Opportunity Information: Apply for PA 12 114

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Infrastructure Development Program in Patient Centered Outcomes Research (PCOR) (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Jun 11, 2014 and posted on Feb 23, 2012.
  • Applicants must submit their applications by Jun 11, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • Eligible applicants include: State governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Faith based or Community based Organizations Indian/Native American Tribal Governments (Other than Federally Recognized).
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Opportunity Summary:

The Infrastructure Development Program in Patient Centered Outcomes Research (PCOR) (R24) is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ) designed to strengthen the practical infrastructure needed to generate, translate, and spread patient-centered outcomes research. The central aim is to improve health outcomes by helping organizations build resources that develop and disseminate evidence-based information that real decision-makers can use, including patients, clinicians, policymakers, and health care administrators. The focus is on answering applied questions that these groups explicitly care about, especially questions around which clinical interventions and health system design approaches work best, for which patients, and under what specific circumstances. In other words, the program is less about funding a single clinical study and more about creating the tools, resources, methods, platforms, or other enabling supports that make PCOR more usable and more responsive to stakeholder needs.

This funding announcement uses the AHRQ Resource-Related Research Project (R24) mechanism, which is typically intended for projects that create shared resources, infrastructure, or capabilities that support research and real-world uptake of findings. Applicants are expected to propose work that meaningfully improves the ability to produce and distribute actionable evidence, such as developing knowledge dissemination systems, stakeholder-informed decision supports, data or analytic resources, collaborative networks, or other structured capacity that helps translate research into practice. The emphasis on dissemination and responsiveness to expressed needs signals that AHRQ is looking for infrastructure that connects evidence to end users, rather than evidence that sits on a shelf.

Funding levels and the number of awards are not fixed because AHRQ anticipates that project scope will vary by applicant and by the type of infrastructure being proposed. The posting indicates an estimated total funding amount of $1,000,000 and an award ceiling of $250,000, but the agency notes that actual awards depend on the number of high-quality, meritorious applications received, the duration and costs proposed, and the availability of funds at the time of award. No cost sharing or matching is required, which can lower barriers for organizations that do not have significant non-federal resources to commit.

Eligibility is broad and includes state governments, public and state-controlled institutions of higher education, private institutions of higher education, and Native American tribal governments (federally recognized), as well as Native American tribal organizations that are not federally recognized. The opportunity also allows additional eligible applicants such as eligible federal agencies and faith-based or community-based organizations, reflecting the program's interest in reaching diverse settings where patient-centered outcomes evidence is created, implemented, and used. This breadth makes sense for PCOR infrastructure, because effective dissemination and implementation often require partnerships across academia, health systems, community organizations, and governmental entities.

Administratively, the opportunity is identified as Funding Opportunity Number PA-12-114, categorized under the health funding activity area, with CFDA number 93.226 (Research on Healthcare Costs, Quality and Outcomes). Key dates listed in the record include a posted date of February 23, 2012, an original closing date of December 19, 2014, and an archive date of July 11, 2014 (indicating the listing is historical/archived). The full announcement was hosted through the NIH grants guide (as AHRQ opportunities are often distributed via NIH systems), and the contact provided for access or linking problems is the NIH Office of Extramural Research (OER) webmaster.

In practical terms, a strong application under this FOA would be expected to clearly define the infrastructure gap it intends to fill, demonstrate how patients and other end users have expressed the need for the proposed resource, and show how the resulting products or capabilities will be disseminated and adopted to improve decision-making and outcomes. Competitive proposals would typically make a convincing case that what is being built will be broadly useful beyond a single site or project, will be grounded in evidence-based methods, and will accelerate the ability of stakeholders to choose the most effective clinical and health system interventions for specific patient populations and contexts.

Infrastructure Development Program in Patient Centered Outcomes Research (PCOR) (R24) - FAQs

What is this grant opportunity?

The Infrastructure Development Program in Patient Centered Outcomes Research (PCOR) (R24) is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ). It is designed to strengthen the practical infrastructure needed to generate, translate, and spread patient-centered outcomes research (PCOR).

What is the main goal of the program?

The central aim is to improve health outcomes by helping organizations build resources that develop and disseminate evidence-based information that real decision-makers can use. These decision-makers include patients, clinicians, policymakers, and health care administrators.

What kinds of questions is PCOR infrastructure expected to support?

