Opportunity Information: Apply for RFA GM 14 014
Apply for RFA GM 14 014
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Instrument Development for Biomedical Applications (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Oct 18, 2013 and posted on Jul 10, 2013.
- Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $175,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Native American tribal governments (Federally recognized) County governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities City or township governments Special district governments Public and State controlled institutions of higher education Independent school districts Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Instrument Development for Biomedical Applications (R21) opportunity (Funding Opportunity Number RFA-GM-14-014) is a discretionary NIH grant program run through the National Institute of General Medical Sciences (NIGMS). Its core purpose is to support early stage, innovative work that creates new instruments or meaningfully improves existing instrumentation used in biomedical research. The emphasis is on building broadly useful tools that many biomedical or clinical research groups could adopt, rather than instruments tailored to a single disease area, organ system, or narrowly defined research niche. In practice, this means proposals are expected to focus on enabling technologies, platforms, or methods with clear potential to generalize across multiple fields and applications in biomedicine.
This funding opportunity uses the NIH R21 activity code, which is typically geared toward exploratory and developmental projects. The R21 mechanism is generally used when the work is high impact and innovative but still at a stage where preliminary data may be limited, and where the project goals are about proof of concept, prototyping, feasibility testing, or demonstrating key performance improvements. For an instrument development project, that often translates into designing and building a prototype, validating core technical specifications, showing that the instrument performs as intended in relevant biomedical settings, and establishing that the tool is likely to be adoptable by other researchers. NIGMS interest here is not just incremental refinement, but instrumentation advances that could change what researchers can measure, manipulate, image, analyze, or automate in a way that is broadly enabling.
The announcement lists an estimated total funding level of about $2,000,000 for the opportunity and an award ceiling of $175,000 (as provided in the source information). It also specifies that there is no cost sharing or matching requirement, meaning applicants are not required to commit non-federal funds as a condition of receiving an award. The program falls under CFDA number 93.859, Biomedical Research and Research Training, which is NIGMS standard territory for supporting foundational tools and methods that serve the wider biomedical research enterprise.
Eligibility is expansive and includes many types of U.S. and non-U.S. organizations. Domestic applicants can include public and private institutions of higher education, public and state-controlled universities, private universities, independent school districts, state and local governments (including county, city or township, special district governments), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofits (including 501(c)(3) and certain non-501(c)(3) nonprofits), and for-profit entities including small businesses. The notice also explicitly allows applications from foreign organizations and foreign institutions, permits non-U.S. components of U.S. organizations to apply, and allows foreign components as defined in NIH policy. It further highlights categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, reinforcing that NIGMS is open to a wide range of institutional settings as long as the proposed work aligns with the instrumentation development goals.
Key dates in the source record show the opportunity was posted July 10, 2013, with an original closing date of October 10, 2013, later updated to a current closing date of November 1, 2013, and an archive date of December 1, 2013. While these dates indicate the specific solicitation cycle is historical, the summary still captures what NIGMS was seeking: creative, generalizable instrument development projects positioned to benefit a broad community of biomedical researchers.
Applicants looking for the full official details were directed to the NIH Grants Guide posting at http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-014.html. For technical issues accessing or linking to the announcement, the listed point of contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is a standard support contact for NIH funding announcement access problems.
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled "Instrument Development for Biomedical Applications (R21)" and is identified by Funding Opportunity Number RFA-GM-14-014.
Which federal agency and institute run this program?
This is an NIH grant opportunity administered through the National Institute of General Medical Sciences (NIGMS).
What is the main purpose of this grant?
The core purpose is to support early-stage, innovative work that creates new instruments or meaningfully improves existing instrumentation used in biomedical research.
What kinds of projects does NIGMS want to fund under this announcement?
Projects are expected to focus on enabling technologies, platforms, or methods that are broadly useful across biomedical or clinical research, rather than tools designed for a single disease area, one organ system, or a narrow research niche.
What does "broadly useful" mean in practice for an instrument proposal?
It means the instrument should have clear potential for adoption by many biomedical or clinical research groups, with applicability that generalizes across multiple fields and applications in biomedicine.
What grant mechanism (activity code) does this opportunity use?
This opportunity uses the NIH R21 activity code, which is typically used for exploratory and developmental research projects.
What is the R21 mechanism typically used for?
The R21 mechanism is generally used when the work is innovative and potentially high impact, but still at a stage where preliminary data may be limited, and the goals center on proof of concept, prototyping, feasibility testing, or demonstrating key performance improvements.
For instrument development specifically, what kinds of activities fit the R21 scope described here?
Examples described include designing and building a prototype, validating core technical specifications, demonstrating that the instrument performs as intended in relevant biomedical settings, and establishing that the tool is likely to be adoptable by other researchers.
Is this opportunity intended for incremental tweaks to existing tools?
The emphasis described is not on incremental refinement, but on instrumentation advances that could significantly expand what researchers can measure, manipulate, image, analyze, or automate in broadly enabling ways.
How much total funding was estimated for this opportunity?
The source record lists an estimated total funding level of about $2,000,000.
What is the award ceiling listed in the source information?
The award ceiling listed is $175,000 (as provided in the source information).
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement, meaning applicants are not required to commit non-federal funds as a condition of receiving an award.
What is the CFDA number associated with this program?
The program falls under CFDA 93.859, Biomedical Research and Research Training.
Who is eligible to apply?
Eligibility is described as expansive and includes many types of U.S. and non-U.S. organizations, as long as the proposed work aligns with the instrumentation development goals.
What types of U.S. organizations are listed as eligible?
Domestic eligible applicants listed include public and private institutions of higher education (including public/state-controlled universities and private universities), independent school districts, state and local governments (including county, city or township, and special district governments), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, nonprofits (including 501(c)(3) and certain non-501(c)(3) nonprofits), and for-profit entities including small businesses.
Are foreign organizations or institutions allowed to apply?
Yes. The notice explicitly allows applications from foreign organizations and foreign institutions.
Can a U.S. organization apply if the work involves non-U.S. components?
Yes. The notice permits non-U.S. components of U.S. organizations to apply and allows foreign components as defined in NIH policy.
Does the announcement highlight any specific institution types as encouraged or included?
It explicitly notes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
When was the opportunity posted and when did it close?
The source record shows it was posted on July 10, 2013. The original closing date was October 10, 2013, later updated to a current closing date of November 1, 2013.
Is this funding opportunity still active?
The record includes an archive date of December 1, 2013. Based on the dates provided, the specific solicitation cycle described is historical.
Where can applicants find the full official announcement text?
The full official details were directed to the NIH Grants Guide posting at: http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-14-014.html.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing or linking to the announcement, the listed point of contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What is the overall scientific emphasis of NIGMS in this opportunity?
The emphasis is on instrumentation advances that are broadly enabling for biomedical research communities, supporting foundational tools and methods that many research groups could adopt.
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