Opportunity Information: Apply for PAR 16 203
Apply for PAR 16 203
- The HHS-NIH11 in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Lasker Clinical Research Scholars Program (Si2/R00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.172, 93.233, 93.242, 93.279, 93.361, 93.393, 93.394, 93.395, 93.396, 93.398, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.865, 93.867.
- This funding opportunity was created on Apr 18, 2016 and posted on Apr 18, 2016.
- Applicants must submit their applications by Aug 26, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Lasker Clinical Research Scholars Program (Si2/R00), announced under funding opportunity number PAR-16-203 by the National Institutes of Health (HHS-NIH), is a discretionary grant program designed to accelerate the careers of early-stage, independent clinical researchers. Its core purpose is to support promising clinician-scientists at the point where they are ready to run their own research programs, with a structure that intentionally connects two worlds that are often separate: the NIH Intramural Research Program (research conducted within NIH) and the broader extramural community (research conducted at universities, hospitals, and other outside institutions). In practice, it functions as a bridge that gives scholars a substantial period of protected time, resources, and independence to build a clinically oriented research program with the potential for real patient impact.
The program is organized into two phases. Phase 1 places the scholar inside the NIH Intramural Research Program as a tenure-track investigator for a substantial period, typically up to 5 to 7 years, and includes an independent research budget. This phase is meant to provide a stable runway to establish a lab or clinical research team, generate strong data, and mature as an independent investigator while being embedded in the NIH clinical and scientific environment. Phase 2 is a transition option for scholars who are successful in Phase 1. It offers up to 3 additional years of NIH support to continue the scholar's research program at an extramural research facility (such as a university or academic medical center). Alternatively, the scholar may be considered to remain within the intramural program rather than moving outside NIH, giving flexibility for career paths that best fit the individual and the research.
From an administrative and eligibility standpoint, the opportunity is listed as a grant funding instrument and spans NIH-related activity areas connected to health and related public service domains. The eligible applicant types listed are broad and include many kinds of U.S. organizations and government entities, such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3), excluding higher education institutions in those specific categories); for-profit organizations other than small businesses; small businesses; public housing authorities/Indian housing authorities; and Native American tribal governments and tribal organizations. In practical terms, while the program’s intent is clearly centered on individual clinical researchers and their career development, the FOA’s eligibility language reflects the broad range of institutions that might sponsor or host research activities.
In terms of logistics, the FOA was created and posted on April 18, 2016, with an original and current closing date of August 26, 2016. NIH anticipated making about five awards. The listing does not specify an award ceiling amount in the provided data, which suggests applicants would need to consult the full FOA text for detailed budget parameters and any constraints tied to the intramural appointment and the later extramural transition support. The opportunity is associated with multiple CFDA numbers (now generally referred to under the Assistance Listings framework), reflecting the cross-cutting NIH institutes and centers that could be connected to the program’s scope.
Overall, the key takeaway is that this program is meant to identify and invest in a small cohort of highly promising clinical researchers by giving them a rare combination of independence, time, and resources inside NIH first, followed by a supported transition to an outside institution (or the option to remain intramural). The structure is explicitly built to help scholars launch durable, independent clinical research careers while strengthening ties and knowledge flow between the intramural NIH environment and the wider U.S. biomedical research ecosystem.
Frequently Asked Questions (FAQs)
What is the Lasker Clinical Research Scholars Program (Si2/R00)?
The Lasker Clinical Research Scholars Program (Si2/R00) is a discretionary grant program announced by the National Institutes of Health (HHS-NIH) under funding opportunity number PAR-16-203. It is designed to accelerate the careers of early-stage, independent clinical researchers by providing protected time, resources, and independence to build clinically oriented research programs with the potential for patient impact.
What is the main goal of this program?
The core purpose is to support promising clinician-scientists at the stage where they are ready to run their own independent research programs. A defining feature of the program is that it intentionally connects NIH's Intramural Research Program (research within NIH) with the extramural research community (research at universities, hospitals, and other outside institutions).
Which agency is offering this opportunity?
This opportunity is offered by the National Institutes of Health (NIH), within the U.S. Department of Health and Human Services (HHS).
What is the funding opportunity number for this program?
The funding opportunity number is PAR-16-203.
What type of funding instrument is used?
The listing describes this opportunity as a grant funding instrument.
How is the program structured?
The program is organized into two phases. Phase 1 places the scholar within the NIH Intramural Research Program as a tenure-track investigator for a substantial period, and Phase 2 is a transition option that can provide additional NIH support for the scholar to continue the research program at an extramural research facility.
What happens during Phase 1?
In Phase 1, the scholar is placed inside the NIH Intramural Research Program as a tenure-track investigator for a substantial period, typically up to 5 to 7 years. Phase 1 includes an independent research budget and is intended to provide a stable runway for building a lab or clinical research team, generating strong data, and maturing as an independent investigator in the NIH clinical and scientific environment.
How long does Phase 1 last?
Phase 1 typically lasts up to 5 to 7 years.
Does Phase 1 include research funding?
Yes. Phase 1 includes an independent research budget as part of the intramural tenure-track investigator appointment.
What is Phase 2 and who can access it?
