Opportunity Information: Apply for RFA GH 15 0060102SUPP16
Apply for RFA GH 15 0060102SUPP16
- The HHS-CDC-HHSCDCERA in the health sector is offering a public funding opportunity titled "Institutional Research Collaboration between the Liverpool School of Tropical Medicine and the Centers for Disease Control and Prevention" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.326.
- This funding opportunity was created on Dec 22, 2015 and posted on Dec 22, 2015.
- Applicants must submit their applications by Feb 23, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
This grant opportunity, titled "Institutional Research Collaboration between the Liverpool School of Tropical Medicine and the Centers for Disease Control and Prevention," is a CDC-funded cooperative agreement focused on strengthening applied malaria work through an ongoing institutional partnership. It is structured as a continuation award rather than a new open competition, meaning it is intended to support and extend existing collaboration and activities already underway between the named institutions rather than broadly fund a large pool of new applicants. The award mechanism is a cooperative agreement, which typically implies substantial involvement from the funding agency in planning, implementation, and oversight, reflecting a hands-on partnership model rather than a standard grant where the recipient operates more independently.
The core purpose centers on three connected objectives that target practical, program-relevant malaria challenges in sub-Saharan Africa and Asia. First, it aims to conduct operations research in malaria, which generally refers to research embedded in real-world program settings to improve how interventions are delivered, adopted, and scaled. This type of work often examines questions such as how to optimize bed net distribution, improve diagnostic and treatment pathways, strengthen supply chains for antimalarials and rapid diagnostic tests, or refine strategies for reaching high-risk and underserved populations. The emphasis on sub-Saharan Africa and Asia reflects regions with significant malaria burden and diverse transmission contexts, where evidence from implementation settings can directly inform program decisions.
Second, the opportunity supports establishing or strengthening monitoring and evaluation systems for malaria program activities, including those supported by the U.S. President's Malaria Initiative (PMI). In practical terms, this objective is about building the data and evaluation infrastructure needed to track program performance and outcomes. That can include defining indicators, improving routine health information systems, supporting survey design and analysis, enhancing data quality assurance processes, and helping programs use results for decision-making. Strong monitoring and evaluation is often a prerequisite for understanding whether interventions are reaching intended populations, whether resources are being used efficiently, and how strategies should be adapted over time as transmission patterns shift.
Third, the grant emphasizes creating feasible and effective opportunities to integrate malaria efforts with other child survival, vector control, and infectious disease programs. This reflects the reality that communities and health systems often face multiple overlapping health threats, and that coordinated delivery can reduce duplication, improve coverage, and strengthen overall primary health services. Integration might involve aligning malaria case management with broader child health services, coordinating vector control activities that affect multiple mosquito-borne diseases, or leveraging shared community health worker networks, surveillance systems, and health communication platforms. The focus on feasibility signals an interest in approaches that can realistically be implemented within existing program constraints, budgets, and health system capacity.
In addition to supporting ongoing research and collaboration, the funding explicitly includes evaluation of the efficacy and safety of the PfSPZ vaccine. PfSPZ is a malaria vaccine approach based on Plasmodium falciparum sporozoites, and evaluating both efficacy (how well it prevents infection or disease) and safety (adverse events and tolerability) is essential for determining its potential programmatic role. Including this component indicates that the collaboration is not only focused on operational improvements to current malaria control efforts but is also positioned to contribute to the evidence base for new tools that could change future malaria prevention strategies.
From an administrative standpoint, the opportunity is listed under CFDA 93.326 (a CDC assistance listing associated with malaria-related work), with the agency identified as HHS-CDC. It was posted and created on December 22, 2015, with a closing date of February 23, 2016. The listing notes an expectation of a single award and provides an award ceiling of 0, which often appears in continuation or supplement postings where the funding amount may be determined through internal allocation or handled through associated award documentation rather than a publicly stated maximum. Eligibility is described as "Others (see text field entitled Additional Information on Eligibility for clarification)," which is typical of opportunities tied to specific institutional collaborations or restricted continuation mechanisms.
Overall, this funding opportunity is best understood as a targeted continuation cooperative agreement designed to sustain a CDC-Liverpool School of Tropical Medicine partnership that combines applied malaria operations research, strengthened monitoring and evaluation for malaria programs (including PMI-supported activities), integrated approaches across related public health programs, and specific vaccine-related evaluation work focused on the PfSPZ candidate.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Institutional Research Collaboration between the Liverpool School of Tropical Medicine and the Centers for Disease Control and Prevention."
Which agency is funding and administering this opportunity?
The opportunity is funded and administered by HHS-CDC (the Centers for Disease Control and Prevention within the U.S. Department of Health and Human Services).
