Opportunity Information: Apply for PAR 08 102
Apply for PAR 08 102
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Leiomyomata Uteri Basic Science, Translational and Clinical Research (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Mar 6, 2008.
- Applicants must submit their applications by May 20, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: County governments Small businesses State governments Private institutions of higher education City or township governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Leiomyomata Uteri Basic Science, Translational and Clinical Research (R01) funding opportunity (PAR 08-102) is an NIH discretionary grant program designed to push uterine fibroid research toward real-world clinical impact. The central aim is to stimulate strong, innovative R01 applications that translate growing knowledge about the molecular and biological mechanisms of leiomyomata uteri (uterine fibroids) into better options for prevention, treatment, and ultimately cure. The announcement explicitly welcomes both new and experienced investigators and emphasizes studies that tackle the complexity of fibroid biology while keeping a clear line of sight to clinical applications that can improve patient outcomes.
This opportunity is sponsored by multiple NIH components, specifically the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Research on Women's Health (ORWH). That mix signals a broad scientific interest in fibroids that spans reproductive health, environmental and gene-environment contributors, and women's health more generally. The FOA highlights three major research lanes: basic science work that advances foundational understanding of fibroid pathogenesis; translational research that bridges lab discoveries to practical interventions; and clinical research that tests or refines approaches in patient-centered contexts. Across these areas, the emphasis is on innovative approaches that can clarify the underlying molecular basis of fibroids and move findings toward clinical improvements.
The mechanism of support is the NIH Research Project Grant (R01), which is the standard NIH award used for investigator-initiated research projects with a defined scope and set of aims. The FOA does not require cost sharing or matching funds, reducing institutional financial barriers and aligning with typical NIH R01 expectations. The activity category is listed under Health, and the CFDA number associated with it is 93.865 (Child Health and Human Development Extramural Research), reflecting the primary institute alignment even though multiple NIH partners are involved.
Eligibility is broad and includes a wide range of domestic U.S. organizations and government entities, such as state governments, county and city/township governments, special district governments, and independent school districts, as well as public and private institutions of higher education. Nonprofit organizations (including those with and without 501(c)(3) status, other than higher education institutions) are eligible, and for-profit organizations are also allowed to apply, including small businesses and other for-profit entities. The announcement also includes eligibility for tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments), as well as public housing authorities/Indian housing authorities. Importantly, the FOA states that foreign institutions are eligible to apply, eligible federal agencies can apply, and faith-based or community-based organizations can apply, underscoring NIH's intent to attract the strongest science regardless of organizational type or geography, as long as the proposal fits the goals of the program and meets NIH requirements.
In terms of timing, the opportunity was posted on March 6, 2008, with an original closing date of May 20, 2010, and a current closing date also listed as May 20, 2010. It was archived on June 20, 2010. While that means this specific announcement is no longer active, the summary is still useful for understanding what NIH sought to fund: rigorous, mechanistically informed, and clinically oriented fibroid research that can convert molecular discoveries into tangible therapeutic strategies.
For applicants or readers seeking the full official text, NIH provided an additional information link to the archived program announcement page (http://grants.nih.gov/grants/guide/pa-files/PAR-08-102.html). NIH also listed contact support through the NIH Office of Extramural Research (OER) web team for access or linking issues, reflecting that the primary administrative entry point for technical problems is the OER webmaster rather than a single scientific program contact listed in the excerpt.
Frequently Asked Questions (FAQs)
What is the Leiomyomata Uteri Basic Science, Translational and Clinical Research (R01) opportunity (PAR 08-102)?
PAR 08-102 is an NIH discretionary funding opportunity that uses the R01 mechanism to support research on leiomyomata uteri (uterine fibroids). The goal is to encourage strong, innovative projects that translate growing knowledge of fibroid molecular and biological mechanisms into better options for prevention, treatment, and ultimately cure.
What is the main purpose of this funding opportunity?
