Opportunity Information: Apply for PAR 13 147
Apply for PAR 13 147
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition Dominantly Inherited Alzheimer Network (U19)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Apr 1, 2013 and posted on Mar 21, 2013.
- Applicants must submit their applications by May 25, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Application is limited to Washington University, DIANs current sponsoring institution. Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
This funding opportunity, PAR 13 147, is a National Institutes of Health (NIH) discretionary grant announcement for a cooperative agreement (U19) focused on continuing the work of the Dominantly Inherited Alzheimer Network (DIAN). The central goal is straightforward: it is a limited competition designed specifically so the existing DIAN investigators can submit a continuation, or renewal, application to keep the DIAN research program running for another five year project cycle. Because this is a cooperative agreement, the project is expected to involve substantial NIH involvement and coordination alongside the awardee, which fits the structure of a large, complex, multisite research network.
Scientifically, the opportunity supports a unique, coordinated research effort studying early onset, autosomal dominant (familial) Alzheimer disease. This form of Alzheimer disease is relatively rare, but it has a major advantage for research: because the genetic cause is inherited in a dominant pattern, researchers can identify individuals who are very likely to develop symptoms and can study biological and clinical changes that happen years before dementia becomes apparent. The FOA emphasizes that insights gained from this inherited form of the disease are expected to inform understanding of the much more common late onset, non familial Alzheimer disease, particularly around the earliest disease processes, biomarkers, progression patterns, and potential windows for intervention.
From a program and application standpoint, this announcement is not open to the general research community. Eligibility is restricted to Washington University, identified as DIANs current sponsoring institution. Foreign (non U.S.) institutions cannot apply, and non U.S. components of U.S. organizations are not eligible to apply; however, foreign components as defined by the NIH Grants Policy Statement are allowed, which aligns with how large networks may include international sites or collaborators under specific NIH rules. The FOA also notes that it is intended not only to support a renewal for another five years, but also to permit resubmission and or revision applications in subsequent years. A key constraint is that revision applications cannot request support beyond the end date of the parent U19 award, meaning any add on changes must fit within the existing overall project period.
Administrative details in the source data include the activity area of health and aging research (CFDA 93.866), no cost sharing or matching requirement, and key dates showing the announcement was posted March 21, 2013, with a closing date of May 25, 2016 (and an archive date of June 25, 2016). The NIH provides an official link to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-13-147.html and points applicants to the NIH Office of Extramural Research (OER) webmaster for technical issues accessing or linking to the notice.
FAQs: NIH PAR-13-147 (U19) - Dominantly Inherited Alzheimer Network (DIAN) Continuation
What is PAR-13-147?
PAR-13-147 is a National Institutes of Health (NIH) discretionary grant announcement for a cooperative agreement using the U19 activity code. It is designed to continue the work of the Dominantly Inherited Alzheimer Network (DIAN).
What is the main purpose of this funding opportunity?
The purpose is to support a limited competition that allows the existing DIAN investigators to submit a continuation (renewal) application so the DIAN research program can continue for another five-year project cycle.
Is this opportunity open to the general research community?
No. This is a limited competition and is not open to the general research community.
Who is eligible to apply?
Eligibility is restricted to Washington University, which is identified as DIAN's current sponsoring institution.
Can foreign (non-U.S.) institutions apply as the applicant organization?
No. Foreign (non-U.S.) institutions are not eligible to apply.
Are non-U.S. components of U.S. organizations eligible to apply?
No. Non-U.S. components of U.S. organizations are not eligible to apply.
Are foreign components allowed at all under this announcement?
Yes. Foreign components, as defined by the NIH Grants Policy Statement, are allowed, which is consistent with how large research networks may include international sites or collaborators under NIH rules.
What type of award mechanism is being used?
The announcement uses a cooperative agreement mechanism (U19).
What does it mean that this is a cooperative agreement?
It means the project is expected to involve substantial NIH involvement and coordination alongside the awardee, which aligns with the management needs of a large, complex, multi-site research network.
What research area does the FOA support?
The FOA supports a coordinated research effort focused on early onset, autosomal dominant (familial) Alzheimer disease, studied through the DIAN network.
Why focus on dominantly inherited (familial) Alzheimer disease?
This form of Alzheimer disease is relatively rare, but it offers a research advantage because the genetic cause is inherited in a dominant pattern. Researchers can identify individuals who are very likely to develop symptoms and study biological and clinical changes years before dementia becomes apparent.
How is this research expected to help with late-onset (non-familial) Alzheimer disease?
