Opportunity Information: Apply for CDC RFA IP14 1407

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Increasing IIS Sentinel Site Capacity for Enhanced Program Support" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.268 Immunization Cooperative Agreements.
  • This funding opportunity was created on Jun 4, 2014 and posted on Jun 4, 2014.
  • Applicants must submit their applications by Jul 21, 2014 1. Letter of Intent (LOI) N/A. 2. Application Deadline July 21, 2014, 1159 p.m. U.S. Eastern Standard Time, on www.grants.gov.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,400,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Government Organizations State or their bona fide agents (includes the District of Columbia) Local governments or their bona fide agents
Apply for CDC RFA IP14 1407

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Opportunity Summary:

The CDC funding opportunity titled "Increasing IIS Sentinel Site Capacity for Enhanced Program Support" (Funding Opportunity Number CDC RFA IP14 1407) is a discretionary cooperative agreement aimed at strengthening Immunization Information Systems (IIS) Sentinel Sites so they can better support modern immunization program demands. The central goal is to help IIS programs keep vaccination coverage high, respond more effectively to outbreaks of vaccine preventable diseases (VPDs), and improve the ability to track and evaluate the impact of VPD prevention efforts. The opportunity reflects the growing expectation that IIS platforms do more than store immunization records; they are increasingly relied on as core public health infrastructure for real-time decision-making, program operations, and emergency response.

A major emphasis of the announcement is on expanding IIS Sentinel Site capacity in two priority areas that were receiving heightened attention at the time: pandemic response readiness and Human Papilloma Virus (HPV) prevention. For pandemic response, the intent is to ensure Sentinel Sites can support rapid, large-scale immunization activities, including the ability to manage surges in vaccination volume, improve situational awareness, and help public health agencies coordinate provider participation and reporting during emergencies. For HPV prevention, the grant highlights the need for IIS enhancements that support initiatives to improve HPV vaccination uptake and to better connect immunization activities with longer-term outcomes relevant to HPV-related cancers.

The funding is specifically restricted to activities that advance this Sentinel Site capacity-building initiative. In other words, award funds must be used to implement enhancements that enable IIS Sentinel Sites to provide stronger program support tied to outbreak response, monitoring of prevention efforts, pandemic-related vaccination needs, and HPV-related initiatives. In addition, for HPV prevention work, the announcement recommends sharing funds with the state Cancer Registry or other databases that track HPV-related outcomes. The purpose of that recommendation is to improve alignment between immunization data and outcome-focused systems so that states can better evaluate HPV prevention efforts and support data-driven cancer prevention strategies.

Administratively, this opportunity was issued by the Centers for Disease Control and Prevention under CFDA 93.268 (Immunization Cooperative Agreements). The CDC anticipated making 6 awards, with an estimated total funding amount of $5.4 million. Individual awards were expected to fall between $200,000 (award floor) and $300,000 (award ceiling), and there was no cost sharing or matching requirement. Eligible applicants were government organizations, specifically states (including the District of Columbia) or their bona fide agents, and local governments or their bona fide agents. The opportunity was posted on June 4, 2014, and applications were due July 21, 2014 by 11:59 p.m. U.S. Eastern time via Grants.gov. No letter of intent was required.

Frequently Asked Questions (FAQ)

What is the name of this CDC funding opportunity?

The funding opportunity is titled "Increasing IIS Sentinel Site Capacity for Enhanced Program Support."

What is the Funding Opportunity Number?

The Funding Opportunity Number is CDC RFA IP14 1407.

What type of funding mechanism is this?

This opportunity is a discretionary cooperative agreement.

What is the main purpose of this cooperative agreement?

The main purpose is to strengthen Immunization Information Systems (IIS) Sentinel Sites so they can better support modern immunization program demands, including maintaining high vaccination coverage, improving outbreak response for vaccine-preventable diseases (VPDs), and strengthening the ability to track and evaluate the impact of VPD prevention efforts.

Why is CDC focusing on IIS Sentinel Site capacity in this opportunity?

The opportunity reflects increasing expectations that IIS platforms serve as core public health infrastructure. In addition to storing immunization records, IIS Sentinel Sites are expected to support real-time decision-making, program operations, and emergency response.

What are the priority focus areas highlighted in the announcement?

The announcement emphasizes expanding IIS Sentinel Site capacity in two priority areas: pandemic response readiness and Human Papilloma Virus (HPV) prevention.

What does the opportunity aim to support for pandemic response readiness?

For pandemic response, the intent is to ensure Sentinel Sites can support rapid, large-scale immunization activities. This includes handling surges in vaccination volume, improving situational awareness, and helping public health agencies coordinate provider participation and reporting during emergencies.

What does the opportunity aim to support for HPV prevention?

For HPV prevention, the grant highlights the need for IIS enhancements that support initiatives to improve HPV vaccination uptake and better connect immunization activities with longer-term outcomes relevant to HPV-related cancers.

Are funds limited to certain activities?

Yes. The funding is specifically restricted to activities that advance the IIS Sentinel Site capacity-building initiative. Award funds must be used to implement enhancements that enable stronger program support tied to outbreak response, monitoring prevention efforts, pandemic-related vaccination needs, and HPV-related initiatives.

Is there any recommendation related to HPV work and other state data systems?

Yes. For HPV prevention work, the announcement recommends sharing funds with the state Cancer Registry or other databases that track HPV-related outcomes, to improve alignment between immunization data and outcome-focused systems and to support evaluation of HPV prevention efforts.

What is the CFDA number associated with this opportunity?

This opportunity was issued under CFDA 93.268 (Immunization Cooperative Agreements).

How many awards did CDC anticipate making?

CDC anticipated making 6 awards.

What was the estimated total funding amount?

The estimated total funding amount was $5.4 million.

What was the expected funding range per award?

Individual awards were expected to range from $200,000 (award floor) to $300,000 (award ceiling).

Is cost sharing or matching required?

No. There was no cost sharing or matching requirement.

Who was eligible to apply?

Eligible applicants were government organizations: states (including the District of Columbia) or their bona fide agents, and local governments or their bona fide agents.

Are non-government organizations eligible to apply?

Only the listed eligible applicants are included in the announcement information provided: states (including DC) or their bona fide agents, and local governments or their bona fide agents.

When was the opportunity posted?

The opportunity was posted on June 4, 2014.

What was the application deadline?

Applications were due July 21, 2014 by 11:59 p.m. U.S. Eastern time.

How were applications submitted?

Applications were submitted via Grants.gov.

Was a letter of intent required?

No. A letter of intent was not required.

What kinds of public health outcomes is the opportunity trying to improve?

The opportunity is intended to help programs keep vaccination coverage high, improve responsiveness to outbreaks of vaccine-preventable diseases, and strengthen tracking and evaluation of prevention efforts. It also emphasizes readiness for pandemic-related vaccination needs and improvements tied to HPV vaccination uptake and HPV-related cancer outcomes.

How does this opportunity describe the evolving role of IIS?

It frames IIS as more than a repository of immunization records. IIS Sentinel Sites are described as increasingly relied on for real-time public health decision-making, program operations, and emergency response.

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