Opportunity Information: Apply for PAR 15 189

  • The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Lasker Clinical Research Scholars Program (Si2/R00)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.140 Intramural Research Training Award 93.172 Human Genome Research 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.398 Cancer Research Manpower 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.867 Vision Research.
  • This funding opportunity was created on Apr 28, 2015 and posted on Apr 28, 2015.
  • Applicants must submit their applications by Aug 27, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Special district governments For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education State governments County governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Lasker Clinical Research Scholars Program (Si2/R00), funding opportunity number PAR-15-189, is a National Institutes of Health (NIH) discretionary grant designed to help launch the careers of early-stage, independent clinical researchers. The core purpose of the program is to provide strong support for research activities at a formative point when clinician-scientists are building momentum as independent investigators. In practice, this kind of program is meant to bridge the gap between mentored training and full independence by giving promising clinical researchers the resources and structure to establish a focused research direction, generate publishable results, and compete successfully for longer-term research support.

This opportunity uses the NIH grant funding instrument and is tied to an activity category spanning education and health-related research areas, reflecting its emphasis on developing the clinical research workforce while enabling high-impact biomedical studies. The announcement lists an expected total of about five awards, indicating a competitive program with a limited number of funded slots. The program aligns with a broad range of NIH mission areas, as reflected by the multiple CFDA numbers included in the source information. These CFDA listings cover major research domains such as environmental health, genomics, sleep disorders, mental health, nursing research, and many disease-focused areas including cancer, cardiovascular disease, lung and blood diseases, arthritis and musculoskeletal conditions, diabetes and kidney disease, neurological disorders, allergy and infectious diseases, child health and human development, and vision research. The breadth of these CFDA numbers signals that the program is not limited to a single institute or disease area; instead, it is positioned to support clinical research across many NIH-relevant topics, provided the project fits NIH priorities and the applicant meets the program’s intent of supporting early independent clinical investigators.

Eligibility is broad and includes many types of U.S.-based organizations that commonly apply for federal research funding. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses and other for-profit entities), and multiple levels of government (city/township, county, state, special districts, and independent school districts). The opportunity also explicitly includes certain mission-driven and community-oriented institution types and designations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations. At the same time, the announcement makes clear that non-U.S. entities are not eligible to apply, and foreign components are not allowed under NIH policy for this program. That means foreign institutions, non-domestic components of U.S. organizations, and other foreign components as defined by the NIH Grants Policy Statement cannot be part of the application structure.

The posting and timing details show that the FOA was posted and created on April 28, 2015, with an original and current closing date of August 27, 2015, and an archive date of September 27, 2015. There is no cost-sharing or matching requirement, which is important for applicants because it indicates the award does not require the institution to commit non-federal matching funds as a condition of funding, beyond any standard NIH expectations around allowable costs and institutional support.

For official details, NIH provided an additional information link to the full announcement on the NIH grants site (http://grants.nih.gov/grants/guide/pa-files/PAR-15-189.html). Applicants or prospective applicants who encounter technical problems accessing the announcement are directed to contact the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is the listed point of contact for access and linking issues.

Frequently Asked Questions (FAQs)

What is the Lasker Clinical Research Scholars Program (Si2/R00)?

The Lasker Clinical Research Scholars Program (Si2/R00) is an NIH discretionary grant opportunity designed to help launch the careers of early-stage, independent clinical researchers by providing strong support for research activities at a key formative stage.

What is the funding opportunity number for this program?

The funding opportunity number is PAR-15-189.

What is the main purpose of this program?

The core purpose is to support clinician-scientists as they build momentum as independent investigators, helping bridge the gap between mentored training and full independence. The program is intended to provide resources and structure to establish a focused research direction, generate publishable results, and compete for longer-term research support.

What kind of award mechanism does this opportunity use?

This opportunity uses the NIH grant funding instrument and is associated with the Si2/R00 activity referenced in the program title.

What types of research or program areas does this opportunity cover?

The activity category spans education and health-related research areas, reflecting an emphasis on developing the clinical research workforce while enabling high-impact biomedical studies.

Is this opportunity limited to a single disease area or NIH institute?

No. The breadth of CFDA numbers referenced indicates the program is positioned to support clinical research across many NIH-relevant topics, as long as the project fits NIH priorities and aligns with the program intent of supporting early independent clinical investigators.

What research domains are suggested by the CFDA numbers listed?

The CFDA listings cited span a wide range of NIH mission areas, including environmental health, genomics, sleep disorders, mental health, nursing research, and multiple disease-focused areas such as cancer, cardiovascular disease, lung and blood diseases, arthritis and musculoskeletal conditions, diabetes and kidney disease, neurological disorders, allergy and infectious diseases, child health and human development, and vision research.

How many awards are expected to be made?

The announcement indicates an expected total of about five awards.

Who is eligible to apply?

Eligible applicants include many U.S.-based organization types commonly involved in federal research funding, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), and for-profit organizations (including small businesses and other for-profit entities).

Are government entities eligible to apply?

Yes. Multiple levels of government are listed as eligible, including city/township governments, county governments, state governments, special district governments, and independent school districts.

Are minority-serving and community-oriented institutions included as eligible applicants?

Yes. The opportunity explicitly includes institution types and designations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations.

Are non-U.S. organizations eligible to apply?

No. The announcement states that non-U.S. entities are not eligible to apply.

Are foreign components allowed in this program?

No. Foreign components are not allowed under NIH policy for this program. This includes foreign institutions, non-domestic components of U.S. organizations, and other foreign components as defined by the NIH Grants Policy Statement.

Is cost sharing or matching required?

No. The posting specifies that there is no cost-sharing or matching requirement.

When was this funding opportunity posted?

The FOA was posted and created on April 28, 2015.

What was the closing date for applications?

The original and current closing date listed is August 27, 2015.

When was the opportunity archived?

The archive date listed is September 27, 2015.

Where can applicants find the official full announcement?

The NIH provided an additional information link to the full announcement here: http://grants.nih.gov/grants/guide/pa-files/PAR-15-189.html.

Who should be contacted for technical issues accessing the announcement?

For technical problems accessing the announcement (such as access or linking issues), the posting directs users to contact the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

What kind of career stage does this program aim to support?

Based on the description provided, the program is intended for early-stage, independent clinical researchers at a transition point between mentored training and full independence.

What outcomes is the program designed to help scholars achieve?

The program is described as supporting investigators in establishing a focused research direction, generating publishable results, and strengthening competitiveness for longer-term research support.

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