Opportunity Information: Apply for RFA TW 11 003

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "International Tobacco and Health Research and Capacity Building Program (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs 93.399 Cancer Control 93.989 International Research and Research Training.
  • This funding opportunity was created on Jul 12, 2011 and posted on Jul 12, 2011.
  • Applicants must submit their applications by Sep 15, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,300,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education County governments City or township governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public housing authorities/Indian housing authorities For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply.
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Opportunity Summary:

The International Tobacco and Health Research and Capacity Building Program (R01) is a National Institutes of Health (NIH) grant opportunity designed to reduce the health and economic harms caused by tobacco use in low and middle income countries (LMICs). The program focuses on two connected goals: supporting high-quality, locally relevant tobacco control research in LMIC settings and building sustainable research capacity within LMIC institutions and scientific teams. Projects are expected to address tobacco in all its forms, including smoked products and smokeless (non-combusted) tobacco, recognizing that patterns of use and related harms can vary widely across regions.

At the research level, the announcement encourages a wide range of studies that directly fit LMIC needs, including observational research to better understand patterns and determinants of tobacco use, intervention research to test prevention and cessation strategies, and policy research to evaluate or inform tobacco control laws and regulations. The FOA emphasizes transdisciplinary work, meaning proposals can and should draw from multiple fields where appropriate, such as epidemiology, behavioral science, health communication, implementation science, health services research, and public policy. The idea is to generate evidence that can realistically be used by local health systems and governments to curb tobacco-related illness and death.

A defining feature of this program is that capacity strengthening is not optional or secondary. Each application is expected to integrate a meaningful plan to develop LMIC-based capability to carry out and sustain tobacco control research over time. The level and type of training can vary depending on what the LMIC partner institution needs and what the collaborating investigators can support, but it should be substantial and clearly woven into the research plan. Capacity building may include developing skills in study design and methods, data systems and analysis, research ethics and regulatory oversight, intervention development, evaluation, dissemination, and translating findings into policy and practice.

The FOA is structured to promote genuine international collaboration, typically pairing investigators and institutions in the United States or other high income countries (HICs) with scientists and organizations in LMICs where tobacco use is already a major public health issue or is expected to become one. This partnership model is intended to be mutually beneficial: LMIC institutions gain stronger infrastructure and expertise to lead locally relevant research, while U.S./HIC investigators gain practical experience working in LMIC conditions and contribute to a broader global evidence base for tobacco control. Overall, the program aims to strengthen both the U.S. and international research communities, with an explicit emphasis on building long-term LMIC leadership and research independence.

Administratively, this opportunity was issued as RFA-TW-11-003 under the NIH and uses the R01 grant mechanism. It was categorized as discretionary grant funding and associated with multiple CFDA areas, including drug abuse and addiction research programs (93.279), cancer control (93.399), and international research and research training (93.989), reflecting tobacco's relevance to addiction, cancer, and global health capacity. The FOA listed an estimated total funding amount of $3.3 million and an award ceiling of $250,000. There was no cost-sharing or matching requirement. Key dates included a posted date of July 12, 2011, an original and current closing date of September 15, 2011, and an archive date of October 16, 2011.

Eligibility was broad and included many types of domestic U.S. applicants (such as public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, for-profit organizations other than small businesses, local and state governments, tribal governments and tribal organizations, and public housing authorities). The FOA also explicitly allowed applications from non-U.S. entities (foreign institutions) and non-U.S. components of U.S. organizations, and it highlighted inclusion of organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

In practical terms, a strong application under this FOA would propose a tobacco control research project that addresses a real LMIC tobacco burden problem, demonstrates an authentic partnership between HIC and LMIC investigators, and includes a clear, well-resourced capacity building plan that leaves the LMIC partner better equipped to conduct future tobacco research and translate findings into effective interventions and policy.

Frequently Asked Questions (FAQs)

What is the International Tobacco and Health Research and Capacity Building Program (R01)?

It is a National Institutes of Health (NIH) grant opportunity that supports tobacco control research and research capacity building focused on low and middle income countries (LMICs). The overall purpose is to reduce the health and economic harms caused by tobacco use in LMIC settings.

What are the main goals of this program?

The program has two connected goals: (1) support high-quality, locally relevant tobacco control research in LMIC settings, and (2) build sustainable research capacity within LMIC institutions and scientific teams so they can carry out and sustain tobacco control research over time.

What kinds of tobacco products are covered?

