Isotope Production | Apply Online

Opportunity Summary:

The Department of Energy (DOE), through the Office of Science (SC) and its Office of Nuclear Physics (NP), issued this grant opportunity to strengthen domestic production of both stable and radioactive isotopes. The central purpose is practical and research-driven: improve the availability of isotopes that are essential inputs for a broad range of scientific and national needs. The announcement emphasizes that isotope supply underpins work in medicine (including diagnostic and therapeutic applications), nuclear and particle physics, biology and biochemistry, chemistry, agriculture, ecology and environmental tracing, materials science, and national security-related research. In other words, DOE is looking to support projects that can produce isotopes that researchers actually need and may not be able to obtain reliably through existing sources.

This Funding Opportunity Announcement (FOA) is titled "Isotope Production" (DE-FOA-0000517) and sits under the Office of Science Financial Assistance Program (CFDA 81.049). The activity category is science and technology and other R&D, and the funding instrument is a grant. DOE’s stated goal is to enhance isotope availability for research applications, so competitive applications would typically be expected to show a clear pathway to producing stable and/or radioactive isotopes in the United States, along with a credible plan for meeting research community demand.

DOE notes that, when deciding what to prioritize for awards, the Office of Nuclear Physics considers guidance from the Nuclear Science Advisory Committee on Isotopes (NSAC I). The FOA points applicants to two key NSAC isotopes reports from 2009: "Compelling Research Opportunities using Isotopes" and "Isotopes for the Nation’s Future: A Long Range Plan." The inclusion of these reports signals that proposals aligned with the needs and recommendations identified by NSAC (for example, improving access to hard-to-get isotopes or addressing known supply gaps) are likely to fit well with the program’s intent.

The FOA anticipated about five awards, with an estimated total program funding of $1,000,000. Individual awards were expected to fall between $200,000 (floor) and $330,000 (ceiling). The opportunity did not require cost sharing or matching, which generally lowers barriers for applicants by allowing the federal funds to cover the proposed work without a required non-federal contribution.

Eligibility was broadly described as unrestricted for domestic applicants, meaning many types of U.S.-based organizations could apply as the lead institution. However, there are specific exclusions: other federal agencies are not eligible as leads, Federally Funded Research and Development Center (FFRDC) contractors are excluded, and certain nonprofit organizations classified under IRS section 501(c)(4) that engaged in lobbying activities after December 31, 1995 are also excluded. Outside of those categories, the competition was open to domestic entities, subject to any additional clarifications in the full announcement text.

In terms of timing, the opportunity was posted on May 13, 2011. While the original closing date was listed as August 5, 2011, the current closing date was extended to September 26, 2011, and the archive date is November 4, 2011. The FOA also mentions a companion program announcement for DOE laboratories (LAB 11-517) to be posted through the Office of Science grants and contracts website, indicating that DOE was coordinating isotope production support across both external applicants and the national lab system.

Administrative handling is associated with the DOE Chicago Service Center. For applicants needing help accessing the full announcement or having programmatic questions, the FOA lists contacts including a grants analyst, Kerwin A. Lawrence (kerwin.lawrence@science.doe.gov, 301-903-9842), and a program manager, Marc A. Garland (Marc.Garland@science.doe.gov, 301-903-9576). An additional information link is provided via FedConnect, which is where applicants typically find full solicitation details, amendments, and submission instructions.

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