 18, 2016, and it was also created on April 18, 2016.

What was the closing date for applications?

The original and current closing date provided is June 13, 2019.

Is the award ceiling provided?

No. The award ceiling is not specified in the provided information.

Is the expected number of awards provided?

No. The expected number of awards is not specified in the provided information.

Why might an NIH FOA not list an award ceiling or number of awards?

The provided information notes this can be common for some NIH announcements, where budgets depend on the scope of the proposed research and institute priorities.

What makes an application align well with the intent of this FOA?

Applications align well when they propose intervention research focused on smoking cessation for socioeconomically disadvantaged populations and include a clear, realistic pathway for broad dissemination, feasible implementation in real-world systems, sustained delivery over time, and meaningful public health impact.

Does the FOA prioritize controlled trial efficacy or real-world impact?

The FOA emphasizes that interventions should not only work in controlled or idealized study settings, but should also be deliverable, affordable, and impactful at scale in real-world conditions.

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