Opportunity Information: Apply for PA 10 115

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Indo U.S. Vaccine Action Program (VAP) Small Research Grant Program (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Apr 3, 2013 and posted on Feb 26, 2010.
  • Applicants must submit their applications by Apr 3, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments Private institutions of higher education County governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Small businesses Special district governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Indo U.S. Vaccine Action Program (VAP) Small Research Grant Program (R03) is a National Institutes of Health (NIH) discretionary grant opportunity designed to strengthen and expand long-standing vaccine research collaboration between the United States and India. The program traces back to a formal Memorandum of Understanding signed on July 9, 1987, created to build on earlier bilateral science and technology cooperation frameworks such as the Indo-U.S. Science and Technology Subcommission, the Gandhi-Reagan Science and Technology Initiative, the U.S.-India Fund, and the broader Science and Technology Cooperation Agreement. At its core, the VAP aims to support joint vaccine-related research that can ultimately reduce the burden of infectious diseases that matter to India, the U.S., the South Asian region, and global public health.

This specific funding announcement (Funding Opportunity Number PA 10-115) uses the NIH R03 mechanism, which is intended for small, focused research projects. The grant provides U.S. dollar support for vaccine-related research activities carried out in India and the United States and is meant to augment ongoing VAP efforts rather than operate as a standalone clinical trial funding stream. The scientific scope is targeted: applicants are encouraged to propose projects in dengue, influenza (including avian influenza), HIV/AIDS, and tuberculosis, provided the work is conducted through well-established collaborations with Indian investigators. The program is open to a range of vaccine research approaches, including basic research (early-stage discovery and immunology), translational work (bridging lab findings toward product-relevant concepts), clinical research that does not involve trials, and epidemiological studies that inform vaccine development or evaluation strategies. A key limitation is that clinical trials are explicitly not supported under this initiative, meaning proposals should avoid trial implementation and instead focus on preparatory, supporting, or non-trial clinical and population research.

Eligibility is broad and includes many types of U.S. and non-U.S. entities, reflecting the collaborative and international nature of the program. Eligible applicants include state, county, city, township, and special district governments; public and state-controlled universities; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; public housing authorities and Indian housing authorities; for-profit organizations (excluding small businesses in the listed category, though small businesses are also explicitly eligible); independent school districts; and a variety of tribal governments and tribal organizations. The eligibility list also explicitly mentions Alaska Native and Native Hawaiian Serving Institutions, Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities/foreign organizations. Cost sharing or matching is not required, which lowers barriers for applicants who might otherwise need to bring outside funds to participate.

Funding levels and the anticipated number of awards are not fixed because NIH expects applications to vary widely in scope, duration, and cost. As a result, the total dollars awarded and the number of grants made depend on the quantity and quality of submissions, the proposed timelines, and budget reasonableness. The program is categorized under Health and is associated with CFDA 93.856 (Microbiology and Infectious Diseases Research). Key dates in the listing show it was posted February 26, 2010, with later administrative dates indicating it ultimately became archived after the final closing window in 2013. For applicants or institutions seeking more detail, NIH provided the full announcement link (http://grants.nih.gov/grants/guide/pa-files/PA-10-115.html) and directed technical access questions to the NIH Office of Extramural Research (OER) webmaster.

FAQs: Indo U.S. Vaccine Action Program (VAP) Small Research Grant Program (R03) - PA-10-115

What is the Indo U.S. Vaccine Action Program (VAP) Small Research Grant Program (R03)?

The Indo U.S. Vaccine Action Program (VAP) Small Research Grant Program (R03) is an NIH discretionary grant opportunity intended to strengthen and expand vaccine research collaboration between the United States and India through small, focused research projects.

What is the purpose of this grant opportunity?

The purpose is to support joint vaccine-related research that can help reduce the burden of infectious diseases relevant to India, the United States, the South Asian region, and global public health. The program is designed to augment ongoing VAP efforts rather than function as a standalone clinical trial funding stream.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number provided is PA 10-115.

What NIH grant mechanism does this opportunity use?

This opportunity uses the NIH R03 mechanism, which is intended for small, focused research projects.

Does the grant support work in both India and the United States?

Yes. The grant provides U.S. dollar support for vaccine-related research activities carried out in India and the United States, consistent with the program's collaborative U.S.-India focus.

Which diseases or topic areas are specifically encouraged?

Applicants are encouraged to propose vaccine-related projects in dengue, influenza (including avian influenza), HIV/AIDS, and tuberculosis, as long as the work is conducted through well-established collaborations with Indian investigators.

What types of research approaches are within scope for this program?

The scope includes basic research (such as early-stage discovery and immunology), translational work (bridging lab findings toward product-relevant concepts), clinical research that does not involve trials, and epidemiological studies that inform vaccine development or evaluation strategies.

Are clinical trials allowed under this initiative?

No. Clinical trials are explicitly not supported under this initiative. Proposals should avoid clinical trial implementation and instead focus on preparatory, supporting, or non-trial clinical and population research.

Does this program require collaboration with Indian investigators?

Yes. The announcement emphasizes that proposed projects should be conducted through well-established collaborations with Indian investigators.

Who is eligible to apply?

Eligibility is broad and includes many U.S. and non-U.S. entities. The list includes various levels of government (state, county, city, township, special districts), public and state-controlled universities, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), public housing authorities and Indian housing authorities, for-profit organizations, independent school districts, tribal governments and tribal organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities/foreign organizations.

Are specific institution types explicitly mentioned as eligible?

Yes. The eligibility list explicitly mentions Alaska Native and Native Hawaiian Serving Institutions, Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based and community-based organizations and regional organizations.

Are small businesses eligible?

Small businesses are explicitly stated as eligible in the description provided.

Is cost sharing or matching required?

No. Cost sharing or matching is not required.

How much funding is available per award, and how many awards will be made?

Funding levels and the anticipated number of awards are not fixed. NIH expects applications to vary by scope, duration, and cost, so the total dollars awarded and the number of grants depend on the quantity and quality of applications received, proposed timelines, and the reasonableness of budgets.

What is the CFDA number associated with this program?

The program is associated with CFDA 93.856 (Microbiology and Infectious Diseases Research).

What category is this funding opportunity listed under?

This opportunity is categorized under Health.

When was this opportunity posted, and what is its current status?

The listing indicates it was posted on February 26, 2010, and later administrative information indicates it ultimately became archived after the final closing window in 2013.

Where can applicants find the full funding announcement?

NIH provided the full announcement link here: http://grants.nih.gov/grants/guide/pa-files/PA-10-115.html

Who should be contacted for technical access issues with the announcement?

Technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster.

What is the historical background of the VAP collaboration?

The program traces back to a formal Memorandum of Understanding signed on July 9, 1987, and was created to build on earlier bilateral science and technology cooperation frameworks, including the Indo-U.S. Science and Technology Subcommission, the Gandhi-Reagan Science and Technology Initiative, the U.S.-India Fund, and the broader Science and Technology Cooperation Agreement.

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