Opportunity Information: Apply for RFA DA 16 011

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Integration of Infectious Diseases and Substance Abuse Intervention Services for Individuals Living with HIV (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279,.
  • This funding opportunity was created on Dec 07, 2015 and posted on Dec 07, 2015.
  • Applicants must submit their applications by Mar 02, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA DA 16 011

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Opportunity Summary:

The Integration of Infectious Diseases and Substance Abuse Intervention Services for Individuals Living with HIV (R01) funding opportunity (RFA-DA-16-011) is a discretionary NIH grant program, listed under CFDA 93.279, focused on improving health outcomes for people living with HIV (PLWH) who also have substance use disorders and other co-occurring conditions. The central idea is that many patients move between HIV clinics, addiction treatment programs, and other medical or behavioral health services, and gaps between these systems often lead to worse outcomes. This FOA aims to fund research that does not just test individual-level treatments, but instead develops and evaluates organizational and systems-level interventions that make care more integrated, higher quality, sustainable over time, and cost-effective in real-world settings.

A major emphasis of the FOA is on multidisciplinary research designed to improve how evidence-based practices are adopted and implemented across service systems. On the HIV care side, the announcement seeks projects that strengthen the routine use of evidence-based substance use screening and treatment within HIV centers and closely related medical settings. This includes building and testing practical approaches for integrating substance use identification and treatment into the workflows, staffing models, referral pathways, and clinical decision processes that HIV clinics already use. On the addiction treatment side, the FOA supports projects that increase the uptake and integration of effective HIV care within addiction treatment settings. That includes interventions that improve linkage to HIV care, long-term retention in HIV care, and adherence to antiretroviral therapy, recognizing that sustained engagement and medication adherence are critical to viral suppression and long-term health.

The FOA also explicitly encourages integration efforts that address comorbid conditions commonly seen alongside HIV and substance use disorders. Applicants are encouraged to incorporate strategies that improve access to and coordination of care for co-infections and psychiatric disorders, among other conditions. The overall goal is to develop models of care that reflect the complexity of patients lives and clinical needs, rather than treating HIV, addiction, and other conditions in isolation. In practice, this could involve coordinated care pathways, shared care protocols, cross-training of staff, use of implementation supports, and system redesign approaches that reduce fragmentation between infectious disease services, addiction treatment, and behavioral health care.

In terms of eligibility, the opportunity is broadly open to a wide range of applicants, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other entities as allowed under the additional eligibility language. The sponsoring agency is HHS, National Institutes of Health (NIH). The FOA was posted on December 7, 2015, with a closing date of March 2, 2016.

Taken together, this R01 opportunity is aimed at producing evidence on how to restructure and improve service delivery systems so that HIV treatment and substance use services are not parallel tracks, but coordinated, integrated, and easier for patients to navigate. The intended outcome is stronger implementation of proven interventions in the settings where people actually receive care, leading to better engagement, better adherence, improved management of co-occurring conditions, and ultimately better health outcomes for PLWH affected by substance use disorders.

Frequently Asked Questions (FAQs)

What is the name of this funding opportunity?

The opportunity is titled "The Integration of Infectious Diseases and Substance Abuse Intervention Services for Individuals Living with HIV (R01)" and is associated with FOA number RFA-DA-16-011.

What type of grant mechanism is used?

This is an NIH R01 research project grant opportunity.

Which federal agency sponsors this opportunity?

The sponsoring agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH).

Is this a discretionary grant program?

Yes. It is described as a discretionary NIH grant program.

What is the CFDA number for this program?

The program is listed under CFDA 93.279.

When was the FOA posted and when did it close?

The FOA was posted on December 7, 2015, and had a closing date of March 2, 2016.

What population is this FOA focused on?

The focus is on people living with HIV (PLWH) who also have substance use disorders and may have other co-occurring conditions.

What problem is the FOA trying to address?

The FOA targets gaps that occur when patients move between HIV clinics, addiction treatment programs, and other medical or behavioral health services. These gaps can lead to worse outcomes, and the goal is to reduce fragmentation across systems of care.

What is the main purpose of the funded research?

The purpose is to develop and evaluate organizational and systems-level interventions that make care more integrated, higher quality, sustainable over time, and cost-effective in real-world settings.

Does the FOA focus on individual-level clinical treatments?

Not primarily. The announcement emphasizes research that goes beyond testing individual-level treatments and instead focuses on organizational and systems-level changes that improve integration and implementation.

What kinds of research approaches are emphasized?

A major emphasis is on multidisciplinary research designed to improve how evidence-based practices are adopted and implemented across service systems.

What does the FOA seek to improve within HIV care settings?

It seeks projects that strengthen the routine use of evidence-based substance use screening and treatment within HIV centers and closely related medical settings.

What are examples of integration activities in HIV clinics that fit this FOA?

Examples described include integrating substance use identification and treatment into existing clinic workflows, staffing models, referral pathways, and clinical decision processes used by HIV clinics.

What does the FOA support within addiction treatment settings?

It supports projects that increase the uptake and integration of effective HIV care within addiction treatment settings, including interventions that improve linkage to HIV care, retention in HIV care, and adherence to antiretroviral therapy.

Why are retention in care and antiretroviral adherence highlighted?

The FOA notes that sustained engagement in care and adherence to antiretroviral therapy are critical to viral suppression and long-term health.

Does the FOA encourage addressing co-occurring conditions beyond HIV and substance use?

Yes. The FOA explicitly encourages integration efforts that address comorbid conditions commonly seen alongside HIV and substance use disorders.

What types of comorbid conditions are mentioned?

The information provided mentions co-infections and psychiatric disorders as examples of comorbid conditions applicants are encouraged to address.

What is the overarching care model goal described in the FOA?

The goal is to develop models of care that reflect the complexity of patients' lives and clinical needs, rather than treating HIV, addiction, and other conditions in isolation.

What are examples of systems-level strategies that may be relevant?

Examples mentioned include coordinated care pathways, shared care protocols, cross-training of staff, use of implementation supports, and system redesign approaches that reduce fragmentation across infectious disease services, addiction treatment, and behavioral health care.

What outcomes is this FOA ultimately trying to improve?

Intended outcomes include better engagement in care, improved adherence, improved management of co-occurring conditions, and better overall health outcomes for PLWH affected by substance use disorders.

Who is eligible to apply?

Eligibility is broad and includes: state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other entities as allowed under the additional eligibility language.

Are tribal governments and tribal organizations eligible?

Yes. Federally recognized Native American tribal governments and tribal organizations are listed as eligible applicants.

Are for-profit entities eligible?

Yes. For-profit organizations (other than small businesses) and small businesses are both listed as eligible.

Are higher education institutions eligible?

Yes. Public and state-controlled institutions of higher education and private institutions of higher education are both included in the eligibility list.

Are local governments eligible?

Yes. State, county, city or township governments and special district governments are included.

Are nonprofit organizations eligible if they do not have 501(c)(3) status?

Yes. Nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education) are included in the eligibility list.

What real-world setting focus is described?

The FOA emphasizes interventions that work in real-world settings where people actually receive care, with attention to sustainability and cost-effectiveness over time.

What is the core idea behind "integration" in this FOA?

Integration means HIV treatment and substance use services should not operate as parallel tracks. Instead, the FOA seeks coordinated, integrated service delivery that is easier for patients to navigate across HIV clinics, addiction treatment programs, and related medical and behavioral health services.

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