Opportunity Information: Apply for RFA DK 09 502
Apply for RFA DK 09 502
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for Continuation of the Randomized Intervention for Vesicoureteral Reflux (RIVUR) (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Sep 16, 2009 and posted on Sep 15, 2009.
- Applicants must submit their applications by Nov 18, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,500,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Independent school districts Public and State controlled institutions of higher education For profit organizations other than small businesses Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities City or township governments State governments Private institutions of higher education County governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The funding opportunity titled "Limited Competition for Continuation of the Randomized Intervention for Vesicoureteral Reflux (RIVUR) (U01)" (Funding Opportunity Number RFA-DK-09-502) is a National Institutes of Health (NIH) announcement issued through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its central purpose is to continue the work of the existing RIVUR consortium, a coordinated multi-site clinical research effort focused on children with vesicoureteral reflux. Rather than opening a broad national competition, this is explicitly a limited competition restricted to the organizations already serving as the consortium's five Clinical Coordinating Centers and its single Data Coordinating Center. In practical terms, the announcement is designed to keep the ongoing study infrastructure intact so that enrollment, participant evaluation, and follow-up can proceed without disruption, while maintaining the collaborative, consortium-based model that the project was built around.
The mechanism of support is a cooperative agreement under the U01 activity code. That matters because a U01 is not a typical investigator-initiated grant where the awardee operates largely independently; instead, it is a structured partnership model where NIH anticipates substantial programmatic involvement. The language in the announcement emphasizes that the Clinical Coordinating Centers will continue to work together cooperatively with the already-established Data Coordinating Center, underscoring that the study is meant to function as a unified consortium with shared procedures, coordinated operations, and centralized data management. The Clinical Coordinating Centers are expected to keep enrolling eligible subjects, conducting study evaluations, and completing ongoing follow-up. The Data Coordinating Center role is implied to remain responsible for the core coordinating functions that keep a multi-site randomized study consistent across locations, such as data collection systems, monitoring, analysis planning, and cross-site coordination, though the announcement summary mainly highlights continued cooperation with the existing DCC rather than detailing every operational responsibility.
NIDDK indicated it intended to commit approximately $3.5 million in fiscal year 2010 to support this continuation effort. The anticipated awards were framed as five Clinical Treatment Center grants plus one Data Coordinating Center grant, aligning with the consortium structure already in place. The overall design is therefore one coordinated continuation package: multiple clinical sites responsible for participant-facing study work, plus a single central coordinating entity responsible for integrating data and keeping the study scientifically and operationally aligned across all participating centers.
From an administrative standpoint, the opportunity was categorized as discretionary funding and listed under the CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting NIDDK stewardship even though the scientific topic is pediatric urinary tract and kidney-related disease. No cost sharing or matching requirement was noted. Key dates included a posted date of September 15, 2009, with the original and current closing date both listed as November 18, 2009, and an archive date of December 19, 2009, meaning the announcement is no longer active but remains part of the historical funding record.
Eligibility in the source data includes a broad set of organization types (public and private higher education institutions, nonprofits with or without 501(c)(3) status, for-profit organizations including small businesses, state and local governments, tribal governments and tribal organizations, U.S. territories or possessions, and various designated institution types such as HBCUs, Hispanic-serving institutions, and tribally controlled colleges and universities). However, the defining practical eligibility constraint is the limited-competition nature of the FOA: it specifically invites applications only from the five Clinical Coordinating Centers and the Data Coordinating Center already involved in the RIVUR consortium. So while the general eligibility list is expansive in form, the real pool of applicants is intentionally narrow to the incumbent consortium components.
For applicants and stakeholders seeking the complete official terms, requirements, and application instructions, the announcement referenced the NIH Guide posting (linked in the additional information URL). The contact information provided is routed through the NIH Office of Extramural Research (OER) webmaster addresses for technical access issues, indicating the summary excerpt does not list a scientific or grants management contact person in the text provided. Overall, the opportunity is best understood as a continuation and maintenance funding vehicle: it is aimed at sustaining an ongoing randomized intervention study in children with vesicoureteral reflux by ensuring the existing clinical sites and the coordinating center can keep enrolling participants, collecting outcomes, and working under a single coordinated consortium framework with NIH involvement through the U01 cooperative agreement structure.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "Limited Competition for Continuation of the Randomized Intervention for Vesicoureteral Reflux (RIVUR) (U01)" and the Funding Opportunity Number is RFA-DK-09-502.
