Opportunity Information: Apply for PAR 09 221
Apply for PAR 09 221
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.389 National Center for Research Resources 93.396 Cancer Biology Research 93.839 Blood Diseases and Resources Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.859 Biomedical Research and Research Training 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
- This funding opportunity was created on Aug 22, 2012 and posted on Aug 5, 2009.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42) is a National Institutes of Health (NIH) funding opportunity designed for small business concerns that want to build and test new computing-driven approaches that can accelerate biomedical research. The central idea behind the program is that modern biomedical science is increasingly limited not just by experiments, but by the ability to manage, integrate, analyze, and interpret rapidly growing volumes of complex data, and by the need for better computational models that can explain or predict biological behavior. Through this FOA, NIH is looking to support practical, innovative computational tools and methods that directly enable faster progress in areas of strong biomedical opportunity.
The scientific scope is broad within biomedical informatics and computational biology, and it covers both applied informatics tool-building and deeper computational research. On the informatics and technology side, it includes work such as database design and architecture, new or improved graphical user interfaces, better ways to query and retrieve data, and tools for data visualization, manipulation, and exploration. It also explicitly emphasizes data integration, particularly through integrated analytical tools that can pull together multiple data types or sources and make them useful in a unified workflow. In addition, the program highlights tools that support electronic collaboration, reflecting the reality that biomedical research teams are often distributed and need platforms that help them share data, analyses, and results efficiently. On the computational biology side, it supports development of computational models and simulations, including structural, functional, integrative, and analytical models, as well as methods that help researchers understand biological processes through computation rather than only through wet-lab experimentation.
The funding mechanism is the Small Business Technology Transfer (STTR) program using the R41/R42 award types. That means projects are expected to be carried out by a small business in formal partnership with a research institution, with the goal of transferring and translating scientific or technical innovation into a product, platform, or capability that can be used in biomedical research settings. The FOA allows Phase I applications (generally focused on feasibility and proof-of-concept), Phase II applications (focused on full research and development and maturation of the technology), and Fast Track applications (a combined Phase I/Phase II pathway intended to speed transition when there is a clear plan and strong preliminary basis).
This opportunity runs in parallel with other NIH announcements that share the same overall scientific scope but use different grant mechanisms depending on the applicant type and project style. In particular, it aligns with an SBIR companion FOA (R43/R44) for small businesses pursuing innovation without the STTR partnership structure, and it is also positioned alongside NIH research grant options that are not small-business-specific, including an R21 pathway for higher-risk, higher-reward exploratory work and an R01 pathway for more traditional, fully developed research programs. Taken together, these parallel announcements signal that NIH is trying to stimulate the same general area of biomedical computational innovation through multiple routes, depending on who is leading the work and what stage the idea is in.
Administratively, the opportunity is listed as a discretionary grant in the health and education activity categories, with eligibility limited to small businesses. It does not require cost sharing or matching funds. The opportunity is identified as PAR-09-221, was originally posted on August 5, 2009, and remained open through a multi-year window with closing dates extending into 2013, after which it was archived. It is associated with a wide range of NIH program areas, reflected in the CFDA listings spanning fields such as human genome research, cancer biology, neuroscience, aging, vision, substance use research, and general biomedical research infrastructure. This breadth reinforces the idea that NIH is not limiting the program to one disease area; instead, it is funding computational innovations that can broadly enable or transform biomedical research across many domains.
Frequently Asked Questions (FAQs)
What is the Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42)?
It is an NIH funding opportunity for small business concerns to build and test new computing-driven approaches that can accelerate biomedical research. The program focuses on practical, innovative computational tools, methods, and models that help researchers manage, integrate, analyze, and interpret rapidly growing and complex biomedical data, and that improve the ability to explain or predict biological behavior through computation.
Who is this funding opportunity intended for?
Eligibility is limited to small businesses. Because it uses the STTR program mechanism, projects are expected to be led by a small business working in a formal partnership with a research institution.
What NIH mechanism does this opportunity use?
This opportunity uses the Small Business Technology Transfer (STTR) program mechanism with R41/R42 award types.
What kinds of projects does NIH want to support through this FOA?
NIH is looking to support practical and innovative computational tools and methods that directly enable faster progress in areas of strong biomedical opportunity. The scope is broad across biomedical informatics and computational biology, including both applied tool-building and deeper computational research.
What is the main problem this program is trying to address?
The FOA is built around the idea that modern biomedical science is increasingly limited by the ability to manage, integrate, analyze, and interpret rapidly growing volumes of complex data, and by the need for better computational models that can explain or predict biological behavior (not only by the ability to run experiments).
What is included on the biomedical informatics and technology side of the scope?
Examples named in the opportunity include database design and architecture, new or improved graphical user interfaces, improved approaches for querying and retrieving data, and tools for data visualization, manipulation, and exploration.
Does the opportunity emphasize data integration?
Yes. It explicitly emphasizes data integration, particularly through integrated analytical tools that can pull together multiple data types or data sources and make them useful within a unified workflow.
Are electronic collaboration tools within scope?
Yes. The program highlights tools that support electronic collaboration, reflecting that biomedical research teams are often distributed and need platforms that help them share data, analyses, and results efficiently.
What is included on the computational biology side of the scope?
The FOA supports development of computational models and simulations, including structural, functional, integrative, and analytical models, as well as methods that help researchers understand biological processes through computation rather than only through wet-lab experimentation.