What type of funding mechanism is being used?
This opportunity uses a cooperative agreement mechanism. A cooperative agreement typically involves substantial involvement from the funding agency in planning, implementation, and oversight, reflecting a more hands-on partnership model than many standard grants.
Is this an open competition for new applicants?
No. The opportunity is described as a continuation award rather than a new open competition. It is intended to support and extend collaboration and activities already underway between the named institutions, rather than funding a broad pool of new applicants.
Who is the collaboration between?
The collaboration is between the Liverpool School of Tropical Medicine and the Centers for Disease Control and Prevention (CDC).
What is the overall purpose of the award?
The overall purpose is to strengthen applied malaria work through an ongoing institutional partnership, with activities centered on operations research, monitoring and evaluation systems, and integration of malaria efforts with other related public health programs. The funding also explicitly includes evaluation of the efficacy and safety of the PfSPZ malaria vaccine candidate.
What are the main objectives of the project?
The opportunity describes three connected objectives focused on practical, program-relevant malaria challenges in sub-Saharan Africa and Asia:
- Conduct operations research in malaria in real-world program settings to improve how interventions are delivered, adopted, and scaled.
- Establish or strengthen monitoring and evaluation systems for malaria program activities, including those supported by the U.S. President's Malaria Initiative (PMI).
- Create feasible and effective opportunities to integrate malaria efforts with other child survival, vector control, and infectious disease programs.
What does "operations research" mean in the context of this opportunity?
Operations research here refers to research embedded in real-world program settings aimed at improving implementation and performance of malaria interventions. The description highlights program-relevant questions such as optimizing bed net distribution, improving diagnostic and treatment pathways, strengthening supply chains for antimalarials and rapid diagnostic tests, and refining strategies to reach high-risk and underserved populations.
Which geographic regions are emphasized for the work?
The work emphasizes sub-Saharan Africa and Asia, reflecting regions with significant malaria burden and diverse transmission contexts where implementation evidence can inform program decisions.
What monitoring and evaluation (M&E) activities are supported?
The opportunity supports establishing or strengthening monitoring and evaluation systems for malaria program activities. Examples described include defining indicators, improving routine health information systems, supporting survey design and analysis, enhancing data quality assurance processes, and helping programs use results for decision-making.
How does the opportunity relate to the U.S. President's Malaria Initiative (PMI)?
The monitoring and evaluation objective explicitly includes malaria program activities supported by PMI, indicating that M&E strengthening may be applied to PMI-supported efforts as part of the collaboration.
What does "integration" mean in this award?
Integration refers to coordinating malaria efforts with other child survival, vector control, and infectious disease programs to reduce duplication, improve coverage, and strengthen services. Examples described include aligning malaria case management with broader child health services, coordinating vector control activities that impact multiple mosquito-borne diseases, and leveraging shared community health worker networks, surveillance systems, and health communication platforms.
Why does the opportunity emphasize "feasible" integration approaches?
The description signals interest in integration approaches that can realistically be implemented within existing program constraints, budgets, and health system capacity.
Does the opportunity include vaccine-related work?
Yes. The funding explicitly includes evaluation of the efficacy and safety of the PfSPZ vaccine.
What is the PfSPZ vaccine, as described in the opportunity?
PfSPZ is described as a malaria vaccine approach based on Plasmodium falciparum sporozoites. The opportunity emphasizes evaluating both efficacy (how well it prevents infection or disease) and safety (adverse events and tolerability) to determine its potential programmatic role.
How many awards are expected?
The listing notes an expectation of a single award.
What is the CFDA (Assistance Listing) number for this opportunity?
The opportunity is listed under CFDA 93.326, which is associated with CDC malaria-related assistance.
When was the opportunity posted and what were the key dates?
It was posted and created on December 22, 2015, with a closing date of February 23, 2016.
What is the award ceiling for this opportunity?
The listing provides an award ceiling of 0. The description notes that this often appears in continuation or supplement postings where the funding amount may be determined through internal allocation or associated award documentation rather than a publicly stated maximum.
What is stated about eligibility?
Eligibility is described as "Others (see text field entitled Additional Information on Eligibility for clarification)." This type of eligibility phrasing is described as typical of opportunities tied to specific institutional collaborations or restricted continuation mechanisms.
How should this opportunity be understood overall?
It is best understood as a targeted continuation cooperative agreement designed to sustain a CDC-Liverpool School of Tropical Medicine partnership combining applied malaria operations research, strengthened monitoring and evaluation (including PMI-supported activities), integrated approaches across related public health programs, and specific PfSPZ vaccine efficacy and safety evaluation work.
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