Opportunity Information: Apply for RFA DK 15 501
Apply for RFA DK 15 501
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of Look AHEAD (Action for Health in Diabetes) Clinical Centers (Collaborative U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Mar 26, 2015 and posted on Mar 26, 2015.
- Applicants must submit their applications by Jun 1, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 15 candidate(s).
- Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following This FOA is limited to the current awardees of the Look AHEAD Clinical Centers (CCs). Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The funding opportunity RFA-DK-15-501, titled "Limited Competition for the Continuation of Look AHEAD (Action for Health in Diabetes) Clinical Centers (Collaborative U01)," is a National Institutes of Health (NIH) announcement that supports the continued operation of the existing Look AHEAD Clinical Centers through a cooperative agreement mechanism (U01). It is explicitly a limited competition, meaning it is not open to new institutions or teams outside the established Look AHEAD Consortium. The central aim is to extend the study by funding an additional five years of follow-up for participants who are already enrolled, allowing the consortium to continue monitoring long-term outcomes in this well-characterized cohort.
The opportunity uses the cooperative agreement model, which typically indicates substantial NIH programmatic involvement during the project period compared with a standard research grant. In practical terms, this mechanism is designed for large, multi-site efforts where coordination, shared protocols, and consistent data collection across centers are essential. The activity category is listed under health, with relevance to diabetes and related conditions, and it is administered under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning it with the NIH institute mission area that includes diabetes and metabolic disease research.
The purpose of the funding is narrowly focused: it is meant to maintain the infrastructure and operations necessary for continued follow-up of all currently enrolled Look AHEAD participants for five more years. This implies ongoing participant contact, clinical or outcomes assessments as required by the protocol, retention efforts, collection of longitudinal data, and adherence to consortium-wide procedures so that results remain comparable across sites and over time. The announcement also clarifies the broader program structure by pointing out that a related FOA, RFA-DK-15-502, will support the continuation of the Look AHEAD Biostatistics Research Center. That detail signals a coordinated, two-part continuation plan: clinical centers continue participant follow-up while the biostatistics center continues to manage statistical leadership and likely supports data coordination and analytic oversight, helping ensure consistency and scientific integrity across the network.
In terms of eligibility, the FOA is restricted to the current awardees of the Look AHEAD Clinical Centers. While the general eligible applicant categories listed include private and public/state-controlled institutions of higher education, the controlling eligibility requirement is that applicants must already be funded Look AHEAD Clinical Centers. The announcement also includes firm restrictions against foreign participation: non-U.S. entities are not eligible, non-U.S. components of U.S. organizations are not eligible, and foreign components (as NIH defines them) are not allowed. There is no cost sharing or matching requirement, so applicants are not required to commit non-federal matching funds as a condition of the award.
From an administrative standpoint, the FOA was posted on March 26, 2015, with an application due date of June 1, 2015. The expected number of awards is 15, which is consistent with a multi-center consortium structure where multiple clinical sites receive coordinated awards under a shared research framework. The opportunity was archived on July 2, 2015, reflecting that it was a time-limited solicitation intended specifically to fund a continuation period rather than to launch a new, broadly competed research program.
For additional details, NIH provided an official announcement link hosted on the NIH grants site, and general technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster email. Overall, the grant is best understood as a continuity and follow-up funding action: it preserves an established clinical research network so the Look AHEAD cohort can be observed for an additional five years, while a companion funding action supports the biostatistics and coordinating functions needed to manage the consortium-wide data and analyses.
Frequently Asked Questions (FAQs)
What is the funding opportunity RFA-DK-15-501?
RFA-DK-15-501 is an NIH funding opportunity titled "Limited Competition for the Continuation of Look AHEAD (Action for Health in Diabetes) Clinical Centers (Collaborative U01)." It supports the continued operation of the existing Look AHEAD Clinical Centers through a cooperative agreement (U01) mechanism.
What is the main purpose of this opportunity?
The purpose is narrowly focused on maintaining the infrastructure and operations needed to continue follow-up of all currently enrolled Look AHEAD participants for an additional five years. This extended follow-up is intended to support ongoing monitoring of long-term outcomes in an established cohort.
Is this opportunity open to new applicants or new institutions?
No. This is an explicit limited competition and is not open to new institutions or teams outside the established Look AHEAD Consortium. Eligibility is restricted to current awardees of the Look AHEAD Clinical Centers.
What funding mechanism is used, and what does it mean?
The opportunity uses a cooperative agreement mechanism (U01). In practical terms, this model is typically used for large, multi-site efforts where coordination, shared protocols, and consistent data collection across centers are essential, and where NIH has substantial programmatic involvement during the project period compared with a standard research grant.
