Opportunity Information: Apply for PA 12 241

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Large Research Projects for Prevention and Management of Healthcare Associated Infections (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Jul 19, 2012 and posted on Jul 19, 2012.
  • Applicants must submit their applications by Nov 5, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments State governments Private institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Faith based or Community based Organizations Indian/Native American Tribal Governments (Other than Federally Recognized).
Apply for PA 12 241

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Opportunity Summary:

The Agency for Healthcare Research and Quality (AHRQ) offered this discretionary grant opportunity, titled "Large Research Projects for Prevention and Management of Healthcare Associated Infections (R01)," under Funding Opportunity Number PA 12 241. The program is focused on healthcare-associated infections (HAIs) and supports large, research-intensive projects intended to strengthen what is known about how HAIs are detected, prevented, reduced, and managed in real-world healthcare settings. In practical terms, the opportunity is aimed at generating evidence that can improve patient safety and the quality of care by reducing infections that patients acquire while receiving medical treatment, and by improving how healthcare systems respond when infections occur.

The stated purpose of the funding announcement is to solicit Research Project Grant (R01) applications that advance the knowledge base around HAIs. While the announcement does not limit applicants to a single narrow topic area, it emphasizes broad research areas tied to the detection and measurement of HAIs, prevention strategies and interventions, reduction approaches that lower infection burden, and management practices that improve outcomes and limit spread. The overall intent is to fund substantial, rigorous research that can inform practice, policy, and operational decision-making in healthcare organizations, rather than small pilot efforts.

The mechanism of support for this opportunity is the AHRQ R01 award mechanism, which is commonly used for investigator-driven research projects with clearly defined aims and a multi-year plan of work. Because it is positioned as a "Large Research Projects" program, the expectation is that proposed studies may involve more complex designs, larger samples, multiple sites, implementation or evaluation components, advanced analytic methods, or other elements that require a larger scale than smaller grant mechanisms. The funding announcement also signals that AHRQ is open to a range of research approaches as long as they are well-justified and likely to produce actionable findings related to HAIs.

In terms of funding levels and the number of awards, the announcement does not set a fixed dollar amount per award or a guaranteed number of grants. Instead, it notes that award size and project duration are expected to vary depending on the nature and scope of each application. The total amount awarded and how many projects ultimately receive funding depend on the number of applications submitted, the scientific and practical merit of those applications, their proposed duration, and their requested budgets. Like many federal research announcements, awards are contingent on the availability of appropriated funds and on receiving a sufficient pool of high-quality, fundable proposals.

Eligibility is broad and includes multiple types of public and private organizations. Eligible applicants include state governments, county governments, city or township governments, public and state-controlled institutions of higher education, and private institutions of higher education. Tribal entities are also included, both federally recognized Native American tribal governments and other Native American tribal organizations that are not federally recognized. The announcement also indicates additional eligible applicants such as eligible agencies of the federal government as well as faith-based and community-based organizations, reflecting an interest in enabling partnerships that can connect research to real clinical and community contexts where HAI prevention and management efforts take place.

The opportunity falls under the Health funding activity category and is associated with CFDA number 93.226, labeled "Research on Healthcare Costs, Quality and Outcomes," which aligns with AHRQ's mission to improve the safety, quality, effectiveness, and efficiency of healthcare delivery. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of the award. The funding announcement was posted and created on July 19, 2012, with an original and current closing date of November 5, 2015, and an archive date of December 6, 2015, indicating the opportunity is no longer open but remains available as a historical reference.

For applicants or interested parties seeking the full text of the announcement, the additional information link directs readers to the NIH Grants Guide posting for PA 12 241. The contact information provided is for technical access and linking support through the NIH Office of Extramural Research (OER) webmaster email, which is typical for announcements hosted in the NIH/AHRQ grants infrastructure.

Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "Large Research Projects for Prevention and Management of Healthcare Associated Infections (R01)."

Which agency is offering this opportunity?

This discretionary grant opportunity is offered by the Agency for Healthcare Research and Quality (AHRQ).

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is PA 12 241.

What is the primary focus of the program?

