Opportunity Information: Apply for RFA DK 13 502

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the Drug Induced Liver Injury Network Data Coordinating Center DILIN DCC(U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Dec 12, 2012 and posted on Dec 12, 2012.
  • Applicants must submit their applications by Feb 27, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,170,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Only institutions with the current Data Coordinating Center (DCC) for the Drug Induced Liver Injury Network are eligible to apply. Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

This grant opportunity (RFA-DK-13-502) is a National Institutes of Health (NIH) limited-competition cooperative agreement (U01) intended to provide continued support for the Data Coordinating Center (DCC) of the Drug Induced Liver Injury Network (DILIN). DILIN focuses on drug-induced liver injury, a complex and often difficult-to-diagnose category of liver disease in which liver damage can be caused by prescription drugs as well as nutritional supplements and herbal products. Because the clinical signs and patterns of injury can vary widely and can resemble many other liver conditions, the network relies on consistent data collection, careful case characterization, and centralized coordination to support reliable research findings. The DCC is the core infrastructure that enables that coordination by organizing network operations and ensuring that data from multiple sources can be managed and analyzed in a standardized way.

The award mechanism is a cooperative agreement, which generally indicates substantial NIH program involvement in the conduct of the project compared with a typical research grant. The announcement anticipates a single award, with an estimated total funding level of about $1,170,000. The activity category is listed under health (with the CFDA number 93.847, associated with Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting NIH institute alignment with liver and digestive disease research priorities. There is no cost sharing or matching requirement, meaning the applicant institution is not expected to contribute a mandatory financial match as a condition of receiving the award.

Eligibility is highly restricted. Only the institution that already serves as the current DILIN Data Coordinating Center is allowed to apply, which is what makes this a limited competition rather than an open solicitation. Foreign institutions are explicitly ineligible, and foreign components (as defined by NIH policy) are not allowed. Non-U.S. components of U.S. organizations are also not eligible. In practice, this means the opportunity is designed specifically as a continuation mechanism to maintain an existing coordinating center that already has the systems, expertise, and established relationships necessary to support the network without interruption.

Key dates place the announcement in late 2012 to early 2013. The opportunity was posted and created on December 12, 2012, with an original and current closing date of February 27, 2013, and an archive date of March 30, 2013. The NIH listing also provides a web link to the full announcement text on the NIH grants site, and contact details for the NIH Office of Extramural Research (OER) webmaster for technical issues accessing or linking to the funding announcement.

Frequently Asked Questions (FAQ)

What is the funding opportunity number for this grant?

The funding opportunity number is RFA-DK-13-502.

Which agency is offering this grant opportunity?

This opportunity is offered by the National Institutes of Health (NIH).

What is the purpose of RFA-DK-13-502?

The purpose of this limited-competition cooperative agreement is to provide continued support for the Data Coordinating Center (DCC) of the Drug Induced Liver Injury Network (DILIN).

What is DILIN?

DILIN is the Drug Induced Liver Injury Network. It focuses on drug-induced liver injury, a complex and often difficult-to-diagnose category of liver disease where liver damage can be caused by prescription drugs as well as nutritional supplements and herbal products.

Why does DILIN require a Data Coordinating Center (DCC)?

Drug-induced liver injury can vary widely in clinical signs and injury patterns and can resemble many other liver conditions. Because of that, DILIN relies on consistent data collection, careful case characterization, and centralized coordination. The DCC provides the core infrastructure to organize network operations and ensure that data from multiple sources can be managed and analyzed in a standardized way.

What type of award mechanism is used?

The award mechanism is a cooperative agreement (U01).

What does a cooperative agreement (U01) imply for NIH involvement?

A cooperative agreement generally indicates substantial NIH program involvement in the conduct of the project compared with a typical research grant.

Is this an open competition?

No. This is a limited-competition opportunity.

Who is eligible to apply?

Eligibility is highly restricted. Only the institution that already serves as the current DILIN Data Coordinating Center is allowed to apply.

Why is eligibility restricted to the current DILIN Data Coordinating Center institution?

Based on the information provided, the opportunity is designed as a continuation mechanism to maintain an existing coordinating center that already has the systems, expertise, and established relationships necessary to support the network without interruption.

Are foreign institutions eligible to apply?

No. Foreign institutions are explicitly ineligible.

Are foreign components allowed under this opportunity?

No. Foreign components (as defined by NIH policy) are not allowed.

Are non-U.S. components of U.S. organizations eligible?

No. Non-U.S. components of U.S. organizations are not eligible.

How many awards does NIH anticipate making under this announcement?

The announcement anticipates a single award.

What is the estimated total funding level for this opportunity?

The estimated total funding level is about $1,170,000.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement, meaning the applicant institution is not expected to contribute a mandatory financial match as a condition of receiving the award.

What is the activity category and how is it classified?

The activity category is listed under health.

What CFDA number is associated with this opportunity?

The CFDA number is 93.847, associated with Diabetes, Digestive, and Kidney Diseases Extramural Research.

When was this funding opportunity posted/created?

The opportunity was posted and created on December 12, 2012.

What is the application closing date?

The original and current closing date is February 27, 2013.

When was this opportunity archived?

The archive date is March 30, 2013.

Where can applicants find the full announcement text?

The NIH listing provides a web link to the full announcement text on the NIH grants site.

Who should be contacted for technical issues related to accessing or linking to the funding announcement?

For technical issues accessing or linking to the funding announcement, the listing provides contact details for the NIH Office of Extramural Research (OER) webmaster.

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