Phase 2 is a transition option for scholars who are successful in Phase 1. It provides up to 3 additional years of NIH support to continue the scholar's research program at an extramural research facility, such as a university or academic medical center.
How long does Phase 2 last?
Phase 2 offers up to 3 additional years of NIH support.
Where can Phase 2 be carried out?
Phase 2 can be conducted at an extramural research facility (for example, a university or academic medical center), as described in the listing.
Is moving to an extramural institution required after Phase 1?
No. The listing notes that, alternatively, the scholar may be considered to remain within the intramural program rather than moving outside NIH, providing flexibility depending on career path and research fit.
How does this program bridge intramural and extramural research?
The design places scholars inside NIH first (intramural) with time and resources to establish independence, and then offers a supported transition to an outside institution (extramural) for additional years of research support. This structure is intended to strengthen ties and knowledge flow between NIH intramural science and the broader U.S. biomedical research ecosystem.
Who is the program intended to support?
The program is intended to support early-stage, independent clinical researchers, particularly clinician-scientists who are ready to run their own research programs and whose work is clinically oriented with potential patient impact.
What activity areas does the opportunity cover?
The listing describes the activity areas as NIH-related and connected to health and related public service domains.
What types of applicants are eligible according to the listing?
The eligible applicant types listed are broad and include: state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (501(c)(3) and non-501(c)(3), excluding higher education institutions in those specific categories); for-profit organizations other than small businesses; small businesses; public housing authorities/Indian housing authorities; and Native American tribal governments and tribal organizations.
If the program is centered on individual clinical researchers, why is institutional eligibility listed so broadly?
The listing explains that while the program's intent is centered on individual clinical researchers and career development, the funding opportunity announcement uses broad eligibility language that reflects the wide range of institutions that might sponsor or host research activities.
When was this funding opportunity created and posted?
The listing states the FOA was created and posted on April 18, 2016.
What is the application closing date?
The listing shows an original and current closing date of August 26, 2016.
How many awards did NIH anticipate making?
NIH anticipated making about five awards.
Is there a stated maximum award amount (award ceiling)?
No award ceiling amount is specified in the provided listing data. The description suggests applicants would need to consult the full FOA text for detailed budget parameters and any constraints related to the intramural appointment and the extramural transition support.
Are CFDA/Assistance Listing numbers associated with this opportunity?
Yes. The opportunity is associated with multiple CFDA numbers (now generally referred to under the Assistance Listings framework), reflecting that multiple NIH institutes and centers could be connected to the program's scope.
What is the overall takeaway of this opportunity?
The program is intended to identify and invest in a small cohort of highly promising clinical researchers by providing a rare combination of independence, time, and resources within NIH first, followed by supported transition funding to an outside institution (or the option to remain intramural). The structure is built to help scholars launch durable, independent clinical research careers while strengthening connections between NIH and the extramural research community.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 16 203) also looked into and applied for these:
| Funding Opportunity |
|---|
| Academic Research Enhancement Award (Parent R15) Apply for PA 16 200 Funding Number: PA 16 200 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Mentored Quantitative Research Development Award (Parent K25) Apply for PA 16 194 Funding Number: PA 16 194 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BD2K Mentored Career Development Award in Biomedical Big Data Science for Intramural Investigators (K22) Apply for RFA ES 16 003 Funding Number: RFA ES 16 003 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BD2K Mentored Career Development Award in Biomedical Big Data Science for Clinicians and Doctorally Prepared Scientists (K01) Apply for RFA ES 16 002 Funding Number: RFA ES 16 002 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BD2K Predoctoral Training in Biomedical Big Data Science (T32) Apply for RFA LM 16 002 Funding Number: RFA LM 16 002 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BD2K Open Educational Resources for Skills Development in Biomedical Big Data Science (R25) Apply for RFA HG 16 016 Funding Number: RFA HG 16 016 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $200,000 |
| Change of Grantee Organization (Type 7 Parent) Apply for PA 16 285 Funding Number: PA 16 285 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent) Apply for PA 16 286 Funding Number: PA 16 286 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp) Apply for PA 16 288 Funding Number: PA 16 288 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp) Apply for PA 16 289 Funding Number: PA 16 289 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13) Apply for PA 16 294 Funding Number: PA 16 294 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2016-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]) Apply for PA 16 303 Funding Number: PA 16 303 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship for Students at Institutions With NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 16 305 Funding Number: PA 16 305 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2016-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) Apply for PA 16 302 Funding Number: PA 16 302 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 16 306 Funding Number: PA 16 306 Agency: HHS-NIH11 Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Big Data to Knowledge (BD2K) Community-based Data and Metadata Standards Efforts (R24) Apply for RFA ES 16 010 Funding Number: RFA ES 16 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $250,000 |
| NIH Research Evaluation and Commercialization Hubs (REACH) Awards (U01 Clinical Trial Not Allowed) Apply for RFA OD 19 014 Funding Number: RFA OD 19 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 19 262 Funding Number: PAR 19 262 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 20 167 Funding Number: PAR 20 167 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Emergency Awards: RADx-rad Data Coordination Center (DCC) (U24 Clinical Trial Not Allowed) Apply for RFA OD 20 019 Funding Number: RFA OD 20 019 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $4,000,000 |
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