Opportunity Information: Apply for PA 16 377
Apply for PA 16 377
- The Department of Health and Human Services, National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Limited Competition: Clinical Research Investigator Supplement (CRIS) for the Maternal Fetal Medicine Units (MFMU) Network and the Neonatal Research Network (NRN) (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on Jul 25, 2016.
- Applicants must submit their applications by Aug 19, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Limited Competition: Clinical Research Investigator Supplement (CRIS) for the Maternal-Fetal Medicine Units (MFMU) Network and the Neonatal Research Network (NRN) is a National Institutes of Health (NIH) administrative supplement opportunity released by the U.S. Department of Health and Human Services. It is designed to add targeted support onto existing network awards rather than fund entirely new, stand-alone grants. In practical terms, the FOA channels additional, relatively modest funding to current MFMU Network and NRN awardees so they can support a promising clinical research scientist working within the structure and priorities of these established multicenter research networks.
The core purpose of the supplement is workforce development focused on clinical and translational research in maternal-fetal medicine and neonatology. The supplement is intended for individuals who already hold a health professional doctoral degree (for example, an MD or equivalent) and who are committed to building a long-term career in laboratory-based research, clinically based research, or patient-oriented research. The FOA emphasizes not just participation in research, but clear potential for the supported individual to grow into an independent investigator. That means the proposed plan should look like a bridge from mentored, structured research activity to a trajectory where the investigator can later compete successfully for independent research funding and lead studies.
This mechanism supports a defined research project lasting two to three years. The project can be structured to combine didactic training (such as coursework, formal instruction, or other organized learning activities) with hands-on research activity conducted in a laboratory setting or through clinical/patient-related research. The intent is not to provide generic training funds, but to support a specialized project that simultaneously advances a real research question and functions as a strong development platform for the investigator. The research itself is expected to have intrinsic scientific importance, meaning it should stand on its own as a meaningful contribution to the field, while also serving as a suitable vehicle for accelerating the investigator’s development, productivity, and independence.
Because it is a limited competition administrative supplement, the opportunity is tied to the MFMU and NRN UG1 network ecosystem. The expectation is that the work will leverage the strengths of these networks, such as their collaborative clinical research environments, established protocols, multicenter patient populations, and experienced research leadership. Supplements like this typically fit best when the investigator’s project is well aligned with network goals and can benefit from the network’s infrastructure, data resources, clinical sites, and mentoring environment.
From a funding and scale perspective, the FOA lists an award ceiling of $50,000 and anticipates making about four awards. That ceiling signals a focused supplement intended to meaningfully support an investigator’s research development activities, but not at the scale of a full research project grant. The Funding Opportunity Number is PA-16-377, it is categorized as a discretionary grant opportunity, and it falls under CFDA 93.865. The original posting dates in the source indicate it was created on July 25, 2016 with an original closing date of August 19, 2016, reflecting that this was a time-bound supplement competition tied to the parent awards active at that time.
Eligibility, as presented in the listing, is broad in the general sense and includes many types of domestic organizations such as various levels of government, public and private institutions of higher education, certain tribal governments and organizations, nonprofits (with and without 501(c)(3) status), for-profit entities other than small businesses, and small businesses, with an additional note to consult the FOA text for specific clarifications. In reality, the key limiting factor is the “limited competition” aspect: the supplement is meant to go to existing MFMU Network and NRN (UG1) awardees, meaning the applicant organization typically must already hold the relevant parent network award to be in a position to request the supplement.
Overall, this FOA is best understood as a targeted NIH investment in the next generation of clinical research leadership within two major perinatal and neonatal research networks. It aims to pair a well-defined, scientifically valuable project with structured career development so that an outstanding clinician-scientist can rapidly gain the skills, mentorship, and research track record needed to become an independent investigator contributing to maternal-fetal and neonatal health research.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the Limited Competition: Clinical Research Investigator Supplement (CRIS) for the Maternal-Fetal Medicine Units (MFMU) Network and the Neonatal Research Network (NRN). It is an NIH administrative supplement released by the U.S. Department of Health and Human Services.
