Opportunity Information: Apply for RFA DK 12 510
Apply for RFA DK 12 510
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Oct 12, 2012 and posted on Oct 12, 2012.
- Applicants must submit their applications by Dec 19, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $18,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Only institutions with current Data Coordinating Center (DCC) for The Environmental Determinants of Diabetes in the Young (TEDDY) study are eligible to apply. Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4) opportunity (Funding Opportunity Number RFA-DK-12-510) is a National Institutes of Health (NIH) cooperative agreement aimed at continuing the central coordinating infrastructure for the long-running TEDDY consortium, an epidemiological study focused on environmental factors that influence diabetes development in young people. Rather than funding new, stand-alone science projects, this announcement is designed to keep the consortium functioning smoothly by supporting the Data Coordinating Center (DCC) that has been responsible for core study operations since TEDDY began. In practical terms, the grant is about sustaining the backbone systems, processes, and coordination that allow TEDDY to keep collecting high-quality data and biospecimens, maintaining consistent procedures across sites, and making the resulting resources usable for both current protocol-driven analyses and future research by the broader scientific community.
This is a one-time, limited-competition solicitation for a single UC4 application, meaning NIH intends to fund one coordinating center award and restricts eligibility to the institution that is already serving as the TEDDY DCC. The FOA explicitly limits applicants to the current TEDDY DCC and does not allow non-U.S. (foreign) institutions or non-U.S. components of U.S. organizations to apply, although "foreign components" as defined under NIH policy may be included where allowable. No cost sharing or matching is required. The funding instrument is a cooperative agreement (UC4), which typically signals substantial NIH programmatic involvement compared to a standard grant, reflecting the operational and collaborative nature of running a multi-site consortium and managing a complex, shared data and biosample resource.
The core purpose of the DCC under this award is continued support for TEDDY study activities for up to five years, contingent on satisfactory participant recruitment and retention. The DCC is expected to handle comprehensive data and biosample management functions, including standardized acquisition procedures, quality control systems, ongoing management and curation, and mechanisms for dissemination. A key emphasis is ensuring that data and biosamples are not only collected and managed consistently, but also made accessible, including public accessibility, so that TEDDY becomes and remains a durable resource that other researchers can use for hypothesis-based studies later on.
Another central feature is that the DCC must be able to accommodate and support a wide range of research projects that seek to utilize or augment TEDDY data and biosamples. That support role typically implies developing and maintaining processes for data requests, documentation, harmonization, tracking, and governance, as well as managing chain-of-custody and inventory systems for biosamples and ensuring data integrity across time. At the same time, the FOA draws a clear boundary around what is not being funded here: individual hypothesis-driven research studies are not a component of this announcement. The expectation is that the data and biosamples collected through TEDDY will be used to carry out analyses already specified in the TEDDY protocol and to build a publicly available resource that enables future hypothesis-driven work by the research community.
From an administrative standpoint, the opportunity was posted October 12, 2012, with an original and current closing date of December 19, 2012, and an archive date of January 19, 2013. The estimated total funding level is $18,000,000. The activity is listed under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), and the funding activity category is labeled Food and Nutrition Health, aligning with NIH interest in environmental and potentially dietary determinants relevant to diabetes risk. The sponsoring agency is NIH, and the official full announcement was made available through the NIH grants guide at the provided link. Contact assistance for accessing the announcement was routed through the NIH Office of Extramural Research (OER) webmaster.
Frequently Asked Questions (FAQs)
1) What is this funding opportunity?
This opportunity is the "Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)" (Funding Opportunity Number RFA-DK-12-510). It is an NIH cooperative agreement intended to continue the central coordinating infrastructure for the TEDDY consortium.
2) What is the overall purpose of the award?
The purpose is to sustain the Data Coordinating Center (DCC) that serves as the operational backbone of TEDDY. The focus is on keeping the consortium functioning smoothly by supporting core systems, processes, and coordination needed for consistent multi-site study operations, high-quality data and biospecimen collection, and long-term usability of the resulting resources.
3) Is this opportunity intended to fund new research projects?
