Opportunity Information: Apply for RFA AA 16 007

  • The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of CoFASP (Collaboration on Fetal alcohol Spectrum Disorders Prevalence) Diagnostic Classifications (Collaborative U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273,.
  • This funding opportunity was created on Jan 28, 2016 and posted on Jan 28, 2016.
  • Applicants must submit their applications by Apr 10, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education.
Apply for RFA AA 16 007

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Opportunity Summary:

The funding opportunity titled "Limited Competition for the Continuation of CoFASP (Collaboration on Fetal Alcohol Spectrum Disorders Prevalence) Diagnostic Classifications (Collaborative U01)" is a National Institutes of Health (NIH) cooperative agreement notice focused on extending ongoing work within the existing CoFASP network. It is explicitly a limited competition, meaning it is not broadly open to new groups; instead, it invites applications only from projects that were already funded under the Collaboration on Fetal Alcohol Spectrum Disorders (FASD) Prevalence (CoFASP). The intent is to keep a previously established research collaboration moving forward rather than starting a new initiative from scratch.

At its core, the FOA is aimed at giving current CoFASP teams additional time and support to continue developing, refining, and applying a standardized diagnostic system for evaluating children affected by FASD. The emphasis on "diagnostic classifications" reflects a key challenge in FASD research and public health practice: clinical presentations can vary widely, and differences in diagnostic approaches can make it difficult to compare findings across sites, studies, or populations. By supporting follow-up work that advances a shared diagnostic framework, the program is designed to improve consistency in how clinical characteristics are assessed and documented, which in turn strengthens the reliability of prevalence estimates.

A major program goal is to improve the ability to establish prevalence rates of FASD by ensuring that participating sites use a common diagnostic approach when identifying and characterizing cases. Standardization is important for prevalence studies because the estimated rate of a condition can change significantly depending on how cases are defined, what criteria are applied, and how assessments are performed. This continuation opportunity therefore supports the broader CoFASP mission: generating stronger, more comparable evidence about how common FASD is in the populations being studied, while also deepening the clinical understanding of the disorder in affected children.

The award mechanism is a U01 cooperative agreement, which signals that NIH expects substantial scientific or programmatic involvement during the project period, beyond what is typical for a standard research grant. In practice, this usually means the funded teams work closely with NIH program staff and with each other, follow shared protocols or milestones, and participate in coordinated network activities intended to harmonize methods and outputs across the collaboration.

Administratively, the opportunity is listed as discretionary funding within the health activity category, under CFDA numbers 93.273. Eligible applicants include public and state-controlled institutions of higher education as well as private institutions of higher education, but because the FOA is limited competition, eligibility is functionally restricted to those institutions already participating as CoFASP-funded projects. The sponsoring agency is within the U.S. Department of Health and Human Services, specifically NIH (listed as HHS-NIH11 in the source data). The FOA number is RFA-AA-16-007, and the posting and creation dates are both January 28, 2016, with an application closing date of April 10, 2016.

In terms of funding scale, the opportunity lists an award ceiling of $250,000 and anticipates making about two awards. Taken together, that suggests a relatively targeted continuation effort intended to support a small number of existing teams in completing additional follow-up activities tied directly to diagnostic system development and its use in prevalence-related research. The overall thrust is continuity, standardization, and improved measurement: extending CoFASP work so that diagnostic classifications for FASD are applied more consistently, clinical characterization is strengthened, and prevalence estimates become more credible and comparable across participating sites.

FAQs: Limited Competition for the Continuation of CoFASP (Collaboration on Fetal Alcohol Spectrum Disorders Prevalence) Diagnostic Classifications (Collaborative U01)

What is the title of this funding opportunity?

The opportunity is titled "Limited Competition for the Continuation of CoFASP (Collaboration on Fetal Alcohol Spectrum Disorders Prevalence) Diagnostic Classifications (Collaborative U01)."

What is the FOA number?