Projects are expected to address tobacco in all its forms, including smoked tobacco products and smokeless (non-combusted) tobacco. The opportunity notes that patterns of use and related harms can vary widely by region, so proposals should fit local realities.

What research topics and study types does the FOA encourage?

The announcement encourages a wide range of studies that directly fit LMIC needs, including observational research to understand patterns and determinants of tobacco use, intervention research to test prevention and cessation strategies, and policy research to evaluate or inform tobacco control laws and regulations.

Does the FOA require a specific scientific discipline or approach?

No. The FOA emphasizes transdisciplinary work, meaning proposals may draw from multiple fields as appropriate, such as epidemiology, behavioral science, health communication, implementation science, health services research, and public policy.

What does "transdisciplinary" mean in the context of this program?

It means the research can integrate methods and perspectives from more than one discipline to answer tobacco control questions that matter in LMIC settings. The intent is to produce evidence that can realistically be used by local health systems and governments.

Is capacity building optional, or is it required?

Capacity strengthening is not optional or secondary. Each application is expected to integrate a meaningful plan to develop LMIC-based capability to carry out and sustain tobacco control research over time, and that plan should be clearly woven into the research strategy.

What types of capacity building activities are envisioned?

The FOA indicates capacity building can include strengthening skills and infrastructure across areas such as study design and research methods, data systems and analysis, research ethics and regulatory oversight, intervention development, evaluation, dissemination, and translating findings into policy and practice.

How substantial does the training and capacity strengthening plan need to be?

The level and type of training may vary based on LMIC partner needs and what the collaborating investigators can support, but the FOA states it should be substantial, meaningful, and integrated into the overall project plan rather than treated as an add-on.

What is the expected partnership model for projects?

The FOA is structured to promote genuine international collaboration, typically pairing investigators and institutions in the United States or other high income countries (HICs) with scientists and organizations in LMICs where tobacco use is already a major public health issue or is expected to become one.

How is the collaboration intended to benefit both LMIC and HIC partners?

The partnership is intended to be mutually beneficial: LMIC institutions gain stronger infrastructure and expertise to lead locally relevant research, while U.S./HIC investigators gain practical experience working in LMIC conditions and contribute to a broader global evidence base for tobacco control.

What is the long-term intent of the program for LMIC institutions?

The program explicitly emphasizes building long-term LMIC leadership and research independence, leaving LMIC partners better equipped to conduct future tobacco research and translate findings into effective interventions and policy.

What is the FOA number for this opportunity?

This opportunity was issued as RFA-TW-11-003.

What grant mechanism does this FOA use?

The FOA uses the NIH R01 grant mechanism.

What type of funding is this considered?

It was categorized as discretionary grant funding.

Which CFDA areas are associated with this FOA?

The FOA is associated with multiple CFDA areas, including drug abuse and addiction research programs (93.279), cancer control (93.399), and international research and research training (93.989). This reflects tobacco's relevance to addiction, cancer, and global health capacity building.

How much funding was estimated to be available under this FOA?

The FOA listed an estimated total funding amount of $3.3 million.

What was the award ceiling?

The FOA listed an award ceiling of $250,000.

Is cost sharing or matching required?

No. The FOA stated there was no cost-sharing or matching requirement.

When was this opportunity posted?

The posted date was July 12, 2011.

What were the closing dates for this FOA?

The FOA listed an original closing date of September 15, 2011, and the current closing date was also September 15, 2011.

Is this funding opportunity still active?

No. The FOA included an archive date of October 16, 2011, indicating it has been archived.

Who was eligible to apply from the United States?

Eligibility was broad and included domestic U.S. applicants such as public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, for-profit organizations other than small businesses, local and state governments, tribal governments and tribal organizations, and public housing authorities.

Were non-U.S. (foreign) organizations eligible to apply?

Yes. The FOA explicitly allowed applications from non-U.S. entities (foreign institutions) as well as non-U.S. components of U.S. organizations.

Did the FOA encourage participation from specific institution types?

Yes. The FOA highlighted inclusion of organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

What would a strong application look like under this FOA?

Based on the FOA description, a strong application would propose a tobacco control research project that addresses a real LMIC tobacco burden problem, demonstrates an authentic partnership between HIC and LMIC investigators, and includes a clear, well-resourced capacity building plan that improves the LMIC partner's ability to conduct future tobacco research and translate findings into interventions and policy.

Does the FOA indicate how research should be used after it is completed?

Yes. The FOA emphasizes generating evidence that can realistically be used by local health systems and governments and highlights dissemination and translation of findings into policy and practice as part of capacity building activities.

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