Opportunity Information: Apply for RFA HD 15 033

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Intellectual and Developmental Disabilities Research Centers 2015 (U54)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Feb 12, 2015 and posted on Feb 11, 2015.
  • Applicants must submit their applications by Apr 15, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,200,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $1,300,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Independent school districts Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments For profit organizations other than small businesses State governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Intellectual and Developmental Disabilities Research Centers 2015 (U54) funding opportunity (RFA-HD-15-033) is a National Institutes of Health (NIH) cooperative agreement program run under CFDA 93.865 (Child Health and Human Development Extramural Research) that supports the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). The overall goal is to strengthen and coordinate multidisciplinary research efforts that improve the diagnosis, prevention, treatment, and overall amelioration of intellectual and developmental disabilities (IDD). Rather than funding a stand-alone set of unrelated projects, the program is designed to build and maintain a research center environment that makes IDD research more integrated, more translational, and more efficient across departments and disciplines.

The FOA is structured around two main required components. First, applicants must propose core facilities ("Cores") that serve as shared resources for investigators. These cores are meant to enable interdisciplinary and translational IDD research by providing centralized expertise, services, infrastructure, and coordination that individual labs or single-project grants typically cannot provide as effectively on their own. A key point in the announcement is that the cores should not only support projects funded within the center, but also support IDD-related projects that already have funding from other sources. In practice, this means an IDDRC is expected to function as a hub: it enhances productivity and collaboration by making specialized tools, methods, and support available to a broad IDD research community at the applicant institution (and often partner institutions, depending on the center model and NIH expectations).

Second, each applicant must include at least one specific research project that aligns with one of five IDD focus themes identified by NIH as areas of research need. While the source text provided here does not list the five themes, the requirement signals that NIH wanted each center to demonstrate a clear scientific emphasis tied to priority needs in the IDD field, beyond simply offering general infrastructure. This also communicates that the center is expected to actively generate new knowledge and not only operate service cores.

A distinctive feature of the IDDRC model emphasized in the FOA is that most of the research projects that use the proposed core facilities are expected to be supported by independent funding streams, including federal, state, and private organizations. In other words, the U54 center award is primarily an enabling mechanism: it underwrites the shared core capacity and the collaborative framework that amplifies other funded research, while also supporting at least one center-associated research project tied to NIH priority themes. This approach is intended to maximize impact by leveraging a broader portfolio of grants and programs already active in the IDD space.

From an administrative and funding standpoint, this opportunity is categorized as a discretionary award using a cooperative agreement mechanism (U54). The cooperative agreement structure generally means NIH anticipates substantial scientific or programmatic involvement during the award period, compared with a standard grant, particularly in areas like coordination, performance expectations for cores, and alignment with program goals. The FOA anticipated making about 4 awards, with an estimated total funding level of $5.2 million and an award ceiling of $1.3 million per award. Cost sharing or matching was not required.

Eligibility was broad across public and private sectors, including state, county, and city governments; public and private institutions of higher education; nonprofits (including those with and without 501(c)(3) status, other than institutions of higher education); independent school districts; public housing authorities/Indian housing authorities; special district governments; small businesses; and for-profit organizations other than small businesses. The FOA also explicitly called out additional eligible applicant types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal government agencies. Foreign entities were not eligible, and foreign components of U.S. organizations were not allowed, consistent with NIH policy language noted in the announcement.

The opportunity was posted on February 11, 2015, created February 12, 2015, and closed on April 15, 2015, with an archive date of May 16, 2015. The full announcement was hosted on the NIH grants site (link provided in the notice), and NIH Office of Extramural Research (OER) webmaster contacts were listed for technical access and linking issues.

FAQs: Intellectual and Developmental Disabilities Research Centers 2015 (U54) - RFA-HD-15-033

What is this funding opportunity?

This opportunity is the Intellectual and Developmental Disabilities Research Centers 2015 (U54) program under NIH Funding Opportunity Announcement (FOA) RFA-HD-15-033. It supports the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs) and is administered as an NIH cooperative agreement.

