Opportunity Information: Apply for PA 06 527

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Independent Scientist Award (K02)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.173 Research Related to Deafness and Communication Disorders 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research.
  • This funding opportunity was created on Dec 19, 2008 and posted on Aug 16, 2006.
  • Applicants must submit their applications by Jan 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education.
  • Foreign institutions are not eligible to apply. The applicant institution must have a well established record of research career development activities and demonstrate a commitment to research and to the continuing development of the candidate as a productive independent scientist. The institution must provide assurance that the candidate is an integral part of its research and academic program and must certify that the candidate will be released from other duties and be able to devote at least 75 effort to the research program. The institution must also delineate the duties from which the candidate will be released in order to devote this effort.
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Opportunity Summary:

The Independent Scientist Award (K02), Funding Opportunity Number PA 06-527, is a National Institutes of Health (NIH) discretionary grant designed to support newly independent researchers who need a protected, intensive period of research time to strengthen and accelerate their careers. The central idea behind the K02 is to help promising scientists build momentum at a key transition point by providing support that allows them to focus more heavily on research, expand their expertise, and increase their long-term ability to make major contributions in their field. It is a career development-style mechanism that emphasizes sustained research focus rather than short-term project funding alone.

A key feature of this opportunity is that it is not administered as a one-size-fits-all program across NIH. Participating NIH Institutes and Centers (ICs) may apply their own guidelines and expectations, including differences in eligibility nuances, budget structures, salary caps, and the amount of research support provided. Because these IC-specific provisions can materially affect whether an applicant is a good fit and how an application should be framed, prospective candidates are strongly encouraged to contact the relevant IC program staff listed in the announcement’s contacts section before investing significant effort in an application. That early conversation is intended to clarify eligibility, confirm alignment with the Institute’s mission, and prevent applicants from pursuing an approach that conflicts with an IC’s specific K02 requirements.

The applicant organization (the institution that submits the application on behalf of the candidate) must demonstrate a strong environment for research career development and must show a concrete commitment to the candidate’s growth as an independent scientist. In practice, NIH expects the institution to treat the candidate as an integral part of its academic and research program rather than as an isolated hire. A major institutional requirement is protected time: the institution must certify that the candidate will be relieved of other duties sufficiently to devote at least 75 percent effort to the proposed research program. The institution must also explicitly describe which duties will be reduced or removed to make that level of research effort realistic, reinforcing that the award is meant to buy time for deep research concentration rather than adding research on top of a full workload.

Eligibility for applicant organizations is broad within the United States and includes public and state-controlled institutions of higher education, private institutions of higher education, certain nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations other than small businesses, and small businesses, along with other entities as described in the full announcement. However, foreign institutions are not eligible to apply, meaning the applicant institution must be domestic even if collaborations involve international partners. There is no cost sharing or matching requirement indicated for this opportunity.

The scientific areas connected to this announcement span many NIH mission domains, reflected in the range of CFDA program areas associated with it. These include, among others, environmental health; oral diseases and disorders; deafness and communication disorders; sleep disorders; drug abuse and addiction; mental health research career/scientist development; cardiovascular, lung, and blood diseases; arthritis and musculoskeletal and skin diseases; neurosciences and neurological disorders; allergy, immunology, and transplantation; microbiology and infectious diseases; child health and human development; aging; and vision research. This broad scope underscores that the K02 mechanism is a career-stage support tool used across multiple biomedical and behavioral research areas, with the exact fit depending heavily on which NIH Institute or Center is sponsoring the award.

Administratively, the opportunity was posted on August 16, 2006, with multiple application receipt dates listed in the full announcement. The current closing date shown in the provided record is January 7, 2009, with an archive date of January 8, 2009, indicating that the specific announcement version referenced is historical. Applicants looking for a current K02 opportunity would typically need to confirm whether this FOA has been reissued, replaced, or superseded by a newer NIH funding opportunity announcement, and should rely on NIH’s current Guide Notices and active FOAs for up-to-date submission dates and requirements.

For further details, the full announcement is linked at http://grants.nih.gov/grants/guide/pa-files/PA-06-527.html, and NIH’s Office of Extramural Research (OER) provides technical help for accessing the announcement online via the OER webmaster contact listed in the record.

Independent Scientist Award (K02) - PA-06-527: Frequently Asked Questions

1) What is the Independent Scientist Award (K02) under PA-06-527?

