Opportunity Information: Apply for RFA DK 14 509
Apply for RFA DK 14 509
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the Hepatitis B Research Network Immunology Center (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Aug 26, 2014 and posted on Aug 26, 2014.
- Applicants must submit their applications by Nov 25, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $7,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Only the current HBRN awardees are eligible to apply to this FOA.
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Opportunity Summary:
The grant opportunity titled "Limited Competition for the Continuation of the Hepatitis B Research Network Immunology Center (U01)" is a National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) intended to support the ongoing work of the Hepatitis B Research Network (HBRN) Immunology Center. Its central aim is to continue and strengthen a dedicated immunology-focused center that advances translational research on hepatitis B virus (HBV). In practical terms, the FOA emphasizes research that helps move discoveries from basic immunology into clinically relevant understanding and applications, with the broader goal of improving the prevention, treatment, and control of hepatitis B. The scientific focus highlighted in the announcement includes clarifying HBV pathogenesis (how the disease develops and causes harm), better defining the natural history of HBV infection (how infection progresses over time in different people and under different conditions), and developing approaches that can contribute to more effective therapeutic strategies and public health control measures.
This announcement uses the cooperative agreement mechanism (U01), which generally means NIH expects to have substantial scientific or programmatic involvement during the project period rather than functioning strictly as a pass-through funder. Cooperative agreements typically involve active coordination between the awardee and NIH staff around milestones, data sharing expectations, network activities, and other collaborative components, which fits the networked nature of the HBRN program and an immunology center embedded within it.
The opportunity is explicitly described as a limited competition. Eligibility is restricted: only current HBRN awardees are allowed to apply. In other words, this is not an open call to the broader research community; it is designed to continue an existing, established network component by allowing incumbent HBRN-funded groups to compete for continuation funding. The listing notes that additional eligibility clarification is contained in the full FOA text, but the key constraint provided in the source information is that applicants must already be HBRN awardees.
Administratively, the FOA is identified by Funding Opportunity Number RFA-DK-14-509 and was posted on August 26, 2014, with the original and current application closing date both set at November 25, 2014. The archive date is December 26, 2014, which signals that the solicitation is no longer active and is preserved for historical reference. The total estimated funding level is listed as $7,000,000, and the FOA states there is no cost sharing or matching requirement, meaning applicants are not expected to provide institutional matching funds as a condition of the award. The activity is associated with the NIH institute and program space reflected in the CFDA listing 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which commonly supports liver and digestive disease research portfolios.
For applicants and readers needing the authoritative details, the FOA provides an additional information link to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-509.html). Contact information is also provided for technical issues accessing the announcement, directing users to the NIH Office of Extramural Research (OER) webmaster contacts. Overall, the opportunity is best understood as a continuation-focused, network-integrated cooperative agreement to sustain and advance an existing hepatitis B immunology center within the HBRN, with a strong emphasis on translational outcomes and deeper mechanistic understanding that can inform improved HBV management and control.
Frequently Asked Questions (FAQs)
What is the title of this NIH funding opportunity?
The opportunity is titled "Limited Competition for the Continuation of the Hepatitis B Research Network Immunology Center (U01)."
What is the main purpose of this FOA?
The central purpose is to continue and strengthen the Hepatitis B Research Network (HBRN) Immunology Center, with an emphasis on advancing translational research on hepatitis B virus (HBV). The goal is to support research that helps move findings from basic immunology into clinically relevant understanding and applications that can improve prevention, treatment, and control of hepatitis B.
What scientific areas does the announcement emphasize?
The FOA highlights research aimed at clarifying HBV pathogenesis (how disease develops and causes harm), better defining the natural history of HBV infection (how infection progresses over time across different people and conditions), and developing approaches that can contribute to more effective therapeutic strategies and public health control measures.
What does it mean that this opportunity supports "translational" hepatitis B immunology research?
Based on the FOA description, translational research here refers to efforts that connect basic immunology discoveries to clinically relevant understanding and potential applications, ultimately supporting improved HBV prevention, treatment, and control.
What funding mechanism is used for this opportunity?
This FOA uses the cooperative agreement mechanism (U01).
What does a U01 cooperative agreement imply about NIH involvement?
A U01 cooperative agreement generally indicates that NIH expects substantial scientific or programmatic involvement during the project period. The FOA description notes that this often includes active coordination between the awardee and NIH staff around items like milestones, data sharing expectations, and network activities, which aligns with the networked nature of the HBRN program.
Is this an open competition?
No. The opportunity is explicitly described as a limited competition.