How long is the continuation period supported by this FOA?
The FOA supports an additional five years of follow-up for participants who are already enrolled in the Look AHEAD study.
What kinds of activities are expected to be supported?
The funding is intended to maintain the clinical center infrastructure and operations necessary for continued participant follow-up, which implies activities such as ongoing participant contact, required clinical or outcomes assessments per protocol, retention efforts, longitudinal data collection, and adherence to consortium-wide procedures to ensure comparability across sites and over time.
What is the research area or activity category for this opportunity?
The activity category is listed under health, with relevance to diabetes and related conditions, consistent with the Look AHEAD program focus.
What is CFDA 93.847 and how does it relate to this FOA?
This opportunity is administered under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning it with the NIH institute mission area that includes diabetes and metabolic disease research.
Who is eligible to apply?
Eligibility is restricted to current awardees of the Look AHEAD Clinical Centers. While general applicant categories can include private and public/state-controlled institutions of higher education, the controlling eligibility requirement is being an existing, currently funded Look AHEAD Clinical Center awardee.
Are foreign organizations or foreign components allowed to participate?
No. The FOA includes firm restrictions: non-U.S. entities are not eligible, non-U.S. components of U.S. organizations are not eligible, and foreign components (as NIH defines them) are not allowed.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement, meaning applicants are not required to commit non-federal matching funds as a condition of the award.
How many awards were expected under this announcement?
The expected number of awards is 15, consistent with a multi-center consortium structure where multiple clinical sites receive coordinated awards under a shared research framework.
What is the relationship between RFA-DK-15-501 and RFA-DK-15-502?
RFA-DK-15-501 supports continuation of the Look AHEAD Clinical Centers, while a related FOA, RFA-DK-15-502, supports continuation of the Look AHEAD Biostatistics Research Center. Together, they reflect a coordinated continuation plan: clinical centers continue participant follow-up and the biostatistics center continues statistical leadership and likely supports data coordination and analytic oversight.
When was this FOA posted, and when were applications due?
The FOA was posted on March 26, 2015, and the application due date was June 1, 2015.
Is this opportunity still active?
No. The opportunity was archived on July 2, 2015, indicating it was a time-limited solicitation intended to fund a specific continuation period rather than launch a new, broadly competed research program.
Where can applicants find the official announcement?
NIH provided an official announcement link hosted on the NIH grants site for this FOA.
Who should be contacted for technical access issues related to the announcement?
General technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster email.
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| Funding Opportunity |
|---|
| Limited Competition for the Continuation of Look AHEAD (Action for Health in Diabetes) Biostatistics Research Center (Collaborative U01) Apply for RFA DK 15 502 Funding Number: RFA DK 15 502 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) Apply for PAR 15 161 Funding Number: PAR 15 161 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Pilot and Feasibility Clinical Research Grants in Urologic Disorders (R21) Apply for PAR 15 162 Funding Number: PAR 15 162 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| New Directions in Hematology Research (SHINE II) (R01) Apply for PAS 15 168 Funding Number: PAS 15 168 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) Apply for PA 15 169 Funding Number: PA 15 169 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Pilot and Feasibility Clinical Trials in Diabetes, and Endocrine and Metabolic Diseases (R21) Apply for PA 15 176 Funding Number: PA 15 176 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Interdisciplinary Training in Bioinformatics and Diabetes, Obesity and Metabolic Disease (T32) Apply for PAR 15 182 Funding Number: PAR 15 182 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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| Implementation of the Animal Feed Regulatory Program Standards (AFRPS) (U18) Apply for RFA FD 15 021 Funding Number: RFA FD 15 021 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $750,000 |
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| Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases (R01) Apply for RFA DK 15 017 Funding Number: RFA DK 15 017 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| NIDDK Centers for Diabetes Translation Research (P30) Apply for RFA DK 15 003 Funding Number: RFA DK 15 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Expanding Course Offerings for State and Local Regulators in the Integrated Food Safety System (U18) Apply for RFA FD 15 039 Funding Number: RFA FD 15 039 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| A Community Research Resource of Microbiome Derived Factors Modulating Host Physiology in Obesity, Digestive and Liver Diseases, and Nutrition (R24) Apply for RFA DK 15 012 Funding Number: RFA DK 15 012 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Exploratory Studies for Delineating Microbiome Host Interactions in Obesity, Digestive and Liver Diseases and Nutrition (R21) Apply for RFA DK 15 013 Funding Number: RFA DK 15 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
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