The program focuses on healthcare-associated infections (HAIs) and supports large, research-intensive projects to strengthen knowledge about how HAIs are detected, prevented, reduced, and managed in real-world healthcare settings.

What problem is this grant trying to address?

The opportunity is aimed at generating evidence that can improve patient safety and the quality of care by reducing infections that patients acquire while receiving medical treatment and improving how healthcare systems respond when infections occur.

What type of applications is AHRQ soliciting under this announcement?

AHRQ is soliciting Research Project Grant (R01) applications that advance the knowledge base around healthcare-associated infections (HAIs).

What research areas are emphasized in the announcement?

The announcement emphasizes broad research areas tied to (1) detection and measurement of HAIs, (2) prevention strategies and interventions, (3) reduction approaches that lower infection burden, and (4) management practices that improve outcomes and limit spread.

Does the announcement restrict applicants to one narrow topic?

No. It does not limit applicants to a single narrow topic area, but it does emphasize research connected to detection/measurement, prevention, reduction, and management of HAIs.

What is the funding mechanism for this opportunity?

The mechanism of support is the AHRQ R01 award mechanism.

What does "Large Research Projects" imply for proposed studies?

It signals an expectation of substantial, rigorous projects that may involve complex study designs, larger samples, multiple sites, implementation or evaluation components, advanced analytic methods, or other elements that require a larger scale than smaller grant mechanisms.

Is AHRQ open to different research approaches?

Yes. The announcement indicates AHRQ is open to a range of research approaches, as long as the methods are well-justified and likely to produce actionable findings related to HAIs.

Are small pilot projects the main intent of this funding opportunity?

No. The overall intent is to fund substantial, rigorous research that can inform practice, policy, and operational decision-making in healthcare organizations, rather than small pilot efforts.

How much funding is available per award?

The announcement does not set a fixed dollar amount per award. Award size is expected to vary depending on the nature and scope of each application.

How long can projects last?

Project duration is expected to vary depending on the nature and scope of the proposed work, as described in each application.

How many awards will be made?

The announcement does not guarantee a specific number of awards. The number of funded projects depends on factors such as the number of applications submitted, the merit of applications, proposed duration, requested budgets, and availability of appropriated funds.

What factors influence whether an award is made?

Awards are contingent on the availability of appropriated funds and on receiving a sufficient pool of high-quality, fundable proposals. The total amount awarded and the number of awards also depend on application merit, proposed duration, and requested budgets.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement for this opportunity.

Who is eligible to apply?

Eligibility is broad and includes public and private organizations, including state governments, county governments, city or township governments, public and state-controlled institutions of higher education, and private institutions of higher education.

Are tribal entities eligible?

Yes. Eligible applicants include federally recognized Native American tribal governments and other Native American tribal organizations that are not federally recognized.

Are federal agencies eligible to apply?

Yes. The announcement lists eligible agencies of the federal government among eligible applicants.

Are faith-based or community-based organizations eligible?

Yes. Faith-based and community-based organizations are included as eligible applicants, reflecting interest in partnerships that connect research to real clinical and community contexts.

What funding activity category is this opportunity associated with?

The opportunity falls under the Health funding activity category.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA number 93.226, labeled "Research on Healthcare Costs, Quality and Outcomes."

How does this CFDA align with AHRQ's mission?

It aligns with AHRQ's mission to improve the safety, quality, effectiveness, and efficiency of healthcare delivery, consistent with research on costs, quality, and outcomes.

When was the funding announcement posted?

The funding announcement was posted and created on July 19, 2012.

What was the closing date for applications?

The original and current closing date listed is November 5, 2015.

Is this opportunity still open?

No. The archive date is December 6, 2015, indicating the opportunity is no longer open and is available as a historical reference.

Where can someone find the full text of the announcement?

The additional information link directs readers to the NIH Grants Guide posting for PA 12 241.

Who is the listed contact for help?

The contact information provided is for technical access and linking support through the NIH Office of Extramural Research (OER) webmaster email.

What kind of help does the listed contact provide?

The listed contact is described as support for technical access and linking related to the announcement, which is typical for postings hosted in the NIH/AHRQ grants infrastructure.

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