The program emphasizes applied questions that end users explicitly care about, especially questions such as which clinical interventions and health system design approaches work best, for which patients, and under what specific circumstances.

Is this funding mainly for conducting a single clinical study?

No. The program is described as being less about funding a single clinical study and more about creating tools, resources, methods, platforms, or other enabling supports that make PCOR more usable and more responsive to stakeholder needs.

What grant mechanism does this opportunity use?

This funding announcement uses the AHRQ Resource-Related Research Project (R24) mechanism, which is typically intended for projects that create shared resources, infrastructure, or capabilities that support research and real-world uptake of findings.

What types of projects are encouraged under the R24 mechanism for this FOA?

Applicants are expected to propose work that meaningfully improves the ability to produce and distribute actionable evidence. Examples described include developing knowledge dissemination systems, stakeholder-informed decision supports, data or analytic resources, collaborative networks, or other structured capacity that helps translate research into practice.

What is AHRQ emphasizing in terms of impact?

The emphasis is on dissemination and responsiveness to expressed needs. AHRQ is looking for infrastructure that connects evidence to end users rather than evidence that remains unused.

How much funding is available?

The posting indicates an estimated total funding amount of $1,000,000, with an award ceiling of $250,000. However, the funding levels and number of awards are not fixed because AHRQ anticipates that project scope will vary by applicant and by the type of infrastructure being proposed.

Are award amounts guaranteed?

No. The agency notes that actual awards depend on the number of high-quality, meritorious applications received, the duration and costs proposed, and the availability of funds at the time of award.

Is cost sharing or matching required?

No. No cost sharing or matching is required.

Who is eligible to apply?

Eligibility is broad and includes state governments, public and state-controlled institutions of higher education, private institutions of higher education, and Native American tribal governments (federally recognized), as well as Native American tribal organizations that are not federally recognized.

Are community-based or faith-based organizations eligible?

Yes. The opportunity allows additional eligible applicants such as faith-based or community-based organizations.

Can federal agencies apply?

Yes. The opportunity also allows additional eligible applicants such as eligible federal agencies.

Why is eligibility so broad?

The breadth reflects the program's interest in reaching diverse settings where patient-centered outcomes evidence is created, implemented, and used. The description notes that effective dissemination and implementation often require partnerships across academia, health systems, community organizations, and governmental entities.

What is the Funding Opportunity Number for this program?

The opportunity is identified as Funding Opportunity Number PA-12-114.

What is the CFDA number and program area?

The CFDA number is 93.226, titled Research on Healthcare Costs, Quality and Outcomes, and it is categorized under the health funding activity area.

When was this opportunity posted and when did it close?

Key dates listed include a posted date of February 23, 2012, and an original closing date of December 19, 2014.

Is this funding opportunity still active?

The record lists an archive date of July 11, 2014, indicating the listing is historical/archived.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guide (AHRQ opportunities are often distributed via NIH systems).

Who is listed as the contact for access or linking problems?

The contact provided for access or linking problems is the NIH Office of Extramural Research (OER) webmaster.

What would a strong application be expected to include?

A strong application would be expected to clearly define the infrastructure gap it intends to fill, demonstrate how patients and other end users have expressed the need for the proposed resource, and show how the resulting products or capabilities will be disseminated and adopted to improve decision-making and outcomes.

What characteristics are associated with competitive proposals?

Competitive proposals would typically make a convincing case that what is being built will be broadly useful beyond a single site or project, will be grounded in evidence-based methods, and will accelerate the ability of stakeholders to choose the most effective clinical and health system interventions for specific patient populations and contexts.

What does "infrastructure" mean in the context of this program?

In this context, infrastructure refers to practical enabling supports that help produce, translate, disseminate, and support uptake of patient-centered outcomes evidence. The description highlights tools, resources, methods, platforms, knowledge dissemination systems, decision supports, data/analytic resources, and collaborative networks as examples of the kinds of infrastructure that can make PCOR more usable in real-world decision-making.

Does this program prioritize end-user needs?

Yes. The program stresses responsiveness to expressed needs from real decision-makers, including patients, clinicians, policymakers, and health care administrators.

What is the overall purpose of building PCOR infrastructure?

The purpose is to improve decision-making and health outcomes by ensuring that evidence-based information is developed and disseminated in a way that stakeholders can actually use, particularly when choosing clinical interventions and health system approaches that work best for specific patients and circumstances.

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