Opportunity Information: Apply for RFA AI 15 056
Apply for RFA AI 15 056
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "International Centers of Excellence for Malaria Research (U19)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855, 93.856,.
- This funding opportunity was created on Oct 29, 2015 and posted on Oct 29, 2015.
- Applicants must submit their applications by Apr 15, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The International Centers of Excellence for Malaria Research (U19) funding opportunity (RFA AI 15 056) is a National Institutes of Health program designed to support large, multidisciplinary malaria research centers based in malaria-endemic regions. The main purpose is to strengthen malaria control and prevention by linking clinical research with field-based studies, so that discoveries and observations from patients, communities, vectors, and health systems inform each other in a coordinated way. In practical terms, the program is aimed at generating actionable evidence and tools that local and national decision-makers can use to improve malaria treatment, surveillance, and prevention strategies where malaria transmission is ongoing.
At the center of the announcement is the idea of creating or sustaining research hubs, described as International Centers of Excellence for Malaria Research (ICEMRs), that operate in-country or in-region rather than primarily within the United States. The FOA makes it clear that it is not meant to fund projects that could be conducted mainly at U.S.-based institutions. Instead, it emphasizes research anchored in malaria-endemic settings, where investigators can directly study transmission patterns, parasite and mosquito biology, drug and insecticide resistance, clinical outcomes, and the real-world performance of interventions. The expectation is that these centers will integrate multiple disciplines (for example, epidemiology, entomology, clinical medicine, immunology, genomics, pharmacology, and public health implementation) into a cohesive program that addresses local malaria challenges while also contributing broadly relevant knowledge.
The funding mechanism is a cooperative agreement (U19), which generally indicates substantial programmatic involvement by the funding agency compared with a standard research grant. Under a cooperative agreement, awardees typically work in closer partnership with NIH program staff on major scientific and operational aspects, such as coordination across sites, sharing data or resources, harmonizing methods, and ensuring the research aligns with overall program goals. This structure fits the ICEMR model because the centers are intended to function as part of a wider network of malaria research efforts, producing results that can be compared across different endemic settings and translated into evidence-based strategies.
The opportunity is categorized under Health and is associated with CFDA numbers 93.855 and 93.856. The agency listed is HHS-NIH11, reflecting NIH involvement (historically aligned with infectious disease priorities, including malaria). The FOA was posted and created on October 29, 2015, with an application closing date of April 15, 2016 (both original and current closing dates are the same in the provided record). The listed award ceiling is $1,000,000, meaning applications were expected to be scoped to that maximum funding level per award, though the total program size and the precise number of expected awards are not specified in the supplied data.
Eligibility is broad and includes many types of U.S. domestic entities and organizational structures: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The inclusion of “Others” with a note to see additional eligibility information suggests the FOA likely allowed certain additional applicant types or partnership configurations, which is common for international research programs where U.S. applicants often collaborate with in-country institutions and ministries. Even with broad eligibility, the program’s central requirement remains that the research be grounded in malaria-endemic settings and oriented toward outcomes relevant to malaria control and treatment.
Overall, this FOA supports the establishment of integrated malaria research centers that can produce locally relevant, policy-usable evidence through coordinated clinical and field investigations. Its emphasis is on generating knowledge and tools that government organizations and health care institutions can apply to reduce malaria burden, while ensuring the work is conducted where malaria occurs and where interventions must ultimately succeed.
Frequently Asked Questions (FAQs)
What is the funding opportunity called?
The opportunity is titled the International Centers of Excellence for Malaria Research (U19) funding opportunity, referenced as RFA AI 15 056.
Which agency is offering this grant?
The funding opportunity is offered through the National Institutes of Health (NIH) under HHS-NIH11.
What is the main purpose of this program?
The program is designed to support large, multidisciplinary malaria research centers based in malaria-endemic regions. Its purpose is to strengthen malaria control and prevention by linking clinical research with field-based studies, so that findings from patients, communities, vectors, and health systems inform each other in a coordinated way.
What does the program aim to produce for malaria control efforts?
The program is aimed at generating actionable evidence and tools that local and national decision-makers can use to improve malaria treatment, surveillance, and prevention strategies in settings where malaria transmission is ongoing.
What is an ICEMR in the context of this FOA?
An ICEMR is an International Center of Excellence for Malaria Research. In this FOA, ICEMRs are described as research hubs that operate in-country or in-region (in malaria-endemic settings), integrating multiple disciplines into a cohesive program focused on local malaria challenges while contributing broadly relevant knowledge.
