Opportunity Information: Apply for RFA AA 14 003

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition Comprehensive Alcohol HIV/AIDS Research Center (P60)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Dec 12, 2013 and posted on Dec 12, 2013.
  • Applicants must submit their applications by Apr 15, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Limited Competition Comprehensive Alcohol HIV/AIDS Research Center (P60) funding opportunity (RFA-AA-14-003) is a National Institutes of Health (NIH) grant program administered through the National Institute on Alcohol Abuse and Alcoholism (NIAAA) that supports a single, large-scale research center focused on the intersection of alcohol use and HIV/AIDS. The core purpose of this announcement is to fund cross-cutting, center-based research that connects multiple projects and shared resources under one coordinated program, with the expectation that the work will generate findings that can realistically be translated into interventions. In practical terms, NIAAA is looking for research that does more than describe problems; it should help drive strategies that reduce HIV infection and transmission, especially where alcohol use plays a meaningful role in risk behavior, prevention uptake, treatment engagement, or health outcomes.

This FOA is a limited competition and is only open to renewal applications from current awardees of the Alcohol and HIV/AIDS Comprehensive Research Center. That restriction is the defining feature of the opportunity: it is not a general open call for new applicants, and it is not intended to create new centers from scratch. Instead, it is designed to continue and strengthen an existing center program that has already been funded, allowing it to extend its research agenda, infrastructure, and collaborative efforts into a new project period. The announcement also makes clear that foreign institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components are not permitted under NIH policy for this FOA.

The scientific emphasis is tied to broader federal HIV research priorities. The FOA points applicants to the FY2013 Trans-NIH Plan for HIV-Related Research as a guide to the highest-priority goals across NIH. That reference signals that the center is expected to align its research themes with widely recognized HIV priorities (for example, prevention, treatment as prevention, addressing comorbidities and co-occurring conditions, and improving outcomes across the HIV care continuum), while making alcohol-related mechanisms and intervention opportunities central to the work. The underlying idea is that alcohol can shape HIV vulnerability and disease outcomes through behavioral pathways (such as increased sexual risk-taking or reduced adherence to prevention and treatment), social and structural pathways (like environments where heavy drinking and HIV risk overlap), and biological or clinical pathways (including impacts on immune function, liver health, medication interactions, and comorbid conditions). A competitive renewal would typically be expected to show a coherent, integrated plan for how its projects collectively address these issues, and how the center structure accelerates progress beyond what isolated projects could accomplish.

From an administrative standpoint, the opportunity is a discretionary grant using the NIH P60 research center mechanism. It was posted on December 12, 2013, with an application due date (original and current) of April 15, 2014, and it was archived on May 16, 2014. NIAAA anticipated making one award, with an estimated total funding amount of $2,000,000 and an award ceiling of $2,000,000. The Catalog of Federal Domestic Assistance (CFDA) number listed is 93.273 (Alcohol Research Programs). Cost sharing or matching is not required, which is typical for many NIH research grants where the expectation is that the awarded funds cover the proposed scope of work according to NIH cost principles and the approved budget.

Overall, this is best understood as a continuation investment in a single established alcohol and HIV/AIDS research center, with NIAAA using the renewal competition to ensure that the center remains scientifically strong, aligned with NIH-wide HIV priorities, and focused on research that can be translated into real-world interventions to reduce HIV transmission and improve outcomes for people at risk for or living with HIV. For applicants, the key challenge is demonstrating not only strong individual research projects, but also a convincing center-wide strategy: shared cores or resources that add value, collaboration across disciplines, and a clear pathway from research findings to intervention development, testing, or implementation. For anyone needing the full official announcement details, NIH provided an additional information link on the NIH grants website, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact.

Frequently Asked Questions (FAQs)

What is the Limited Competition Comprehensive Alcohol HIV/AIDS Research Center (P60) opportunity?

It is an NIH funding opportunity (RFA-AA-14-003) administered by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to support a single, large-scale, coordinated research center focused on the intersection of alcohol use and HIV/AIDS. The grant uses the NIH P60 research center mechanism.

What is the main purpose of this funding opportunity?

The main purpose is to fund cross-cutting, center-based research that links multiple projects and shared resources under one coordinated program, with the expectation that results can realistically be translated into interventions. The intent is to support research that helps drive strategies to reduce HIV infection and transmission where alcohol meaningfully affects risk, prevention uptake, treatment engagement, or health outcomes.

