Opportunity Information: Apply for PA 08 114
Apply for PA 08 114
- The National Institutes of Health in the education food and nutrition health sector is offering a public funding opportunity titled "Lab to Marketplace Tools for Biomedical and Behavioral Research (SBIR R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.273 Alcohol Research Programs 93.361 Nursing Research 93.389 National Center for Research Resources 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jan 26, 2009 and posted on Apr 9, 2008.
- Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
Lab to Marketplace Tools for Biomedical and Behavioral Research (SBIR R43/R44), Funding Opportunity Number PA 08 114, is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant opportunity designed to push promising research tools out of the lab and into real-world commercial distribution. The core idea is to take technologies that were originally created in academic labs or other non-small-business settings and support their transition into products that can be broadly used by the biomedical and behavioral research communities. Rather than funding basic discovery science, the emphasis is on practical translation: turning a prototype or early-stage tool into something robust, reliable, easier to use, and ready for wider adoption.
A major theme of the announcement is collaboration. NIH expects that many of these lab-originated technologies will need close involvement from the original inventors or developer teams to successfully mature into products. Small Business Concerns (SBCs) are the eligible applicants and are encouraged to partner with those original developers in a structured way. The FOA explicitly notes that this can be done through a variety of arrangements, including multi-Principal Investigator (multi-PI) projects, reflecting NIHs expectation that both technical continuity (from the inventors) and commercialization-oriented development (from the small business) are often needed to move a tool to market.
The FOA uses the SBIR R43/R44 mechanisms, meaning it supports Phase I, Phase II, and Fast Track submissions. Phase I generally supports early feasibility and proof-of-concept work, while Phase II supports more substantial development, optimization, validation, and steps needed for commercialization. Fast Track allows applicants to propose a combined Phase I and Phase II plan in a single application, which can speed the path for projects that can lay out a credible, staged development and commercialization strategy from the start. The announcement also notes that it runs in parallel with a related NIH Blueprint for Neuroscience Research opportunity (PA 08 071) focused specifically on tools for brain and behavioral research, signaling that PA 08 114 is broader across biomedical and behavioral research domains rather than confined to neuroscience.
In terms of funding levels, the FOA allows relatively sizable SBIR budgets to support tool hardening and productization. For Phase I, applicants may request up to 350,000 dollars in total costs per year for up to two years. For Phase II, applicants may request up to 600,000 dollars in total costs per year for up to three years. For Phase II competing renewals, budgets must follow any participating NIH Institute and Center specific limits described in the SBIR Omnibus Solicitation Program Descriptions and Research Topics, which means applicants need to cross-check institute-specific guidance when planning later-stage requests. As with typical federal grant language, awards depend on available appropriations and whether NIH receives enough high-quality, meritorious applications to justify funding.
Administratively, this is a discretionary grant program with no cost sharing or matching requirement, and eligibility is limited to small businesses. The opportunity was posted April 9, 2008, with a closing date of May 7, 2011, and an archive date of June 7, 2011, indicating it is no longer open but remains useful as a reference point for similar NIH SBIR translation-focused solicitations. The FOA is tied to multiple CFDA numbers spanning a range of NIH research areas (for example, human genome research, deafness and communication disorders, complementary and integrative health, alcohol research, nursing research, research resources, arthritis and musculoskeletal and skin diseases, and broader biomedical research and training), reinforcing that the intended tools can cut across many biomedical and behavioral research fields as long as they are positioned for commercialization and broad research use.
Overall, PA 08 114 is best understood as a bridge between academic invention and market-ready research products. It invites small businesses to take lab-built technologies and do the unglamorous but essential work of engineering, usability improvements, validation, documentation, packaging, and other development steps that make a tool dependable and adoptable by the wider research community, while leveraging close cooperation with the original technology creators to preserve scientific integrity and accelerate successful commercialization.
Frequently Asked Questions (FAQs)
What is the "Lab to Marketplace Tools for Biomedical and Behavioral Research (SBIR R43/R44)" opportunity?
It is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) funding opportunity intended to move promising biomedical and behavioral research tools from their original lab settings into real-world commercial distribution. The focus is on taking tools created in academic labs or other non-small-business environments and supporting their transition into broadly usable products for the research community.
What is the Funding Opportunity Number (FOA number)?
The FOA number is PA 08 114.
Which agency offers this grant opportunity?
This opportunity is offered by the National Institutes of Health (NIH).
What is the main goal of PA 08 114?
The main goal is practical translation rather than basic discovery. The program emphasizes turning a prototype or early-stage research tool into something robust, reliable, easier to use, and ready for wider adoption and commercialization.
Is this opportunity intended to fund basic research or product development?
Based on the description provided, the emphasis is on product-oriented translation and commercialization steps (for example, hardening and productization), not basic discovery science.
What kinds of technologies are targeted by this FOA?
The FOA targets research tools that originated in academic labs or other non-small-business settings and need further development to become market-ready products that can be broadly used by biomedical and behavioral research communities.
Who is eligible to apply?
Eligibility is limited to Small Business Concerns (SBCs).
Does the FOA encourage collaboration with the original inventors or developers?