The central aim is to stimulate R01 applications that connect mechanistic understanding of uterine fibroids to real-world clinical impact. The announcement emphasizes research that addresses the complexity of fibroid biology while maintaining a clear line of sight to improvements in patient outcomes.
What types of research does this program support?
The FOA highlights three major research lanes: (1) basic science that advances foundational understanding of fibroid pathogenesis, (2) translational research that bridges laboratory discoveries to practical interventions, and (3) clinical research that tests or refines approaches in patient-centered contexts.
What scientific emphasis does the FOA place on uterine fibroid research?
Across basic, translational, and clinical studies, the FOA emphasizes innovative approaches that clarify the underlying molecular basis of fibroids and move findings toward clinical improvements, including prevention and treatment strategies.
Which NIH components sponsor this opportunity?
This opportunity is sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Research on Women's Health (ORWH).
Why are multiple NIH components involved?
The mix of sponsors signals broad NIH interest in fibroids that spans reproductive health (NICHD), environmental and gene-environment contributors (NIEHS), and women’s health more generally (ORWH).
What grant mechanism is used for this program?
The mechanism of support is the NIH Research Project Grant (R01), NIH’s standard award for investigator-initiated research projects with a defined scope and specific aims.
Does the FOA require cost sharing or matching funds?
No. The FOA states that cost sharing or matching is not required, aligning with typical NIH R01 expectations and reducing institutional financial barriers.
What is the activity category for this opportunity?
The activity category is Health.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.865 (Child Health and Human Development Extramural Research).
Who is eligible to apply?
Eligibility is broad and includes many domestic U.S. organizations and government entities, as well as foreign institutions, eligible federal agencies, and faith-based or community-based organizations, provided NIH requirements are met and the proposal aligns with the program’s goals.
Are state, county, or city governments eligible?
Yes. The FOA lists state governments, county governments, and city/township governments as eligible applicants.
Are special district governments and independent school districts eligible?
Yes. Special district governments and independent school districts are included in the eligibility list.
Are colleges and universities eligible?
Yes. Public and private institutions of higher education are eligible.
Are nonprofit organizations eligible?
Yes. Nonprofits are eligible, including organizations with 501(c)(3) status and those without 501(c)(3) status (other than institutions of higher education).
Are for-profit organizations eligible?
Yes. For-profit organizations are allowed to apply, including small businesses and other for-profit entities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA includes federally recognized tribal governments and tribal organizations (other than federally recognized tribal governments).
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible.
Are foreign institutions eligible to apply?
Yes. The FOA explicitly states that foreign institutions are eligible to apply.
Are federal agencies eligible to apply?
Yes. The FOA states that eligible federal agencies can apply.
Are faith-based or community-based organizations eligible?
Yes. The FOA specifies that faith-based or community-based organizations can apply.
Does this opportunity welcome new investigators?
Yes. The announcement explicitly welcomes both new and experienced investigators.
What are the key characteristics of projects NIH was seeking under this FOA?
Projects were expected to be rigorous and innovative, address the complexity of fibroid biology, and connect molecular and biological insights to clinically meaningful outcomes such as improved prevention and treatment strategies.
When was this opportunity posted?
The opportunity was posted on March 6, 2008.
What were the closing dates for the opportunity?
The original closing date was May 20, 2010, and the current closing date is also listed as May 20, 2010.
Is this funding opportunity still active?
No. It was archived on June 20, 2010, which indicates this specific announcement is no longer active.
If it is archived, why might the FOA still be useful?
Even though it is no longer active, the summary reflects what NIH sought to fund in this area: mechanistically informed uterine fibroid research designed to translate molecular discoveries into tangible clinical strategies.
Where can applicants find the official archived program announcement text?
NIH provided an archived program announcement page at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-102.html
Who should be contacted for technical issues accessing the archived information or linking problems?
NIH listed contact support through the NIH Office of Extramural Research (OER) web team for access or linking issues, indicating the OER webmaster as the administrative entry point for technical problems in this excerpt.
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