Is this an open competition for new applicants?

No. This is a limited competition and is only open to renewal applications from current awardees of the Alcohol and HIV/AIDS Comprehensive Research Center. It is not a general open call and is not designed to create new centers from scratch.

Who is eligible to apply?

Only current awardees of the Alcohol and HIV/AIDS Comprehensive Research Center are eligible to apply, and only for a renewal application under this limited competition.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply under this funding opportunity.

Are non-U.S. components of U.S. organizations eligible?

No. The announcement states that non-U.S. components of U.S. organizations are not eligible.

Are foreign components allowed in the proposed work?

No. Foreign components are not permitted under NIH policy for this FOA.

How many awards did NIAAA anticipate making?

NIAAA anticipated making one award.

What is the estimated total funding amount and award ceiling?

The estimated total funding amount is $2,000,000, and the award ceiling is also $2,000,000.

What grant mechanism is used for this program?

This opportunity uses the NIH P60 research center mechanism (a research center grant), designed to support multiple integrated projects and shared resources within a coordinated center program.

What does “center-based” research mean in this FOA?

In this context, center-based research means a coordinated program made up of multiple projects and shared cores/resources that are intentionally connected. The center structure is expected to accelerate progress beyond what separate, isolated projects could accomplish, through collaboration, shared infrastructure, and an integrated scientific plan.

What kinds of research are emphasized?

The FOA emphasizes research on how alcohol use intersects with HIV/AIDS in ways that matter for prevention, transmission, treatment engagement, and health outcomes. It also emphasizes work that can move beyond describing problems to generating findings that can be translated into interventions.

Does the FOA prioritize translation to interventions?

Yes. A central expectation is that the center’s work will generate findings that can realistically be translated into interventions, including development, testing, or implementation pathways that could reduce HIV transmission and improve outcomes.

How is alcohol expected to relate to HIV risk and outcomes in the research supported by this center?

The FOA frames alcohol as influencing HIV vulnerability and disease outcomes through multiple pathways, including behavioral pathways (for example, increased sexual risk-taking or reduced adherence to prevention and treatment), social/structural pathways (for example, environments where heavy drinking and HIV risk overlap), and biological/clinical pathways (for example, impacts on immune function, liver health, medication interactions, and comorbid conditions).

What federal HIV research priorities should the center align with?

The FOA points applicants to the FY2013 Trans-NIH Plan for HIV-Related Research as a guide to the highest-priority goals across NIH. This signals that the center should align its themes with NIH-wide HIV priorities while keeping alcohol-related mechanisms and intervention opportunities central.

What are examples of HIV-related priority areas mentioned or implied by the FOA?

Based on the FOA’s description of NIH-wide priorities, examples include prevention, treatment as prevention, addressing comorbidities and co-occurring conditions, and improving outcomes across the HIV care continuum, with alcohol-related drivers and intervention opportunities integrated throughout.

What is the “key challenge” for applicants in this renewal competition?

The key challenge is demonstrating both strong individual research projects and a convincing center-wide strategy, including shared cores/resources that add value, collaboration across disciplines, and a clear pathway from research findings to intervention development, testing, or implementation.

Is cost sharing or matching required?

No. Cost sharing or matching is not required.

What is the CFDA number for this program?

The CFDA number listed is 93.273 (Alcohol Research Programs).

When was this funding opportunity posted, and when was the application due?

It was posted on December 12, 2013. The application due date (original and current) was April 15, 2014.

Is this funding opportunity still active?

No. The FOA was archived on May 16, 2014.

Where can applicants find the full official announcement details?

NIH provided an additional information link on the NIH grants website for the full official announcement details.

Who should be contacted for technical access issues related to the announcement?

Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact.

What does “discretionary grant” mean here?

The opportunity is described as a discretionary grant under the NIH P60 mechanism, meaning it is a competitively awarded federal research grant administered through NIH and NIAAA under the terms and policies that govern NIH extramural funding.

What is the overall intent of using a renewal competition for this center?

The overall intent is to continue and strengthen an already funded center by extending its research agenda, infrastructure, and collaborative efforts into a new project period, while ensuring the center remains scientifically strong, aligned with NIH-wide HIV priorities, and focused on research that can translate into real-world interventions.

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