Opportunity Information: Apply for RFA HL 13 022
Apply for RFA HL 13 022
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition Data Coordinating Center for Cardiothoracic Surgical Trials Network (CTSN) (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research.
- This funding opportunity was created on Mar 28, 2012 and posted on Mar 28, 2012.
- Applicants must submit their applications by Jun 13, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement , are not allowed.
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Opportunity Summary:
This funding opportunity, RFA-HL-13-022, is a National Institutes of Health (NIH) limited competition announcement seeking applications to serve as the Data Coordinating Center (DCC) for the Cardiothoracic Surgical Trials Network (CTSN). It uses the U01 cooperative agreement mechanism, which means the awardee is expected to work closely with NIH staff in a substantial, collaborative partnership rather than operating entirely independently. The overall purpose is to provide the central administrative, data management, and statistical leadership needed to run a coordinated, multi-site clinical trials network focused on cardiothoracic surgery in adults.
The CTSN itself is designed to evaluate surgical interventions and related clinical management strategies that can improve treatment and outcomes for cardiovascular diseases and conditions requiring cardiothoracic surgical care. A key emphasis in the description is not only improving cardiovascular outcomes, but also optimizing postoperative neurologic function, reflecting the reality that neurologic complications are a significant concern in many cardiothoracic procedures and perioperative management pathways. The network is structured so that clinical enrollment and patient-facing trial operations occur at Network Core Clinical Centers, which are competed under a separate FOA (RFA-HL-13-017). In other words, this DCC opportunity is specifically for the centralized coordinating and analytics hub rather than for hospitals or centers primarily proposing to enroll participants.
As the coordinating center, the DCC is expected to maintain and strengthen the infrastructure that allows multiple collaborative surgical trials to be developed, launched, managed, and analyzed across participating sites. In practical terms, that typically includes responsibilities such as protocol development support, statistical design and analysis planning, creation and maintenance of trial databases, data collection standards, data quality monitoring, randomization support where applicable, interim monitoring and reporting, coordination of study committees, meeting logistics, regulatory and trial documentation support, and cross-site communication systems that keep complex multi-center trials aligned. Because CTSN trials are collaborative and may span different surgical procedures and management approaches, the DCC role is central to ensuring consistency, data integrity, and timely decision-making across studies.
Administratively, this is a discretionary health research funding opportunity under CFDA 93.837 (Cardiovascular Diseases Research). Cost sharing or matching is not required. The announcement was posted March 28, 2012, with an application due date of June 13, 2012, and it was later archived on July 14, 2012. Eligibility is limited to U.S.-based applicants: public and state-controlled institutions of higher education and private institutions of higher education are explicitly listed as eligible. Foreign institutions are not eligible, and foreign components of U.S. organizations are not allowed under NIH policy as referenced in the announcement.
The sponsoring agency is NIH (with the heart and lung focus indicated by the HL numbering, commonly associated with the National Heart, Lung, and Blood Institute). The full announcement was made available through the NIH Grants Guide link provided in the source, and NIH’s Office of Extramural Research (OER) offers technical contact points for access or linking issues.
Frequently Asked Questions (FAQs) - RFA-HL-13-022 (CTSN Data Coordinating Center)
What is RFA-HL-13-022?
RFA-HL-13-022 is a National Institutes of Health (NIH) limited competition funding opportunity announcement seeking applications to serve as the Data Coordinating Center (DCC) for the Cardiothoracic Surgical Trials Network (CTSN).
What is being funded under this opportunity?
This opportunity funds a Data Coordinating Center (DCC) that provides centralized administrative, data management, and statistical leadership to support a coordinated, multi-site clinical trials network in adult cardiothoracic surgery.
What is the purpose of the Cardiothoracic Surgical Trials Network (CTSN)?
The CTSN is designed to evaluate surgical interventions and related clinical management strategies aimed at improving treatment and outcomes for cardiovascular diseases and conditions that require cardiothoracic surgical care in adults.
Does CTSN focus only on cardiovascular outcomes?
No. In addition to improving cardiovascular outcomes, CTSN emphasizes optimizing postoperative neurologic function, acknowledging that neurologic complications are a significant concern in many cardiothoracic procedures and perioperative management pathways.
Is this funding opportunity for hospitals or centers that want to enroll patients in trials?
No. This announcement is specifically for the centralized coordinating and analytics hub (the DCC). Clinical enrollment and patient-facing trial operations occur at Network Core Clinical Centers, which are competed under a separate funding opportunity announcement (RFA-HL-13-017).
What NIH award mechanism is used for this opportunity?
The award uses the U01 cooperative agreement mechanism.
What does a U01 cooperative agreement imply about how the project is run?
A U01 cooperative agreement means the awardee is expected to work closely with NIH staff in a substantial, collaborative partnership, rather than operating entirely independently.
What kind of role does the DCC play within CTSN?
The DCC serves as the central administrative, data management, and statistical leadership hub that maintains and strengthens the infrastructure enabling multiple collaborative surgical trials to be developed, launched, managed, and analyzed across participating sites.
What responsibilities are typically included in the DCC scope for CTSN?
Based on the announcement description, typical DCC responsibilities include protocol development support, statistical design and analysis planning, creation and maintenance of trial databases, data collection standards, data quality monitoring, randomization support where applicable, interim monitoring and reporting, coordination of study committees, meeting logistics, regulatory and trial documentation support, and cross-site communication systems.
Why is the DCC considered central to multi-site cardiothoracic surgical trials?
Because trials are collaborative and may span different surgical procedures and management approaches, the DCC helps ensure cross-site consistency, data integrity, and timely decision-making across studies.
Is this opportunity considered a limited competition?
Yes. The announcement is described as an NIH limited competition opportunity.
What is the CFDA number associated with this funding opportunity?
The CFDA number listed is 93.837, which corresponds to Cardiovascular Diseases Research.
Is cost sharing or matching required?
No. The opportunity states that cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is limited to U.S.-based applicants. The announcement explicitly lists eligible applicant types as public and state-controlled institutions of higher education and private institutions of higher education.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible under this announcement.
Are foreign components of U.S. organizations allowed?
No. Foreign components of U.S. organizations are not allowed under NIH policy as referenced in the announcement.
Which agency is sponsoring this opportunity?
The sponsoring agency is the National Institutes of Health (NIH). The HL numbering indicates a heart and lung focus commonly associated with the National Heart, Lung, and Blood Institute.
When was the opportunity posted?
The announcement was posted on March 28, 2012.
What was the application due date?
The application due date was June 13, 2012.
Is the opportunity still open?
No. The announcement was archived on July 14, 2012.
Where can applicants find the full announcement details?
The full announcement was made available through the NIH Grants Guide link referenced in the source information.
Who provides technical assistance for access or linking issues related to the announcement?
NIH's Office of Extramural Research (OER) provides technical contact points for access or linking issues.
Browse more opportunities from the same category: Health
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Previous opportunity: Core Clinical Centers for the Cardiothoracic Surgical Trials Network, CTSN (UM1)
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