Is this a stand-alone grant or an add-on to an existing award?
It is an administrative supplement, meaning it adds targeted support to an existing MFMU Network or NRN UG1 award rather than funding a brand-new, stand-alone grant.
Who is the supplement intended to support?
The supplement is intended to support a promising clinical research scientist working within the structure and priorities of the MFMU Network or NRN.
What is the main goal of the CRIS supplement?
The main goal is workforce development in clinical and translational research in maternal-fetal medicine and neonatology, with an emphasis on helping the supported individual progress toward becoming an independent investigator.
What type of individual is the FOA aiming to develop?
The FOA targets individuals who already hold a health professional doctoral degree (for example, an MD or equivalent) and who are committed to building a long-term research career in laboratory-based research, clinically based research, or patient-oriented research.
Does the supported individual need to show potential for independence?
Yes. The FOA emphasizes clear potential for the investigator to develop into an independent investigator, with a plan that functions as a bridge from mentored work to later competing successfully for independent research funding and leading studies.
How long can the supported project last?
The mechanism supports a defined research project lasting two to three years.
Can the project include training activities?
Yes. The project can combine didactic training (such as coursework or formal instruction) with hands-on research activity conducted in a laboratory or through clinical/patient-related research.
Is this supplement meant to fund general training?
No. The intent is not to provide generic training funds. It is intended to support a specialized project that advances a real research question while also serving as a strong development platform for the investigator.
Does the research project need to be scientifically important on its own?
Yes. The research is expected to have intrinsic scientific importance and stand on its own as a meaningful contribution to the field, while also accelerating the investigator's development, productivity, and independence.
What networks are involved?
The supplement is tied to the MFMU Network and the NRN within the UG1 network ecosystem.
How should the project relate to the MFMU Network or NRN?
The expectation is that the work will leverage network strengths such as collaborative clinical research environments, established protocols, multicenter patient populations, experienced research leadership, infrastructure, data resources, clinical sites, and mentoring.
What is the award ceiling?
The FOA lists an award ceiling of $50,000.
How many awards does NIH anticipate making?
The FOA anticipates making about four awards.
What does the award ceiling suggest about the scale of this funding?
The $50,000 ceiling signals a focused supplement meant to meaningfully support an investigator's research development activities, but not at the scale of a full research project grant.
What is the Funding Opportunity Number?
The Funding Opportunity Number is PA-16-377.
What is the CFDA number for this opportunity?
This opportunity falls under CFDA 93.865.
What type of grant category is this listed as?
It is categorized as a discretionary grant opportunity.
When was this opportunity originally posted, and what was the original closing date?
The source indicates it was created on July 25, 2016, with an original closing date of August 19, 2016, reflecting a time-bound supplement competition tied to parent awards active at that time.
What types of organizations are listed as eligible in the general sense?
The listing presents broad eligibility including many types of domestic organizations such as various levels of government, public and private institutions of higher education, certain tribal governments and organizations, nonprofits (with and without 501(c)(3) status), for-profit entities other than small businesses, and small businesses. The listing also notes to consult the FOA text for specific clarifications.
What is the key limiting factor for eligibility?
The key limiting factor is the limited competition aspect: the supplement is meant to go to existing MFMU Network and NRN (UG1) awardees, so the applicant organization typically must already hold the relevant parent network award to request the supplement.
What research areas does this opportunity focus on?
It focuses on clinical and translational research in maternal-fetal medicine and neonatology, within the context of the MFMU Network and NRN.
What is the overall intent of the NIH investment described in this FOA?
The FOA is described as a targeted investment in the next generation of clinical research leadership within two major perinatal and neonatal research networks, pairing a scientifically valuable project with structured career development to accelerate a clinician-scientist toward independence.
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