Opportunity Information: Apply for RFA NR 09 005
Apply for RFA NR 09 005
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Incorporating Cost Effectiveness Analysis Into Factors Affecting Quality of Life Health Related Research (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research.
- This funding opportunity was created on Mar 17, 2009 and posted on Mar 17, 2009.
- Applicants must submit their applications by May 18, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: State governments City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
This opportunity is an NIH Research Project Grant (R01) focused on bringing cost-effectiveness analysis directly into health-related quality of life research. Sponsored by the National Institute of Nursing Research (NINR) along with the National Cancer Institute (NCI) and the Office of Dietary Supplements (ODS), the grant is aimed at studies that evaluate not only whether an intervention improves outcomes, but also whether the benefits justify the costs. The core idea is that decisions in clinical care, public health, and translational research increasingly depend on understanding value, meaning the relationship between what an intervention costs and what it delivers in real-world health improvement, especially from the patient perspective.
The FOA specifically encourages projects that use cost-effectiveness methods to assess interventions designed to improve health outcomes tied to quality of life. It is interested in both acute and chronic conditions, but it places special emphasis on areas commonly associated with quality of life science, including self-management and symptom management. It also highlights health promotion and disease prevention, suggesting interest in interventions that keep people healthier longer, reduce symptom burden, or prevent escalation of disease and disability. Another priority area is work that involves new technologies and improved research methods, which can include novel measurement approaches, analytic techniques, or technology-enabled interventions where cost and value may differ from traditional models of care.
A major motivation behind the announcement is to expand the knowledge base and normalize the routine use of cost-effectiveness analysis in patient-focused and translational research. In practice, that means applicants are expected to go beyond clinical efficacy alone and incorporate economic evaluation in a way that can guide future implementation, scaling, and policy decisions. The FOA frames cost-effectiveness analysis as a tool to increase awareness of value, identify practical next steps for integrating economics into intervention research, and strengthen the evidence needed to decide which approaches should be adopted in clinical settings, community programs, or broader health systems.
This announcement builds on earlier federal efforts to move the field in this direction, referencing two workshops: one sponsored by NINR and Johns Hopkins University in 2004, and another sponsored by NINR and the Office of Rare Diseases in 2008. By positioning the FOA as a continuation of those workshops, NIH is signaling that the grant is meant to accelerate a maturing research agenda where quality-of-life interventions are evaluated with stronger economic rigor and clearer implementation relevance.
The mechanism of support is the standard NIH R01, meaning it is intended for discrete, well-defined research projects with a strong scientific premise and a clear plan for producing publishable, generalizable results. Funding is limited and competitive: NINR expected to commit up to $2,000,000 total to support about 3 to 4 awards, with final totals depending on project quality, duration, and budget needs. The listing shows an award ceiling of $300,000, and awards are contingent on available funds and the submission of enough high-quality applications.
Eligibility is broad and includes many types of applicants across the public and private sectors. Eligible applicants include state and local governments, tribal governments and tribal organizations, public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), small businesses and other for-profit organizations, independent school districts, special district governments, public housing authorities/Indian housing authorities, and additional categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, U.S. territories or possessions, federal agencies, regional organizations, and even non-U.S. entities (foreign organizations). The opportunity does not require cost sharing or matching.
Key administrative details reflect that this was a time-limited announcement. The funding opportunity number is RFA-NR-09-005, it was posted March 17, 2009, and the original and current closing date was May 18, 2009, with an archive date of June 18, 2009. The CFDA listing is 93.361 (Nursing Research), and the sponsoring agency is the National Institutes of Health. For access or technical problems with the online announcement, NIH provided contact information through the NIH Office of Extramural Research (OER) webmaster.
Frequently Asked Questions (FAQs)
1) What is this funding opportunity?
This is an NIH Research Project Grant (R01) funding opportunity focused on integrating cost-effectiveness analysis directly into health-related quality of life research. It supports studies that evaluate not only whether an intervention works, but whether the benefits justify the costs in ways that can inform real-world decisions.
2) What is the main purpose of the FOA?
The purpose is to expand the evidence base and normalize routine use of cost-effectiveness analysis in patient-focused and translational research tied to quality of life. Applicants are expected to go beyond clinical efficacy alone and include economic evaluation that can guide implementation, scaling, and policy decisions.
3) Which NIH organizations are sponsoring or participating in this opportunity?