The Independent Scientist Award (K02) is an NIH discretionary, career development-style award intended to support newly independent researchers. Its purpose is to provide a protected, intensive period of research time so investigators can strengthen and accelerate their careers, expand expertise, and increase long-term capacity to make major contributions in their field.

2) What is the main goal of this K02 opportunity?

The central goal is to help promising scientists build momentum at a key transition point by providing support that enables deeper research focus. The emphasis is on sustained research concentration rather than short-term project funding alone.

3) Is this award primarily career development support or project funding?

Based on the description provided, this mechanism is framed as career development-style support that prioritizes protected research time and continued research focus, rather than acting only as a short-duration project grant.

4) Is the K02 program standardized across all NIH Institutes and Centers (ICs)?

No. Participating NIH Institutes and Centers may apply their own guidelines and expectations. The description notes that eligibility nuances, budget structures, salary caps, and the amount of research support can differ by IC.

5) Why does it matter which NIH Institute or Center sponsors the K02?

IC-specific provisions can materially affect whether a candidate is a good fit and how an application should be framed. Since guidelines may vary across ICs, aligning with the sponsoring IC's expectations is an important part of planning a competitive application.

6) Should applicants contact NIH program staff before applying?

Yes. Prospective candidates are strongly encouraged to contact the relevant IC program staff listed in the announcement's contacts section before investing significant effort. This is intended to clarify eligibility, confirm alignment with the Institute's mission, and avoid preparing an application that conflicts with IC-specific K02 requirements.

7) What is the role of the applicant organization (institution) in this award?

The applicant organization submits the application on behalf of the candidate and must demonstrate a strong environment for research career development. The institution must also show a concrete commitment to the candidate's growth as an independent scientist and treat the candidate as an integral part of its academic and research program.

8) What does NIH require regarding protected time for the candidate?

A major institutional requirement is protected time. The institution must certify that the candidate will be relieved of other duties sufficiently to devote at least 75 percent effort to the proposed research program.

9) Does the institution need to explain how it will provide protected time?

Yes. The institution must explicitly describe which duties will be reduced or removed to make the 75 percent research effort realistic. This supports the core intent of the award: buying time for deep research concentration rather than adding research on top of an already full workload.

10) What types of organizations are eligible to apply?

Eligibility for applicant organizations is broad within the United States and includes public and state-controlled institutions of higher education, private institutions of higher education, certain nonprofit organizations (with or without 501(c)(3) status), for-profit organizations other than small businesses, and small businesses, along with other entities as described in the full announcement.

11) Are foreign institutions eligible to apply as the applicant organization?

No. Foreign institutions are not eligible to apply. The applicant institution must be domestic, even if the proposed work involves international collaborations.

12) Does this opportunity require cost sharing or matching funds?

No cost sharing or matching requirement is indicated for this opportunity based on the information provided.

13) What scientific or research areas does this FOA cover?

The scope is broad and spans multiple NIH mission domains. Examples listed include environmental health; oral diseases and disorders; deafness and communication disorders; sleep disorders; drug abuse and addiction; mental health research career/scientist development; cardiovascular, lung, and blood diseases; arthritis and musculoskeletal and skin diseases; neurosciences and neurological disorders; allergy, immunology, and transplantation; microbiology and infectious diseases; child health and human development; aging; and vision research.

14) Does the broad scope mean any topic is automatically a fit?

Not necessarily. While the program areas are broad, the exact fit depends heavily on which NIH Institute or Center is sponsoring the award and how the research aligns with that IC's mission and any IC-specific K02 expectations.

15) When was PA-06-527 posted, and what are the key dates shown?

The opportunity was posted on August 16, 2006. Multiple application receipt dates are referenced in the full announcement. The record shows a closing date of January 7, 2009, and an archive date of January 8, 2009.

16) Is PA-06-527 an active funding opportunity today?

The dates shown indicate this specific announcement version is historical (archived in 2009). Anyone seeking a current K02 opportunity would need to confirm whether it has been reissued, replaced, or superseded by a newer NIH funding opportunity announcement and rely on current NIH Guide Notices and active FOAs for up-to-date requirements and deadlines.

17) Where can the full announcement be found?

The full announcement is linked at: http://grants.nih.gov/grants/guide/pa-files/PA-06-527.html.

18) Where can applicants get technical help accessing the announcement online?

NIH's Office of Extramural Research (OER) provides technical help for accessing the announcement online via the OER webmaster contact listed in the record.

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