No. This announcement is not designed to fund new, stand-alone, hypothesis-driven research studies. It supports coordinating and infrastructure functions so TEDDY can continue protocol-driven activities and produce a durable data and biosample resource for future research use.
4) What type of award mechanism is being used?
The mechanism is a cooperative agreement (UC4). This typically indicates substantial NIH programmatic involvement compared to a standard grant, reflecting the collaborative and operational nature of running a large multi-site consortium and managing shared data and biosample resources.
5) How many awards does NIH intend to make?
This is a one-time, limited-competition solicitation for a single UC4 application. NIH intends to fund one coordinating center award.
6) Who is eligible to apply?
Eligibility is restricted to the institution that is already serving as the TEDDY Data Coordinating Center (DCC). The FOA explicitly limits applicants to the current TEDDY DCC.
7) Can foreign (non-U.S.) institutions apply?
No. Non-U.S. (foreign) institutions are not allowed to apply under this announcement.
8) Can non-U.S. components of U.S. organizations apply?
No. Non-U.S. components of U.S. organizations are not allowed to apply.
9) Are any foreign components allowed at all?
Foreign components, as defined under NIH policy, may be included where allowable. This does not change the restriction that the applicant organization itself must be the current TEDDY DCC and must not be a foreign institution or a non-U.S. component of a U.S. organization.
10) Is cost sharing or matching required?
No. The announcement states that no cost sharing or matching is required.
11) What is the period of support?
The award supports continued TEDDY study activities for up to five years, contingent on satisfactory participant recruitment and retention.
12) What are the main responsibilities of the Data Coordinating Center (DCC) under this award?
The DCC is expected to provide comprehensive data and biosample management and coordinating functions. These include standardized acquisition procedures, quality control systems, ongoing management and curation, and mechanisms for dissemination of data and biosamples.
13) What does the FOA emphasize about data and biosample accessibility?
A key emphasis is ensuring that data and biosamples are not only collected and managed consistently, but also made accessible, including public accessibility, so that TEDDY remains a durable resource for the broader scientific community.
14) Does the DCC need to support outside research projects that want to use TEDDY resources?
Yes. The DCC must be able to accommodate and support a wide range of research projects that seek to utilize or augment TEDDY data and biosamples. This generally implies maintaining processes and infrastructure to manage requests and responsible use of the resource.
15) What kinds of support processes are implied for enabling use of TEDDY data and biosamples?
Based on the description, this support role typically includes developing and maintaining processes for data requests, documentation, harmonization, tracking, and governance. It also includes managing chain-of-custody and inventory systems for biosamples and ensuring data integrity over time.
16) What boundary does the FOA set regarding what is not funded?
The FOA draws a clear boundary that individual hypothesis-driven research studies are not a component of this announcement. The expectation is continued protocol-driven analyses specified in the TEDDY protocol and building a publicly available resource that enables future hypothesis-driven research by others.
17) What is the estimated total funding level?
The estimated total funding level is $18,000,000.
18) Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
19) What is the CFDA number associated with this opportunity?
The activity is listed under CFDA 93.847, "Diabetes, Digestive, and Kidney Diseases Extramural Research."
20) How is the funding activity category labeled?
The funding activity category is labeled "Food and Nutrition Health," aligning with NIH interest in environmental and potentially dietary determinants relevant to diabetes risk.
21) When was the opportunity posted, and what were the relevant dates?
The opportunity was posted on October 12, 2012. The original and current closing date was December 19, 2012. The archive date was January 19, 2013.
22) Where was the full announcement made available?
The official full announcement was made available through the NIH grants guide via the provided link in the opportunity materials.
23) Who was listed as a contact for assistance accessing the announcement?
Contact assistance for accessing the announcement was routed through the NIH Office of Extramural Research (OER) webmaster.
24) What is TEDDY in the context of this FOA?
TEDDY is a long-running epidemiological consortium study focused on environmental factors that influence diabetes development in young people. The DCC award supports the central coordinating infrastructure that allows TEDDY to continue collecting and managing data and biospecimens across sites.
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