The FOA number listed is RFA-AA-16-007.

Which agency is sponsoring this opportunity?

The sponsoring agency is the National Institutes of Health (NIH), within the U.S. Department of Health and Human Services (HHS). The source data also lists the agency as HHS-NIH11.

What kind of grant mechanism is being used?

This is a U01 cooperative agreement.

What does a U01 cooperative agreement imply for how the project will run?

A U01 cooperative agreement indicates that NIH expects substantial scientific or programmatic involvement during the project period. Based on the description provided, this typically means funded teams work closely with NIH program staff and with each other, participate in coordinated network activities, and follow shared protocols and/or milestones to harmonize methods and outputs across the collaboration.

Is this opportunity open to new applicants that were not part of CoFASP?

No. This is explicitly a limited competition. Applications are invited only from projects that were already funded under the Collaboration on Fetal Alcohol Spectrum Disorders (FASD) Prevalence (CoFASP). The intent is to extend existing CoFASP work rather than start a new initiative.

What is the main purpose of this continuation funding?

The main purpose is to provide additional time and support for current CoFASP teams to continue developing, refining, and applying a standardized diagnostic system for evaluating children affected by fetal alcohol spectrum disorders (FASD).

What is meant by "diagnostic classifications" in this FOA?

"Diagnostic classifications" refers to the effort to advance a shared, standardized diagnostic framework for assessing and documenting clinical characteristics of children affected by FASD, so that participating sites can evaluate cases in a more consistent way.

Why is standardization of FASD diagnosis emphasized?

The FOA emphasizes standardization because FASD clinical presentations can vary widely, and differences in diagnostic approaches can make it difficult to compare findings across sites, studies, or populations. A common diagnostic approach helps improve consistency in assessment and documentation.

How does this continuation work support FASD prevalence research?

The continuation supports prevalence research by strengthening the ability to establish prevalence rates of FASD through use of a common diagnostic approach across participating sites. Since prevalence estimates can change depending on how cases are defined and assessed, harmonized criteria and procedures make estimates more credible and comparable.

What broader mission of CoFASP does this FOA support?

It supports CoFASP's broader mission of generating stronger, more comparable evidence about how common FASD is in the populations being studied, while also deepening clinical understanding of the disorder in affected children.

Who is eligible to apply (by organization type)?

Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.

Who is eligible to apply in practice given the limited competition?

Although the eligible applicant categories include certain higher-education institutions, the FOA is functionally restricted to institutions already participating as CoFASP-funded projects.

What is the activity category for this opportunity?

The opportunity is listed under the health activity category.

Is this funding described as discretionary?

Yes. It is listed as discretionary funding.

What CFDA number is associated with this opportunity?

The CFDA number provided is 93.273.

What is the award ceiling?

The opportunity lists an award ceiling of $250,000.

How many awards are anticipated?

Approximately two awards are anticipated.

Does the funding scale suggest a broad national competition?

No. The combination of a limited competition and an anticipated two awards suggests a targeted continuation effort to support a small number of existing teams.

What is the posting date for the FOA?

The posting date is January 28, 2016.

What is the creation date for the FOA listing?

The creation date is also January 28, 2016.

What is the application closing date?

The application closing date is April 10, 2016.

Is the goal to start new research sites or maintain an existing network?

The goal is to maintain and extend an existing network. The FOA is designed to keep the previously established CoFASP collaboration moving forward rather than launching a new initiative from scratch.

What are the expected collaborative features of the continuation effort?

Based on the cooperative agreement structure and the description provided, the continuation effort is expected to include coordinated network activities, close interaction with NIH program staff, and harmonization of methods and outputs across participating teams.

What is the central theme of the continuation opportunity in plain terms?

Continuity, standardization, and improved measurement: extending CoFASP work so that diagnostic classifications for FASD are applied more consistently, clinical characterization is strengthened, and prevalence estimates become more credible and comparable across participating sites.

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