The FOA emphasizes that insights from the inherited form of the disease are expected to inform understanding of the more common late-onset Alzheimer disease, particularly regarding early disease processes, biomarkers, progression patterns, and potential windows for intervention.
What is the intended project period for the renewal supported by this announcement?
The announcement is intended to support a renewal for another five years.
Does the FOA allow resubmissions or revisions?
Yes. The FOA indicates it is intended to permit resubmission and/or revision applications in subsequent years.
Is there a limit on what a revision application can request?
Yes. Revision applications cannot request support beyond the end date of the parent U19 award. Any revision must fit within the existing overall project period.
Is cost sharing or matching required?
No. The opportunity indicates there is no cost sharing or matching requirement.
What is the CFDA number associated with this opportunity?
The activity area is listed under CFDA 93.866 (health and aging research).
When was this funding opportunity posted?
The announcement was posted on March 21, 2013.
What is the closing date for this opportunity?
The closing date listed is May 25, 2016.
When was the opportunity archived?
The archive date listed is June 25, 2016.
Where can applicants find the official NIH announcement text?
The NIH provides the official link to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-13-147.html
Who should be contacted for technical issues accessing or linking to the notice?
The announcement points users to the NIH Office of Extramural Research (OER) webmaster for technical issues accessing or linking to the notice.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 13 147) also looked into and applied for these:
| Funding Opportunity |
|---|
| Limited Competition Biomarkers for Older Controls at Risk for Dementia (BIOCARD) Study (U19) Apply for PAR 13 148 Funding Number: PAR 13 148 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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| NIAID Clinical Trial Implementation Grant (R01) Apply for PAR 13 149 Funding Number: PAR 13 149 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIAID Clinical Trial Planning Grant (R34) Apply for PAR 13 150 Funding Number: PAR 13 150 Agency: National Institutes of Health Category: Health Funding Amount: $150,000 |
| NIAID Clinical Trial Implementation Cooperative Agreement (U01) Apply for PAR 13 151 Funding Number: PAR 13 151 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Aging Research Dissertation Awards to Increase Diversity (R36) Apply for PAR 13 152 Funding Number: PAR 13 152 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Development and Characterization of Animal Models for Aging Research (R01) Apply for PA 13 155 Funding Number: PA 13 155 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Development and Characterization of Animal Models for Aging Research (R21) Apply for PA 13 156 Funding Number: PA 13 156 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Using Evidence from Science and Community Practice to Develop Web and other Technology Based Tools for HIV Treatment Service Provider Organizations to Improve Linkage, Retention, and Re Engagement of HIV Positive Persons in Care Apply for CDC RFA PS13 1311 Funding Number: CDC RFA PS13 1311 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
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| Research on Comparative Effectiveness and Implementation of HIV/AIDS and Alcohol Interventions (R01) Apply for RFA AA 13 003 Funding Number: RFA AA 13 003 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Research on Comparative Effectiveness and Implementation of HIV/AIDS and Alcohol Interventions (R21) Apply for RFA AA 13 004 Funding Number: RFA AA 13 004 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Functional Characterization of Oral Cancer Initiating Cells (R01) Apply for RFA DE 14 001 Funding Number: RFA DE 14 001 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Functional Characterization of Oral Cancer Initiating Cells (R21) Apply for RFA DE 14 002 Funding Number: RFA DE 14 002 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| KNOWLEDGE FOR HEALTH II Apply for SOL OAA 13 000048 Funding Number: SOL OAA 13 000048 Agency: Agency for International Development Category: Health Funding Amount: $40,000,000 |
| Using Traditional Foods and Sustainable Ecological Approaches for Health Promotion and Diabetes Prevention in American Indian/Alaska Native (AI/AN) Communities CC RFA DP08 819 Apply for CDC RFA DP13 1317 Funding Number: CDC RFA DP13 1317 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $100,000 |
| Delta Health Care Services Program Apply for RBS01 2012 DHCS Funding Number: RBS01 2012 DHCS Agency: Business and Cooperative Programs Category: Health Funding Amount: Case Dependent |
| Alcohol Use Disorders Treatment, Services, and Recovery Research (R01) Apply for PA 13 160 Funding Number: PA 13 160 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Alcohol Use Disorders Treatment, Services, and Recovery Research (R21) Apply for PA 13 161 Funding Number: PA 13 161 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Alcohol Use Disorders Treatment, Services, and Recovery Research (R03) Apply for PA 13 162 Funding Number: PA 13 162 Agency: National Institutes of Health Category: Health Funding Amount: $50,000 |
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