Opportunity Information: Apply for PA 08 007

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Integrative Prevention Research for Alcohol Users At Risk for HIV/AIDS (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Dec 5, 2008 and posted on Oct 17, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) State governments Native American tribal governments (Federally recognized) County governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:

The Integrative Prevention Research for Alcohol Users At Risk for HIV/AIDS (R21) funding opportunity (PA 08 007) is a National Institutes of Health grant announcement led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports exploratory and developmental projects that connect basic behavioral science with intervention research in order to prevent HIV/AIDS risk that is driven or worsened by alcohol use. The core idea is to move beyond treating alcohol use and HIV risk as separate issues and instead fund early-stage, innovative studies that explain how alcohol influences risky behavior and then translate those behavioral insights into practical prevention strategies.

This opportunity uses the NIH Exploratory/Developmental Research Project Grant mechanism (R21), which is designed for projects that are high-impact but still in a formative stage. The work encouraged under this FOA is meant to be integrative: applicants are expected to bridge foundational behavioral research (for example, mechanisms that link alcohol use to impaired judgment, sexual risk-taking, or reduced condom negotiation) with intervention development or testing (for example, brief interventions, risk-reduction counseling models, or other prevention approaches tailored to alcohol-using populations). The emphasis is specifically on preventing alcohol-related HIV/AIDS risk, meaning the proposed research should clearly articulate the role alcohol plays in increasing vulnerability to HIV and how the proposed intervention pathway addresses that relationship.

The FOA is categorized as a discretionary grant in the health area and is associated with CFDA number 93.273 (Alcohol Research Programs). The maximum award amount listed is an award ceiling of $200,000, and there is no cost sharing or matching requirement. The announcement notes multiple receipt dates rather than a single deadline, directing applicants to the full announcement for the specific submission cycles and due dates.

Eligibility is broad and intentionally inclusive. A wide range of domestic entities may apply, including public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and numerous government entities (state, county, city or township, special district governments, independent school districts, and Native American tribal governments and organizations). The announcement also states that foreign institutions are eligible to apply, eligible federal government agencies may apply, and faith-based or community-based organizations are allowed as applicants as well. In practice, this wide eligibility is meant to attract multidisciplinary teams and settings that can reach alcohol-using populations at risk for HIV, including community, clinical, and international contexts where alcohol-related HIV transmission risk is a significant concern.

Administratively, the opportunity was posted on October 17, 2007, with a creation date of December 5, 2008. It lists an archive date of October 8, 2010, indicating the original FOA is no longer active as a current announcement, but it remains relevant as a reference point for the type of research NIAAA sought to stimulate in this area. The full announcement and details were provided through the NIH grants guide at the linked page (http://grants.nih.gov/grants/guide/pa-files/PA-08-007.html). For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

Overall, this R21 FOA is best understood as a call for early-stage, integrative prevention science: studies that generate or refine behavioral knowledge about alcohol-related HIV risk and use that knowledge to shape and test intervention approaches that could later be expanded into larger efficacy or effectiveness trials.

FAQs: Integrative Prevention Research for Alcohol Users At Risk for HIV/AIDS (R21) (PA-08-007)

What is the title of this grant opportunity?

The opportunity is titled Integrative Prevention Research for Alcohol Users At Risk for HIV/AIDS (R21) and is identified as PA-08-007.

Which federal agency and NIH institute lead this opportunity?

This is a National Institutes of Health (NIH) grant announcement led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What is the main purpose of this funding opportunity?

The purpose is to support exploratory and developmental research that integrates basic behavioral science with intervention research to prevent HIV/AIDS risk that is driven or worsened by alcohol use.

What does "integrative prevention research" mean in this FOA?

In this FOA, "integrative" means the proposed project should connect foundational behavioral mechanisms (how alcohol influences decision-making and risk behavior) with prevention intervention development or testing (how those insights are turned into practical strategies to reduce HIV risk).

How is this different from treating alcohol use and HIV risk as separate topics?

The FOA emphasizes moving beyond separate tracks (one for alcohol, one for HIV risk). Instead, it calls for studies that explicitly explain alcohol's role in elevating HIV vulnerability and then use that explanation to shape prevention approaches aimed at alcohol-using populations at risk.

What grant mechanism does this opportunity use?

This opportunity uses the NIH Exploratory/Developmental Research Project Grant (R21) mechanism.

What kinds of projects are a fit for an R21 under this FOA?

The FOA is intended for projects that may be high-impact but are still formative or early-stage, including innovative studies that clarify mechanisms and then translate them into prevention strategies that could later be expanded into larger trials.

What research areas or examples does the FOA encourage?

The FOA encourages work that bridges behavioral mechanisms and interventions. Examples mentioned include studying mechanisms linking alcohol use to:

  • Impaired judgment
  • Sexual risk-taking
  • Reduced condom negotiation

And translating those insights into intervention approaches such as:

  • Brief interventions
  • Risk-reduction counseling models
  • Other prevention approaches tailored to alcohol-using populations

Is the focus on HIV/AIDS prevention or alcohol treatment?

The emphasis is specifically on preventing alcohol-related HIV/AIDS risk. The proposed research should clearly articulate how alcohol increases HIV vulnerability and how the proposed intervention pathway addresses that relationship.

What is the maximum award amount?

The listing provides an award ceiling of $200,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA 93.273, listed as Alcohol Research Programs.

What type of grant category is this?

The FOA is categorized as a discretionary grant in the health area.

Are there multiple deadlines or one due date?

The announcement notes multiple receipt dates rather than a single deadline and directs applicants to the full announcement for specific submission cycles and due dates.

Who is eligible to apply?

Eligibility is broad and includes many domestic entity types, including:

  • Public and private institutions of higher education
  • Nonprofits (with or without 501(c)(3) status)
  • For-profit organizations (including small businesses and other for-profits)
  • Government entities (state, county, city or township, special district, independent school districts)
  • Native American tribal governments and organizations

Are faith-based or community-based organizations allowed to apply?

Yes. The announcement states that faith-based and community-based organizations are allowed as applicants.

Are foreign institutions eligible?

Yes. The announcement states that foreign institutions are eligible to apply.

Can federal government agencies apply?

Yes. The announcement states that eligible federal government agencies may apply.

What kinds of teams or settings does the FOA aim to attract?

The FOA describes inclusive eligibility to attract multidisciplinary teams and a wide range of settings that can reach alcohol-using populations at risk for HIV, including community, clinical, and international contexts where alcohol-related HIV transmission risk is a significant concern.

When was this opportunity posted and what is the creation date listed?

The opportunity was posted on October 17, 2007, and it lists a creation date of December 5, 2008.

Is this FOA still active?

The listing includes an archive date of October 8, 2010, indicating the original FOA is no longer active as a current announcement, though it remains relevant as a reference for the kind of research NIAAA sought to stimulate.

Where can applicants find the full announcement?

The full announcement is available through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PA-08-007.html

Who is listed for help with access or technical issues?

For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

What is the overall "big picture" goal of projects supported by this FOA?

Overall, the FOA is a call for early-stage, integrative prevention science: generate or refine behavioral knowledge about alcohol-related HIV risk and use it to shape and test intervention approaches that could later be expanded into larger efficacy or effectiveness trials.

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Previous opportunity: Integrative Prevention Research for Alcohol Users At Risk for HIV/AIDS (RO1)

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