Which agency and NIH institute issued this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity issued through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What is the main purpose of this funding opportunity?
The central purpose is to continue the work of the existing Randomized Intervention for Vesicoureteral Reflux (RIVUR) consortium, which is a coordinated multi-site clinical research effort focused on children with vesicoureteral reflux. The intent is to keep the ongoing study infrastructure intact so enrollment, participant evaluation, and follow-up can continue without disruption.
Is this an open competition?
No. This is explicitly a limited competition. Rather than being open to a broad national applicant pool, it is restricted to the organizations already serving as the RIVUR consortium's five Clinical Coordinating Centers and the single Data Coordinating Center.
Who is eligible to apply in practice?
In practical terms, only the incumbent organizations that serve as the five Clinical Coordinating Centers and the single Data Coordinating Center for the existing RIVUR consortium are invited to apply.
The eligibility list looks broad. Does that mean new organizations can apply?
While the source data includes a broad set of potentially eligible organization types (such as universities, nonprofits, for-profits, governments, and certain designated institution types), the defining constraint is the limited-competition nature of the FOA. The announcement specifically invites applications only from the existing RIVUR consortium components (the five Clinical Coordinating Centers and the Data Coordinating Center).
What funding mechanism is used for this opportunity?
The mechanism of support is a cooperative agreement under the U01 activity code.
What does a U01 cooperative agreement imply about NIH involvement?
A U01 is not the same as a typical investigator-initiated grant where the awardee operates largely independently. It is a structured partnership model in which NIH anticipates substantial programmatic involvement, and the work is carried out in a coordinated, collaborative way across the consortium.
What is the RIVUR consortium expected to do with continuation funding?
The Clinical Coordinating Centers are expected to continue enrolling eligible subjects, conducting study evaluations, and completing ongoing follow-up, while operating under shared procedures and coordinated operations as part of a unified consortium.
How does the Data Coordinating Center fit into this continuation effort?
The announcement emphasizes continued cooperation with the already-established Data Coordinating Center to maintain coordinated, consortium-based operations and centralized data management for the multi-site randomized study. The text provided does not enumerate every operational responsibility, but it indicates the DCC remains central to cross-site coordination.
How many awards were anticipated?
The anticipated awards were framed as a package aligned to the consortium structure: five Clinical Treatment Center (Clinical Coordinating Center) grants plus one Data Coordinating Center grant.
How much funding did NIDDK intend to commit?
NIDDK indicated it intended to commit approximately $3.5 million in fiscal year 2010 to support this continuation effort.
Is cost sharing or matching required?
No cost sharing or matching requirement was noted in the information provided.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
How is the funding categorized?
The opportunity was categorized as discretionary funding.
What were the key dates for this funding opportunity?
The posted date was September 15, 2009. The original and current closing date were both listed as November 18, 2009. The archive date was December 19, 2009.
Is this funding opportunity still active?
No. Because it has an archive date of December 19, 2009 (and a closing date of November 18, 2009), it is no longer active and is part of the historical funding record.
Where should applicants look for the official application instructions and full requirements?
For the complete official terms, requirements, and application instructions, the announcement referenced the NIH Guide posting (via the additional information URL mentioned in the opportunity summary).
Does the provided summary include a scientific or grants management contact?
No specific scientific or grants management contact person is listed in the text provided. The contact information referenced is routed through NIH Office of Extramural Research (OER) webmaster addresses for technical access issues.
What is the overall goal of using a limited competition for this project?
The limited competition format is designed to maintain continuity of the existing RIVUR study by keeping the established clinical sites and the coordinating center in place, so the randomized intervention study can continue enrollment, data collection, and follow-up under the existing consortium framework.
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