What are the phases available under this STTR opportunity?
The FOA allows Phase I, Phase II, and Fast Track applications. Phase I is generally focused on feasibility and proof-of-concept. Phase II is focused on full research and development and maturation of the technology. Fast Track combines Phase I and Phase II to speed transition when there is a clear plan and strong preliminary basis.
What is the goal of using the STTR mechanism for these projects?
Projects are expected to be carried out by a small business in formal partnership with a research institution, with the goal of transferring and translating scientific or technical innovation into a product, platform, or capability that can be used in biomedical research settings.
Is this opportunity limited to one disease area or biomedical domain?
No. The program is positioned as broadly enabling across many biomedical domains. The breadth is reinforced by the wide range of NIH program areas and CFDA listings associated with it, spanning fields such as human genome research, cancer biology, neuroscience, aging, vision, substance use research, and general biomedical research infrastructure.
How does this STTR FOA relate to other NIH opportunities in the same scientific space?
This opportunity runs in parallel with other NIH announcements that share the same overall scientific scope but use different mechanisms. It aligns with an SBIR companion FOA (R43/R44) for small businesses pursuing innovation without the STTR partnership structure, and it is also positioned alongside non-small-business NIH research grant options such as R21 (exploratory, higher-risk/higher-reward) and R01 (more traditional, fully developed research programs).
What is the identifier for this funding opportunity?
The opportunity is identified as PAR-09-221.
When was this opportunity posted, and is it still open?
It was originally posted on August 5, 2009. It remained open through a multi-year window with closing dates extending into 2013, after which it was archived.
What type of grant is it listed as?
It is listed as a discretionary grant in the health and education activity categories.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching funds.
What kinds of outcomes or deliverables does NIH seem to be aiming for?
Based on the STTR structure and the stated goals, the FOA is aiming for innovations that can be translated into practical products, platforms, capabilities, tools, methods, or models that are usable in biomedical research settings and that speed research progress by improving computation around biomedical data and modeling.
Browse more opportunities from the same agency: National Institutes of Health
Browse more opportunities from the same category: Education Health
Next opportunity: NEA Literature Translation Projects Fellowships, FY2011
Previous opportunity: Innovations in Biomedical Computational Science and Technology Initiative (SBIR R43/R44)
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 09 221) also looked into and applied for these:
| Funding Opportunity |
|---|
| Optimization of Small Molecule Probes for the Nervous System (R21) Apply for PAR 09 251 Funding Number: PAR 09 251 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Image guided Drug Delivery in Cancer (R01) Apply for PA 09 253 Funding Number: PA 09 253 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Biology of Estrogen Receptor Negative Breast Cancer in Various Racial and Ethnic Groups (U01) Apply for RFA CA 09 026 Funding Number: RFA CA 09 026 Agency: National Institutes of Health Category: Education Health Funding Amount: $667,000 |
| Nutrition and Physical Activity Research to Promote Cardiovascular and Pulmonary Health (R01) Apply for PA 09 243 Funding Number: PA 09 243 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Nutrition and Physical Activity Research to Promote Cardiovascular and Pulmonary Health (R21) Apply for PA 09 244 Funding Number: PA 09 244 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Optimization of Small Molecule Probes for the Nervous System (STTR R41) Apply for PAR 09 259 Funding Number: PAR 09 259 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Optimization of Small Molecule Probes for the Nervous System (SBIR R43) Apply for PAR 09 260 Funding Number: PAR 09 260 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Institutional Clinical and Translational Science Award (U54) Apply for RFA RM 09 019 Funding Number: RFA RM 09 019 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Limited Competition for Research Centers in Minority Institutions Infrastructure for Clinical and Translational Research (RCTR) U54 Apply for PAR 09 261 Funding Number: PAR 09 261 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploring Epigenomic Processes and Non Coding RNAs in HIV/AIDS (R01) Apply for RFA DA 10 010 Funding Number: RFA DA 10 010 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
| Exploring Epigenomic Processes and Non Coding RNAs in HIV/AIDS (R21) Apply for RFA DA 10 011 Funding Number: RFA DA 10 011 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Targeted Library Synthesis and Screening at Novel Targets for Potential Drug Addiction Treatments and Research Tools (R21/R33) Apply for RFA DA 10 005 Funding Number: RFA DA 10 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) Apply for RFA GM 10 009 Funding Number: RFA GM 10 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Developing Research Capacity in Africa for Studies on HIV Associated Malignancies (D43) Apply for RFA CA 09 016 Funding Number: RFA CA 09 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Medications Development for Cannabis Related Disorders (R01) Apply for RFA DA 10 016 Funding Number: RFA DA 10 016 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Specialized Programs of Research Excellence (SPOREs) in Human Cancer for Years 2010, 2011 and 2012 (P50) Apply for PAR 10 003 Funding Number: PAR 10 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Discovery for Nervous System Disorders (R21) Apply for PAR 10 002 Funding Number: PAR 10 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Drug Discovery for Nervous System Disorders (R01) Apply for PAR 10 001 Funding Number: PAR 10 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Community Networks Program (CNP) Centers for Reducing Cancer Disparities through Outreach, Research and Training (U54) Apply for RFA CA 09 032 Funding Number: RFA CA 09 032 Agency: National Institutes of Health Category: Education Health Funding Amount: $900,000 |
| Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00) Apply for RFA CA 09 015 Funding Number: RFA CA 09 015 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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