Where is the research expected to take place?
The FOA emphasizes research anchored in malaria-endemic settings. It specifically states it is not meant to fund projects that could be conducted mainly at U.S.-based institutions.
Does the FOA allow projects primarily based at U.S. institutions?
No. The FOA makes clear it is not intended to fund projects that could be conducted mainly at U.S.-based institutions, and instead emphasizes in-country or in-region work in malaria-endemic areas.
What kinds of research are emphasized by this opportunity?
The FOA emphasizes integrated research that can directly study real-world malaria transmission and control issues, including transmission patterns, parasite biology, mosquito biology, drug resistance, insecticide resistance, clinical outcomes, and the performance of interventions in practice.
What is meant by linking clinical research with field-based studies?
It means coordinating patient- and clinic-based observations with community and field investigations (including vectors and health systems), so discoveries and observations from each level inform the others and produce coordinated evidence useful for malaria control and prevention.
What disciplines are expected to be integrated within an ICEMR?
The FOA expects multidisciplinary integration and gives examples such as epidemiology, entomology, clinical medicine, immunology, genomics, pharmacology, and public health implementation, organized into a cohesive center-level program.
What funding mechanism is used for this opportunity?
The mechanism is a cooperative agreement (U19), which indicates substantial programmatic involvement by the funding agency compared with a standard research grant.
What does a cooperative agreement (U19) imply for awardees?
Under a cooperative agreement, awardees typically work more closely with NIH program staff on major scientific and operational aspects such as coordination across sites, sharing data or resources, harmonizing methods, and ensuring alignment with overall program goals.
Is this program intended to operate as part of a network?
Yes. The FOA describes centers functioning as part of a wider network of malaria research efforts, producing results that can be compared across endemic settings and translated into evidence-based strategies.
What is the listed award ceiling?
The listed award ceiling is $1,000,000, meaning applications were expected to be scoped to a maximum funding level of up to that amount per award.
Does the provided information specify the number of awards?
No. The supplied information does not specify the total program size or the number of expected awards.
What is the opportunity category?
The opportunity is categorized under Health.
What CFDA numbers are associated with this FOA?
The FOA is associated with CFDA numbers 93.855 and 93.856.
When was the FOA posted and created?
The FOA was posted and created on October 29, 2015.
What is the application closing date?
The application closing date listed is April 15, 2016, and the record indicates both the original and current closing dates are the same.
Who is eligible to apply based on the information provided?
Eligibility is broad and includes many U.S. domestic entities and organizational structures, including state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses.
Are nonprofits without 501(c)(3) status eligible?
Yes. The eligibility list includes nonprofit organizations both with and without 501(c)(3) status.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed separately as eligible.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility list includes federally recognized Native American tribal governments and other tribal organizations.
Does the eligibility section suggest any additional eligible applicant types?
Yes. The inclusion of an “Others” category with a note to see additional eligibility information suggests the FOA may allow additional applicant types or partnership configurations, but the details are not provided in the supplied information.
What is the central program requirement even though eligibility is broad?
The central requirement described is that the research be grounded in malaria-endemic settings and oriented toward outcomes relevant to malaria control and treatment.
What types of outcomes does the FOA emphasize?
The FOA emphasizes outcomes that can inform or improve malaria treatment, surveillance, and prevention strategies, and that can be used by government organizations and health care institutions to reduce malaria burden.
What is the practical focus of the centers supported under this FOA?
In practical terms, the centers are intended to generate locally relevant, policy-usable evidence through coordinated clinical and field investigations carried out where malaria occurs and where interventions must succeed.