The opportunity is sponsored by the National Institute of Nursing Research (NINR) along with the National Cancer Institute (NCI) and the Office of Dietary Supplements (ODS).
4) What kinds of research questions is NIH trying to answer with these projects?
The FOA emphasizes questions about value: the relationship between what an intervention costs and what it delivers in real-world health improvement, especially from the patient perspective. Projects should help decision-makers understand whether a quality-of-life-focused intervention is worth its cost.
5) What types of interventions are of interest?
The FOA encourages projects that use cost-effectiveness methods to assess interventions designed to improve health outcomes tied to quality of life. It highlights areas commonly associated with quality of life science, including self-management and symptom management.
6) Are both acute and chronic conditions eligible topics?
Yes. The FOA indicates interest in both acute and chronic conditions, while placing special emphasis on domains commonly tied to quality of life research.
7) Does the FOA prioritize health promotion and prevention research?
Yes. Health promotion and disease prevention are specifically highlighted, suggesting interest in interventions that keep people healthier longer, reduce symptom burden, or prevent escalation of disease and disability.
8) What does the FOA say about technology or new methods?
A stated priority area is work involving new technologies and improved research methods. Examples described at a high level include novel measurement approaches, analytic techniques, or technology-enabled interventions where cost and value may differ from traditional models of care.
9) What is meant by bringing cost-effectiveness analysis into quality of life research?
In this FOA, cost-effectiveness analysis is framed as a practical tool for determining value, increasing awareness of the cost-benefit tradeoffs of interventions, and strengthening evidence needed to decide which approaches should be adopted in clinical settings, community programs, or broader health systems.
10) Why is NIH emphasizing cost-effectiveness in this area?
The announcement states that decisions in clinical care, public health, and translational research increasingly depend on understanding value. The FOA aims to accelerate a research agenda where quality-of-life interventions are evaluated with stronger economic rigor and clearer implementation relevance.
11) How does this FOA relate to prior federal efforts?
The FOA is positioned as a continuation of earlier efforts, referencing two workshops: one sponsored by NINR and Johns Hopkins University in 2004, and another sponsored by NINR and the Office of Rare Diseases in 2008. NIH signals that this opportunity is meant to accelerate this maturing line of work.
12) What is the funding mechanism?
The mechanism is the standard NIH Research Project Grant (R01), intended for discrete, well-defined research projects with a strong scientific premise and a clear plan for producing publishable, generalizable results.
13) How much funding is expected to be available?
NINR expected to commit up to $2,000,000 total to support about 3 to 4 awards. Final totals depend on project quality, duration, and budget needs, and awards are contingent on available funds and the submission of enough high-quality applications.
14) How many awards did NIH expect to make?
The FOA indicates an expectation of approximately 3 to 4 awards, depending on the factors described (quality, duration, and budget needs).
15) Is there an award ceiling listed?
Yes. The listing shows an award ceiling of $300,000.
16) Is cost sharing or matching required?
No. The opportunity explicitly states that it does not require cost sharing or matching.
17) Who is eligible to apply?
Eligibility is broad and includes applicants across the public and private sectors. Examples listed include state and local governments, tribal governments and tribal organizations, public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), small businesses and other for-profit organizations, independent school districts, special district governments, public housing authorities/Indian housing authorities, and additional categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, U.S. territories or possessions, federal agencies, regional organizations, and non-U.S. entities (foreign organizations).
18) Are foreign organizations eligible?
Yes. The eligibility list includes non-U.S. entities (foreign organizations).
19) What is the funding opportunity number?
The funding opportunity number is RFA-NR-09-005.
20) When was the opportunity posted and when did it close?
It was posted on March 17, 2009. The original and current closing date was May 18, 2009. The archive date was June 18, 2009.
21) Is this a current open opportunity?
Based on the provided dates (closing date May 18, 2009 and archive date June 18, 2009), this was a time-limited announcement and is not open within the timeframe shown.
22) What is the CFDA number associated with this opportunity?
The CFDA listing is 93.361 (Nursing Research).
23) Which federal agency is the sponsor?
The sponsoring agency is the National Institutes of Health (NIH).
24) Where were applicants directed for access or technical problems with the online announcement?
For access or technical problems, NIH provided contact information through the NIH Office of Extramural Research (OER) webmaster.
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| Minority Based Community Clinical Oncology Program (U10) Apply for RFA CA 09 023 Funding Number: RFA CA 09 023 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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