Limited Competition for the Continuation of the Consortium for Radiologic Imaging Studies in Polycystic Kidney Disease (CRISP) (U01) | Apply Online

Opportunity Summary:

This funding opportunity, RFA DK 10 501, is a limited competition from the National Institutes of Health (NIH), specifically the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), to support the continuation of the Consortium for Radiologic Imaging Studies in Polycystic Kidney Disease (CRISP). It is designed to keep a long-running, prospective observational study in polycystic kidney disease (PKD) moving forward by supporting the same established network of clinical sites and the central coordinating center that already built, maintained, and can still access the CRISP participant cohort and its associated imaging and clinical data. Because CRISP is a specialized longitudinal study with a well characterized participant group, the announcement limits eligibility to the institutions that previously received an award under CRISP II, ensuring continuity of follow-up, consistent methods, and reliable access to prior study infrastructure and records.

The main scientific goal is straightforward: continue follow-up of the existing CRISP participants, who are described as highly motivated and well characterized, and preserve the value of the long-term dataset by extending observation over time. A second major goal is to maintain CRISP as a platform for informative ancillary studies, meaning add-on or companion projects that can leverage the established cohort, imaging protocols, and data systems to answer additional PKD-related questions without having to recreate an entire consortium from scratch. In practical terms, the opportunity is about sustaining the clinical and imaging pipeline, maintaining data quality and coordination across sites, and enabling new analyses and sub-studies that build on the original CRISP investment.

The award mechanism is an NIH cooperative agreement (U01). That matters because a U01 is typically used when the NIH expects to have substantial programmatic involvement during the project, such as participation in steering or oversight activities, coordination requirements across multiple sites, and close collaboration on scientific and operational decisions. This is consistent with a multi-center consortium that relies on standardized imaging and data management processes and needs strong coordination between clinical centers and a central Data Coordinating and Imaging Analysis Center (DCIAC).

Funding is planned at about $1.5 million total in Fiscal Year 2011 to support four awards in total: three participating clinical centers plus one DCIAC. The budget guidance states that an applicant may request up to $225,000 per year in direct costs, for a project period of up to five years. Cost sharing or matching is not required. The announcement lists the funding instrument as discretionary and categorizes the activity under health, with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

Eligibility is intentionally narrow. While the general applicant types referenced include public and state-controlled institutions of higher education and private institutions of higher education, the controlling eligibility restriction is that only institutions that received an award under CRISP II may apply. This aligns with the stated rationale for the limited competition: only the existing CRISP sites and the DCIAC are positioned to continue follow-up seamlessly because they retain access to the cohort, the prospective observational data, and the established operational infrastructure. For leadership, the opportunity allows any qualified individuals with the appropriate skills, knowledge, and resources to serve as Project Director/Principal Investigator (PD/PI), and it reiterates NIH-wide encouragement for individuals from underrepresented racial and ethnic groups and individuals with disabilities to apply.

Applications must follow the U01 format constraints, including a Research Strategy section limited to 12 pages total, with tables, graphs, figures, diagrams, and charts counted within that limit. Key dates included in the listing are a posted and creation date of March 17, 2010, with an original and current closing date of June 30, 2010, and an archive date of July 31, 2010. The full announcement is referenced through the NIH Grants Guide link, and the contact listed for access or linking issues is the NIH Office of Extramural Research (OER) webmaster.

Browse more business programs for Kidney Disease Research

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Food and Nutrition Health

Next opportunity: US Nuclear Regulatory Commission Research Conference Grant and Cooperative Agreement Program

Previous opportunity: ENVIRONMENTAL MONITORING RESEARCH SUPPORT RELATED TO QUAGGA MUSSELS IN LAKES MEAD MOHAVE

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for RFA DK 10 501

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (RFA DK 10 501) also looked into and applied for these:

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "RFA DK 10 501", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.