Browse more opportunities from the same category: Health
Next opportunity: Strengthening Epidemiology and Strategic Information in the Republic of Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR)
Previous opportunity: D.2 Leading Edge Aeronautics Research for NASA Project (LEARN3)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA AI 15 056
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA AI 15 056) also looked into and applied for these:
| Funding Opportunity |
|---|
| Strengthening Epidemiology and Strategic Information in the Republic of Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1675 Funding Number: CDC RFA GH16 1675 Agency: HHS-CDC-CGH Category: Health Funding Amount: $2,010,000 |
| NHLBI Progenitor Cell Translational Consortium Coordinating Center (U24) Apply for RFA HL 16 022 Funding Number: RFA HL 16 022 Agency: HHS-NIH11 Category: Health Funding Amount: Case Dependent |
| Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Foundational Functional Mapping of Neuroanatomy and Neurobiology of Organs (OT2) Apply for RFA RM 15 020 Funding Number: RFA RM 15 020 Agency: HHS-NIH11 Category: Health Funding Amount: $600,000 |
| Service Area Competition Apply for HRSA 16 008 Funding Number: HRSA 16 008 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| Protecting the Advances in Polio, Rubella and Measles Elimination: Strengthening Immunization Programs in the Americas. Apply for CDC RFA GH14 140103CONT16 Funding Number: CDC RFA GH14 140103CONT16 Agency: HHS-CDC Category: Health Funding Amount: Case Dependent |
| USAID Regional Health Integration to Enhance Services in East Central Uganda (USAID RHITES EC) Apply for RFA 617 16 000001 Funding Number: RFA 617 16 000001 Agency: USAID-UGA Category: Health Funding Amount: $57,000,000 |
| Technical Assistance in Support of HIV Prevention, Care, and Treatment Programs and Other Infectious Diseases that Impact HIV Infected Patients in Support of the President's Emergency Plan for AIDS Relief Apply for CDC RFA PS09 904SUPP Funding Number: CDC RFA PS09 904SUPP Agency: HHS-CDC Category: Health Funding Amount: Case Dependent |
| Rural Health Network Development Planning Program Apply for HRSA 16 017 Funding Number: HRSA 16 017 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| MCH Navigator Program Apply for HRSA 16 043 Funding Number: HRSA 16 043 Agency: HHS-HRSA Category: Health Funding Amount: Case Dependent |
| Supporting and Maintaining the Surveillance System for Chronic Kidney Disease in the United States Apply for CDC RFA DP16 1604 Funding Number: CDC RFA DP16 1604 Agency: HHS-CDC-NCCDPHP Category: Health Funding Amount: $700,000 |
| Local Non-governmental Partnerships for Sustained Country Leadership in Uganda under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH14 141202CONT16 Funding Number: CDC RFA GH14 141202CONT16 Agency: HHS-CDC Category: Health Funding Amount: Case Dependent |
| Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44) Apply for RFA EB 16 001 Funding Number: RFA EB 16 001 Agency: HHS-NIH11 Category: Health Funding Amount: Case Dependent |
| Integrated HIV Prevention Program for the Federal Police Force of Ethiopia Under the President's Emergency Plan for AIDS Relief Apply for CDC RFA PS10 10110SUPP Funding Number: CDC RFA PS10 10110SUPP Agency: HHS-CDC Category: Health Funding Amount: Case Dependent |
| COMPREHENSIVE PLATFORM FOR INTEGRATED COMMUNICATIONS INITIATIVE (CPICI) Apply for RFI 621 16 00002 Funding Number: RFI 621 16 00002 Agency: USAID-TAN Category: Health Funding Amount: $46,200,000 |
| NIDCD Early Career Research (ECR) Award (R21) Apply for PAR 16 057 Funding Number: PAR 16 057 Agency: HHS-NIH11 Category: Health Funding Amount: $100,000 |
| Tropical Medicine Research Centers (U19) Apply for RFA AI 16 002 Funding Number: RFA AI 16 002 Agency: HHS-NIH11 Category: Health Funding Amount: $500,000 |
| Improving the Quality of HIV Service Delivery and Other Priority Public Health Interventions through Training Support for Epidemiology, Monitoring and Evaluation (M&E), Survey and Laboratory Services in Nigeria under the President’s Emergency Plan Apply for CDC RFA GH16 1642 Funding Number: CDC RFA GH16 1642 Agency: HHS-CDC-CGH Category: Health Funding Amount: $5,000,000 |
| National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site (U24) Apply for PAR 16 047 Funding Number: PAR 16 047 Agency: HHS-NIH11 Category: Health Funding Amount: $1,000,000 |
| Implementation of One Health and Global Health Security Agenda in Viet Nam Apply for RFI 440 16 Funding Number: RFI 440 16 Agency: USAID-VIE Category: Health Funding Amount: $1,400,000 |
| Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Comprehensive Functional Mapping of Neuroanatomy and Neurobiology of Organs (OT2) Apply for RFA RM 15 018 Funding Number: RFA RM 15 018 Agency: HHS-NIH11 Category: Health Funding Amount: $2,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA AI 15 056", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.