Opportunity Information: Apply for 12 577

  • The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "International Collaborations in Organismal Biology Between US and Israeli Investigators" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.074 Biological Sciences.
  • This funding opportunity was created on Jan 3, 2013 and posted on Jun 29, 2012.
  • Applicants must submit their applications by Jan 11, 2013 Preliminary Proposal Due Date(s) (required) (due by 5 p.m. proposers local time) September 04, 2012 Full Proposal Deadline(s) December 03, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $230,000.00 in funding.
  • The number of recipients for this funding is limited to 40 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Organization Limit Proposals may only be submitted by the following Non profit, non academic organizations Independent museums, observatories, research labs, professional societies and similar organizations in the U.S. associated with educational or research activities. Universities and Colleges Universities and two and four year colleges (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Such organizations also are referred to as academic institutions.
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Opportunity Summary:

This grant opportunity, titled "International Collaborations in Organismal Biology Between US and Israeli Investigators" (NSF Publication 12-577), is a joint effort between the National Science Foundation (NSF) and the United States-Israel Binational Science Foundation (BSF). Its central purpose is to fund collaborative research projects that meaningfully pair US-based and Israeli investigators in biology areas covered by NSF's Division of Integrative Organismal Systems (IOS). The program is built around the idea that many of the most important biological questions now require coordinated international teams and integrated approaches that connect experiments with computation and theory.

Scientifically, the opportunity focuses on organismal biology through an integrative, systems-oriented lens. IOS emphasizes research that explains and predicts why organisms are built the way they are and why they function as they do, aiming for deeper understanding of the "emergent properties" of living systems. These emergent properties are features that arise from interactions among parts of an organism and cannot be fully understood by studying components in isolation. The announcement highlights several examples: complexity (how interacting components produce outcomes greater than the sum of parts), robustness (how organisms withstand stress or disturbance), communication (how parts of a system signal and influence one another), resilience (how organisms recover after perturbation), adaptability (how organisms change in response to challenges while maintaining overall function), and cooperation (coordinated behaviors that benefit more than a single component or individual). The program welcomes research across all organisms and explicitly encourages comparative work and the use of diverse model systems rather than restricting investigators to a narrow set of traditional models.

A strong theme is interdisciplinarity across levels of biological organization and across academic fields. Competitive projects are expected to connect multiple scales, for example linking molecular processes to physiology, neural function, development, behavior, or ecological interactions. The solicitation specifically encourages advanced computational methods, modeling, and theoretical frameworks alongside empirical experimentation. Teams that include expertise beyond core biology, such as behavioral science, physical sciences, mathematics, engineering, and computer science, are positioned to fit the program's intent, particularly when those collaborations produce integrative insights and testable predictions. Systems biology approaches are singled out as especially desirable when they genuinely combine experimentation, computation, and modeling to generate new conceptual or theoretical understanding that can be verified experimentally.

Within IOS, the solicitation calls out specific scientific emphasis areas where proposals may align: Behavioral Systems, Developmental Systems, Neural Systems, Physiological and Structural Systems, and Plant Genome Research. Because BSF supports a broad range of basic research, including the same general biology areas supported by IOS, applicants are encouraged to review both IOS and BSF program descriptions while shaping their project plans. A key requirement is that proposals include substantial collaboration between the US and Israeli partners, not just parallel work occurring in two places. The announcement pushes teams to design joint activities that are truly synergistic and provide clear added value beyond what each side could accomplish independently. Projects addressing organism-environment interactions and organismal adaptation are described as especially encouraged, signaling an interest in studies that connect organismal function to changing or variable environments.

From an administrative and funding standpoint, this is a discretionary grant opportunity in the science and technology research and development category. The estimated total funding is $2,500,000, with an award ceiling of $230,000 per award, and NSF anticipated about 40 awards. There is no cost-sharing or matching requirement. The CFDA listing is 47.074 (Biological Sciences). Eligibility includes US-based universities and colleges (including two- and four-year institutions and community colleges) that are accredited and have a US campus, submitting on behalf of their faculty. It also includes certain non-profit, non-academic US organizations tied to education or research activities, such as independent museums, observatories, research laboratories, and professional societies.

The timeline in the source data indicates the opportunity was posted June 29, 2012, with a required preliminary proposal due September 4, 2012 (by 5 p.m. local time), and a full proposal deadline of December 3, 2012, with a listed current closing date of January 11, 2013. The overall message is that this program is designed to catalyze high-impact, cross-border organismal biology research that integrates methods and disciplines, produces testable systems-level insight, and relies on genuine US-Israel collaboration as a core scientific strength rather than an add-on.

Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "International Collaborations in Organismal Biology Between US and Israeli Investigators" and is identified as NSF Publication 12-577.

Who is sponsoring or running this program?

It is a joint effort between the National Science Foundation (NSF) and the United States-Israel Binational Science Foundation (BSF).

What is the main purpose of the program?

The program is intended to fund collaborative research projects that meaningfully pair US-based and Israeli investigators in organismal biology areas covered by NSF's Division of Integrative Organismal Systems (IOS). The emphasis is on coordinated international teams and integrated approaches that connect experiments with computation and theory.

What scientific area does the program focus on?

The focus is organismal biology approached through an integrative, systems-oriented lens, aligned with NSF IOS interests. Projects are expected to help explain and predict why organisms are built the way they are and why they function as they do.

What does IOS mean by "emergent properties" in living systems?

Emergent properties are features that arise from interactions among parts of an organism and cannot be fully understood by studying components in isolation. Examples highlighted in the solicitation include complexity, robustness, communication, resilience, adaptability, and cooperation.

Are certain organisms or model systems required?

No. The program welcomes research across all organisms and explicitly encourages comparative work and the use of diverse model systems rather than restricting investigators to a narrow set of traditional models.

How important is interdisciplinarity for this solicitation?

Interdisciplinarity is a strong theme. Competitive projects are expected to connect multiple scales (for example, linking molecular processes to physiology, neural function, development, behavior, or ecological interactions) and may also integrate expertise beyond core biology (such as behavioral science, physical sciences, mathematics, engineering, and computer science) when that integration produces genuinely integrative insights and testable predictions.

Does the program encourage computational approaches and theory?

Yes. The solicitation specifically encourages advanced computational methods, modeling, and theoretical frameworks alongside empirical experimentation, especially when these approaches are combined to generate new conceptual or theoretical understanding that can be verified experimentally.

Are systems biology approaches relevant here?

Yes. Systems biology approaches are described as especially desirable when they genuinely combine experimentation, computation, and modeling to generate new understanding and testable, experimentally verifiable predictions.

What are the IOS emphasis areas mentioned in the opportunity?

The solicitation calls out the following IOS emphasis areas: Behavioral Systems, Developmental Systems, Neural Systems, Physiological and Structural Systems, and Plant Genome Research.

Should applicants consider BSF program descriptions too?

Yes. Because BSF supports a broad range of basic research, including the general biology areas supported by IOS, applicants are encouraged to review both IOS and BSF program descriptions when shaping their project plans.

What level of collaboration is required between the US and Israeli partners?

A key requirement is substantial collaboration between the US and Israeli partners. The program is not intended to fund two parallel projects running separately in two locations. Proposals are expected to include joint activities that are truly synergistic and provide clear added value beyond what each side could accomplish independently.

Are organism-environment interactions within scope?

Yes. Projects addressing organism-environment interactions and organismal adaptation are described as especially encouraged.

What type of funding opportunity is this?

It is a discretionary grant opportunity in the science and technology research and development category.

How much total funding is estimated for the program?

The estimated total funding is $2,500,000.

What is the maximum award amount (award ceiling)?

The award ceiling is $230,000 per award.

About how many awards did NSF anticipate?

NSF anticipated about 40 awards.

Is cost sharing or matching required?

No. There is no cost-sharing or matching requirement stated for this opportunity.

What is the CFDA number for this opportunity?

The CFDA listing is 47.074 (Biological Sciences).

Who is eligible to apply on the US side?

Eligibility includes US-based universities and colleges (including two- and four-year institutions and community colleges) that are accredited and have a US campus, submitting on behalf of their faculty. It also includes certain non-profit, non-academic US organizations tied to education or research activities, such as independent museums, observatories, research laboratories, and professional societies.

Is a preliminary proposal required?

Yes. The timeline indicates a required preliminary proposal deadline.

What were the key dates listed for this opportunity?

The opportunity was posted on June 29, 2012. The required preliminary proposal was due September 4, 2012 (by 5 p.m. local time). The full proposal deadline was December 3, 2012. The source data also lists a current closing date of January 11, 2013.

What is the program trying to catalyze overall?

The program is designed to catalyze high-impact, cross-border organismal biology research that integrates methods and disciplines, produces testable systems-level insight, and relies on genuine US-Israel collaboration as a core scientific strength rather than an add-on.

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