Who is eligible to apply?
Eligibility is restricted to current HBRN awardees. This means the call is not open to the broader research community and is intended for incumbent, HBRN-funded groups to compete for continuation funding.
Where can applicants find the authoritative eligibility details?
The provided summary notes that additional eligibility clarification is contained in the full FOA text. The FOA is available via the NIH Grants Guide link included with the announcement.
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-DK-14-509.
When was this FOA posted?
The FOA was posted on August 26, 2014.
What were the application due dates?
The original application closing date and the current application closing date are both listed as November 25, 2014.
Is this funding opportunity still active?
No. The archive date is December 26, 2014, which indicates the solicitation is no longer active and is preserved for historical reference.
What is the estimated total funding level?
The total estimated funding level is listed as $7,000,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement, meaning applicants are not expected to provide institutional matching funds as a condition of the award.
Which NIH program area is this opportunity associated with?
The activity is associated with CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) research portfolio.
Where can I read the full FOA?
The FOA points to the NIH Grants Guide page: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-509.html
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the FOA directs users to the NIH Office of Extramural Research (OER) webmaster contacts.
How should this opportunity be understood in the context of HBRN?
Based on the description provided, this is a continuation-focused, network-integrated cooperative agreement intended to sustain and advance an existing hepatitis B immunology center within the HBRN, with strong emphasis on translational outcomes and deeper mechanistic understanding relevant to improved HBV management and control.
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| Funding Opportunity |
|---|
| Limited Competition for the Continuation of the Hepatitis B Research Network Data Coordination Center (U01) Apply for RFA DK 14 510 Funding Number: RFA DK 14 510 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Type 1 Diabetes Complications IMPACT Award (DP3) Apply for RFA DK 14 017 Funding Number: RFA DK 14 017 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,000,000 |
| Consortium on Beta cell Death and Survival (HIRN CBDS) (UC4) Apply for RFA DK 14 021 Funding Number: RFA DK 14 021 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $900,000 |
| (Re)Building a Kidney Coordinating Center (U01) Apply for RFA DK 14 009 Funding Number: RFA DK 14 009 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,600,000 |
| (Re)Building a Kidney Cells to Organ (UH2/UH3) Apply for RFA DK 14 010 Funding Number: RFA DK 14 010 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Psychosocial and Behavioral Aspects of Bariatric Surgery (R01) Apply for RFA DK 14 026 Funding Number: RFA DK 14 026 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $500,000 |
| Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4) Apply for RFA DK 14 508 Funding Number: RFA DK 14 508 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Innovative Research in HIV in Kidney, Urology and Hematology (R01) Apply for RFA DK 14 020 Funding Number: RFA DK 14 020 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $500,000 |
| Elucidating HIV and HIV treatment Associated Metabolic/Endocrine Dysfunction (R01) Apply for RFA DK 14 023 Funding Number: RFA DK 14 023 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $500,000 |
| Food Specific Molecular Profiles and Biomarkers of Food and Nutrient Intake, and Dietary Exposure (R01) Apply for PAR 15 024 Funding Number: PAR 15 024 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Administrative Supplements for Human Islet Research (Admin Supp) Apply for PA 15 025 Funding Number: PA 15 025 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $100,000 |
| Research on Eosinophil Associated Disorders (R01) Apply for PA 15 027 Funding Number: PA 15 027 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Research on Eosinophil Associated Disorders (R21) Apply for PA 15 028 Funding Number: PA 15 028 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $275,000 |
| Underactive Bladder in Aging (R01) Apply for PA 15 049 Funding Number: PA 15 049 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| USAID Child Blindness Program Apply for PGRD 14 0002 Funding Number: PGRD 14 0002 Agency: Agency for International Development Category: Food and Nutrition Health Funding Amount: $250,000 |
| Developmental Centers for Interdisciplinary Research in Benign Urology (P20) Apply for RFA DK 15 001 Funding Number: RFA DK 15 001 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| George M. OBrien Urology Cooperative Research Centers Program (U54) Apply for RFA DK 15 002 Funding Number: RFA DK 15 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| NIDDK Multi Center Clinical Study Cooperative Agreement (U01) Apply for PAR 15 067 Funding Number: PAR 15 067 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Multi Center Clinical Study Implementation Planning Cooperative Agreements (U34) Apply for PAR 15 068 Funding Number: PAR 15 068 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $225,000 |
| Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) Clinical Centers (Collaborative U01) Apply for RFA DK 15 503 Funding Number: RFA DK 15 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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