Yes. A major theme is collaboration, and NIH expects many lab-originated technologies will need close involvement from the original inventors or developer teams to successfully mature into products.
How can a small business structure collaboration with the original developers?
The FOA notes that collaboration can be structured through a variety of arrangements, including multi-Principal Investigator (multi-PI) projects, to combine technical continuity from inventors with commercialization-oriented development from the small business.
What SBIR mechanisms does this FOA use?
This FOA uses the SBIR R43/R44 mechanisms.
Does the FOA support Phase I, Phase II, and Fast Track?
Yes. It supports Phase I, Phase II, and Fast Track submissions.
What is the general purpose of Phase I under this FOA?
Phase I generally supports early feasibility and proof-of-concept work.
What is the general purpose of Phase II under this FOA?
Phase II supports more substantial development, optimization, validation, and steps needed for commercialization.
What is Fast Track in the context of this FOA?
Fast Track allows applicants to propose a combined Phase I and Phase II plan in a single application. It can speed the path for projects that can present a credible staged development and commercialization strategy from the start.
How much funding can be requested for Phase I?
Phase I applicants may request up to $350,000 in total costs per year for up to two years.
How much funding can be requested for Phase II?
Phase II applicants may request up to $600,000 in total costs per year for up to three years.
Are there special budget rules for Phase II competing renewals?
Yes. For Phase II competing renewals, budgets must follow any participating NIH Institute and Center-specific limits described in the SBIR Omnibus Solicitation Program Descriptions and Research Topics. Applicants need to cross-check institute-specific guidance when planning later-stage requests.
Is cost sharing or matching required?
No. The program is described as having no cost sharing or matching requirement.
Is this a discretionary grant program?
Yes. It is described as a discretionary grant program.
Does the FOA focus on a specific research area like neuroscience only?
No. The description indicates PA 08 114 is broader across biomedical and behavioral research domains. It also notes a related NIH Blueprint for Neuroscience Research opportunity (PA 08 071) that is focused specifically on tools for brain and behavioral research, implying PA 08 114 is not confined to neuroscience.
What is the relationship between PA 08 114 and PA 08 071?
The FOA runs in parallel with PA 08 071, a related NIH Blueprint for Neuroscience Research opportunity focused on tools for brain and behavioral research. PA 08 114 is positioned as broader across biomedical and behavioral research domains.
When was this opportunity posted, and is it still open?
It was posted on April 9, 2008. The closing date was May 7, 2011, and the archive date was June 7, 2011, indicating it is no longer open.
What does it mean that the FOA is archived?
Based on the dates provided (archive date June 7, 2011), it indicates the opportunity is no longer active for new submissions, but it may still serve as a reference for similar NIH SBIR solicitations focused on translation of research tools.
What kinds of activities does the FOA emphasize for moving tools to market?
It emphasizes the practical work needed to make a tool dependable and adoptable, including engineering, usability improvements, validation, documentation, packaging, and other development steps that support commercialization and broad research use.
How does NIH describe the overall purpose of PA 08 114 in plain terms?
It is described as a bridge between academic invention and market-ready research products, supporting the transition of lab-built technologies into commercially distributed tools used widely by the biomedical and behavioral research communities.
Do awards depend on anything beyond application quality?
Yes. As described, awards depend on available appropriations and whether NIH receives enough high-quality, meritorious applications to justify funding.
What do the CFDA numbers indicate about the scope of this FOA?
The FOA is tied to multiple CFDA numbers spanning a range of NIH research areas (examples provided include human genome research, deafness and communication disorders, complementary and integrative health, alcohol research, nursing research, research resources, arthritis and musculoskeletal and skin diseases, and broader biomedical research and training). This reinforces that tools can cut across many biomedical and behavioral research fields, as long as they are positioned for commercialization and broad research use.
Browse more opportunities from the same category: Education Food and Nutrition Health
Next opportunity: Small Business Innovation Research Competing Renewal Awards for Biomedical and Behavior Research Tools (SBIR R44)
Previous opportunity: New Technologies for Transient Molecular Complex Characterization (STTR R41/R42)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 08 114) also looked into and applied for these:
| Funding Opportunity |
|---|
| Exploratory/Developmental Clinical Research Grants in Obesity (R21) Apply for PA 09 124 Funding Number: PA 09 124 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $200,000 |
| Biobehavioral Methods to Improve Outcomes Research (R01) Apply for PA 09 125 Funding Number: PA 09 125 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition (R21) Apply for PA 09 151 Funding Number: PA 09 151 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $200,000 |
| Development and Validation of Disease Biomarkers (R01) Apply for PA 09 204 Funding Number: PA 09 204 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Health Disparities in NIDDK Diseases (R01) Apply for PA 09 262 Funding Number: PA 09 262 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Development of Assays for High Throughput screening for use in Probe and Pre therapeutic Discovery (R01) Apply for PA 10 213 Funding Number: PA 10 213 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Health Promotion Among Racial and Ethnic Minority Males (R01) Apply for PA 10 236 Funding Number: PA 10 236 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Lab to Marketplace Tools for Brain and Behavioral Research (SBIR R43/R44) Apply for PA 11 134 Funding Number: PA 11 134 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
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