Opportunity Information: Apply for RFA AA 12 009

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Interventions to Improve HIV/AIDS and Alcohol Related Outcomes (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Jan 26, 2012 and posted on Jan 26, 2012.
  • Applicants must submit their applications by Mar 26, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Independent school districts Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments State governments County governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Interventions to Improve HIV/AIDS and Alcohol Related Outcomes (U01) funding opportunity (RFA-AA-12-009) is a National Institutes of Health cooperative agreement program led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its main purpose is to support research teams in developing and strategically testing coordinated intervention approaches that reduce alcohol use and alcohol-related harms among people and communities affected by HIV. The central idea is that alcohol use can directly and indirectly worsen HIV outcomes, so the FOA encourages integrated, practical intervention strategies that can be deployed in real health care settings rather than isolated, one-off research projects.

A major emphasis of the announcement is not only on whether an intervention works, but on how it can be implemented and sustained within health systems. Applicants are expected to contribute to a newer, more durable framework for implementation research specifically tailored to HIV-positive individuals who use alcohol. In other words, the program is designed to move beyond efficacy questions and push toward systems-level improvements, including strategies that fit routine HIV care, can be maintained over time, and can measurably improve care delivery and patient outcomes. The long-term goal is to strengthen health care systems serving HIV-impacted populations by embedding effective alcohol-related interventions into standard practice in ways that are scalable and sustainable.

The FOA also signals that projects should, when possible, build from existing cohorts of HIV patients rather than starting from scratch. It highlights interest in including people at different stages of the HIV care continuum, including individuals who have been recently diagnosed and are just entering treatment as well as individuals who are already established in ongoing HIV care. This matters because intervention needs, engagement strategies, and health system touchpoints can differ substantially for someone just starting antiretroviral therapy compared with someone who has been in care for years, and the initiative appears to value intervention models that can address those differences while still being implementable in real-world settings.

From a funding and administrative standpoint, this is a discretionary grant opportunity using the cooperative agreement mechanism (U01). A cooperative agreement generally means NIH staff will have substantial involvement in the project beyond standard grant oversight, often to help coordinate across studies, align methods, support common outcomes, or facilitate multi-site collaboration. The total estimated funding listed for the FOA is $2,500,000, and there is no cost sharing or matching requirement. The opportunity was posted January 26, 2012, with an original and current closing date of March 26, 2012, and an archive date of April 26, 2012. The CFDA number associated with this program is 93.273 (Alcohol Research Programs).

Eligibility is broad across public and private sectors, reflecting the expectation that meaningful HIV and alcohol interventions may require partnerships among universities, health systems, community organizations, and other local or regional entities. Eligible applicants include federal recognized Native American tribal governments and tribal organizations, state and local governments (including county and city/township governments), public and state controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), public housing authorities/Indian housing authorities, independent school districts, special district governments, small businesses, and for-profit organizations other than small businesses. The FOA also explicitly lists additional eligible categories such as historically Black colleges and universities, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations are not eligible to apply, although foreign components as defined by NIH policy are allowed.

For applicants seeking the full announcement details, NIH provided an additional information link to the complete FOA text on the NIH grants site (http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-12-009.html). For technical access problems, NIH directed inquiries to the NIH Office of Extramural Research webmaster contacts listed in the announcement.

FAQs: Interventions to Improve HIV/AIDS and Alcohol Related Outcomes (U01) - RFA-AA-12-009

What is the name of this funding opportunity?

The funding opportunity is titled Interventions to Improve HIV/AIDS and Alcohol Related Outcomes (U01) and is identified as RFA-AA-12-009.

Which agency and institute are sponsoring this opportunity?

This is a National Institutes of Health (NIH) cooperative agreement program led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What is the main purpose of the program?

The main purpose is to support research teams in developing and strategically testing coordinated intervention approaches that reduce alcohol use and alcohol-related harms among people and communities affected by HIV.

What is the rationale for focusing on alcohol use in HIV-affected populations?

The FOA is built on the premise that alcohol use can directly and indirectly worsen HIV outcomes. The program encourages integrated intervention strategies intended to improve both alcohol-related and HIV-related outcomes.

What kinds of intervention approaches does the FOA encourage?

The FOA encourages integrated, practical intervention strategies that can be deployed in real health care settings, rather than isolated, one-off research projects.

Is this program only about whether an intervention works?

No. A major emphasis is on implementation and sustainability within health systems. The FOA highlights not only outcomes, but also how interventions can be implemented, maintained over time, and embedded into routine HIV care.

How does implementation research fit into this funding opportunity?

Applicants are expected to contribute to a more durable framework for implementation research tailored to HIV-positive individuals who use alcohol. The FOA is oriented toward systems-level improvements and real-world delivery of care.

What is the long-term goal described in the FOA?

The long-term goal is to strengthen health care systems serving HIV-impacted populations by embedding effective alcohol-related interventions into standard practice in ways that are scalable and sustainable.

Does the FOA prefer projects that use existing HIV patient cohorts?

Yes. The FOA indicates that projects should, when possible, build from existing cohorts of HIV patients rather than starting from scratch.

Which parts of the HIV care continuum are of interest?

The FOA highlights interest in including people at different stages of the HIV care continuum, including individuals who are recently diagnosed and entering treatment and individuals who are already established in ongoing HIV care.

Why does the FOA mention different stages of HIV care?

The FOA notes that intervention needs, engagement strategies, and health system touchpoints can differ for someone just starting antiretroviral therapy versus someone who has been in care for years. The initiative appears to value models that can address these differences while remaining implementable in real-world settings.

What funding mechanism is used for this opportunity?

This opportunity uses the U01 cooperative agreement mechanism.

What does a cooperative agreement (U01) imply for award management?

A cooperative agreement generally means NIH staff will have substantial involvement beyond standard grant oversight, often to help coordinate across studies, align methods, support common outcomes, or facilitate multi-site collaboration.

How much total funding is estimated for the FOA?

The FOA lists total estimated funding of $2,500,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

What are the key dates for this opportunity?

The opportunity was posted January 26, 2012. The original and current closing date is March 26, 2012. The archive date is April 26, 2012.

What is the CFDA number for this program?

The CFDA number associated with this program is 93.273 (Alcohol Research Programs).

Who is eligible to apply?

Eligibility is broad across public and private sectors. Eligible applicants include:

  • Federal recognized Native American tribal governments and tribal organizations
  • State and local governments (including county and city/township governments)
  • Public and state controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits)
  • Public housing authorities/Indian housing authorities
  • Independent school districts
  • Special district governments
  • Small businesses
  • For-profit organizations other than small businesses
  • Historically Black colleges and universities (HBCUs)
  • Hispanic-serving institutions (HSIs)
  • Tribally controlled colleges and universities
  • Alaska Native and Native Hawaiian serving institutions
  • Faith-based and community-based organizations
  • Regional organizations
  • U.S. territories or possessions
  • Eligible federal agencies

Are non-U.S. (foreign) institutions eligible to apply?

No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations are not eligible to apply.

Are foreign components allowed in any form?

Yes. While non-U.S. institutions and non-U.S. components of U.S. organizations are not eligible to apply, the FOA states that foreign components (as defined by NIH policy) are allowed.

Where can applicants find the complete FOA text?

The complete FOA text is available on the NIH grants site at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-12-009.html

Who should be contacted for technical access problems related to the FOA?

For technical access problems, NIH directed inquiries to the NIH Office of Extramural Research webmaster contacts listed in the announcement.

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