Which NIH program classification and CFDA number apply?

The program is run under CFDA 93.865, titled Child Health and Human Development Extramural Research.

What is the main goal of the IDDRC program?

The overall goal is to strengthen and coordinate multidisciplinary research efforts that improve the diagnosis, prevention, treatment, and overall amelioration of intellectual and developmental disabilities (IDD).

Does this FOA fund a set of unrelated research projects?

No. The program is designed to build and maintain a research center environment rather than funding a stand-alone collection of unrelated projects. The emphasis is on integration, translation, coordination, and efficiency across departments and disciplines.

What are the required components of an application under this FOA?

The FOA is structured around two main required components: (1) core facilities ("Cores") that function as shared resources for investigators, and (2) at least one specific research project aligned with one of five NIH-identified IDD focus themes.

What are "Cores" in an IDDRC application?

Cores are shared resource components that provide centralized expertise, services, infrastructure, and coordination to enable interdisciplinary and translational IDD research. They are intended to offer capabilities that individual laboratories or single-project awards generally cannot provide as effectively on their own.

Who can use the proposed core facilities?

The cores are expected to support projects funded within the center and also support IDD-related projects that already have funding from other sources. The IDDRC is expected to serve as a hub that makes tools, methods, and specialized support broadly available to the IDD research community at the applicant institution (and often partner institutions, depending on the center model and NIH expectations).

Is a research project required, or can an applicant propose only cores?

At least one specific research project is required. The FOA indicates that each applicant must include a research project that aligns with one of five IDD focus themes identified by NIH.

Are the five IDD focus themes listed in the information provided here?

No. The information provided indicates that NIH identified five focus themes and required alignment with one of them, but the themes themselves are not listed in the source text summarized here.

What is distinctive about how research projects are supported in the IDDRC model?

A distinctive feature highlighted in the FOA is that most research projects using the proposed cores are expected to be supported by independent funding streams (including federal, state, and private organizations). In this model, the U54 award primarily enables shared core capacity and a collaborative framework while also supporting at least one center-associated research project aligned with NIH priorities.

What does "U54 cooperative agreement" mean in this context?

This opportunity uses a cooperative agreement mechanism (U54). The cooperative agreement structure indicates NIH anticipates substantial scientific or programmatic involvement during the award period compared with a standard grant, particularly around coordination, performance expectations for cores, and alignment with program goals.

How many awards were anticipated, and what was the expected funding level?

The FOA anticipated making about 4 awards, with an estimated total funding level of $5.2 million.

What was the maximum award amount (award ceiling)?

The award ceiling was $1.3 million per award.

Is cost sharing or matching required?

No. Cost sharing or matching was not required.

Who was eligible to apply?

Eligibility was broad across public and private sectors. Eligible applicants included state, county, and city governments; public and private institutions of higher education; nonprofits (with and without 501(c)(3) status, other than institutions of higher education); independent school districts; public housing authorities/Indian housing authorities; special district governments; small businesses; and for-profit organizations other than small businesses.

Were specific institution types explicitly mentioned as eligible?

Yes. The FOA explicitly called out additional eligible applicant types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal government agencies.

Are foreign organizations eligible to apply?

No. Foreign entities were not eligible.

Are foreign components of U.S. organizations allowed?

No. Foreign components of U.S. organizations were not allowed, consistent with NIH policy language referenced in the announcement.

When was the opportunity posted and when did it close?

The opportunity was posted on February 11, 2015, created on February 12, 2015, and closed on April 15, 2015.

What are the archive details for this FOA?

The archive date was May 16, 2015.

Where was the full announcement hosted?

The full announcement was hosted on the NIH grants website (a link was provided in the notice).

Who was listed for technical issues related to access or linking?

NIH Office of Extramural Research (OER) webmaster contacts were listed for technical access and linking issues.

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