Opportunity Information: Apply for RFA DK 14 508

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.945 Assistance Programs for Chronic Disease Prevention and Control.
  • This funding opportunity was created on Sep 30, 2014 and posted on Sep 30, 2014.
  • Applicants must submit their applications by Mar 10, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $14,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following This FOA is a limited competition for continuation of the SEARCH Cohort study, which was previously funded in response to RFA DP 10 001. Only the currently funded SEARCH Data Coordinating Center is eligible to apply.
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Opportunity Summary:

The funding opportunity titled "Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)" (Funding Opportunity Number RFA-DK-14-508) is a National Institutes of Health (NIH) cooperative agreement intended to support the continued operation of the SEARCH for Diabetes in Youth Study. SEARCH is a long running, population-based research effort designed to measure and track how often diabetes occurs in children and adolescents in the United States (incidence), how many youth are living with diabetes at a given time (prevalence), and how diabetes-related health outcomes evolve over time. A central aim of SEARCH is to generate high quality, representative data that can inform public health planning, clinical care strategies, and future research priorities related to diabetes in youth.

This FOA focuses specifically on continuing longitudinal follow-up of an established cohort of youth who have already been recruited into the SEARCH study and followed over time. The continued follow-up is meant to deepen understanding of the clinical course of diabetes that begins in childhood or adolescence, including how the disease progresses, what complications emerge, and which factors may shape outcomes. The announcement highlights both acute and chronic complications, along with mortality, signaling an emphasis on capturing serious near-term events (such as acute metabolic complications) as well as long-term conditions that can develop over years. In addition to clinical outcomes, the FOA calls attention to processes of care and quality of life, meaning the study is also expected to document aspects such as how care is delivered, how consistently recommended care is received, and how living with diabetes affects daily functioning and well-being.

Mechanistically, the award uses a cooperative agreement (UC4) rather than a standard grant mechanism. This typically indicates substantial federal scientific or programmatic involvement in the project, with NIH working collaboratively with the awardee on major elements of the study. The activity category is listed under health, with a connection to food and nutrition and chronic disease prevention and control, reflecting the broader public health significance of youth-onset diabetes and the lifestyle, clinical, and systems-level factors that influence outcomes.

The competition is explicitly limited. Only one award is anticipated, and eligibility is restricted to the currently funded SEARCH Data Coordinating Center that was previously supported under a prior solicitation (RFA DP-10-001). In practical terms, this means the FOA is not open to new applicants or new institutions; it is designed to ensure continuity of the existing national cohort infrastructure, data systems, and analytic capacity that the coordinating center provides. There is no cost sharing or matching requirement noted.

In terms of scale and timing, the FOA was posted on September 30, 2014, with an application due date of March 10, 2015, and an estimated total funding level of $14,000,000. Two CFDA numbers are associated with the opportunity: 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.945 (Assistance Programs for Chronic Disease Prevention and Control). The announcement is archived as of April 10, 2015, indicating it is no longer active but remains available as a reference for the goals and structure of this continuation effort.

Overall, this opportunity is best understood as a continuation award meant to preserve and extend one of the key U.S. surveillance and cohort resources for youth-onset diabetes. By maintaining follow-up of the existing SEARCH cohort, the project aims to deliver ongoing, population-grounded evidence about disease burden, emerging complications, care patterns, and lived experience, all of which are essential for improving outcomes for children and young adults with diabetes.

FAQs: Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)

What is the title of this funding opportunity?

The funding opportunity is titled "Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-DK-14-508.

Which federal agency is offering this opportunity?

This is a National Institutes of Health (NIH) funding opportunity.

What type of award mechanism is being used?

The opportunity uses a cooperative agreement mechanism (UC4), which generally indicates substantial federal scientific or programmatic involvement with the awardee during the project.

What is the overall purpose of this FOA?

The purpose is to support continued operation of the SEARCH for Diabetes in Youth Study by continuing longitudinal follow-up of an established cohort of youth who have already been recruited and followed over time.

What is the SEARCH for Diabetes in Youth Study?

SEARCH is a long-running, population-based research effort designed to measure and track how often diabetes occurs in children and adolescents in the United States (incidence), how many youth are living with diabetes at a given time (prevalence), and how diabetes-related health outcomes evolve over time.

What kinds of data is SEARCH intended to produce?

SEARCH is intended to generate high-quality, representative data that can inform public health planning, clinical care strategies, and future research priorities related to diabetes in youth.

What specific activity does this continuation FOA emphasize?

This FOA emphasizes continued longitudinal follow-up of the existing SEARCH cohort to deepen understanding of the clinical course of diabetes that begins in childhood or adolescence.

What outcomes are highlighted for follow-up?

The FOA highlights acute and chronic complications and mortality, indicating an emphasis on capturing serious near-term events as well as longer-term conditions that can develop over years.

Does the FOA address aspects beyond clinical outcomes?

Yes. The FOA calls attention to processes of care and quality of life, meaning the study is expected to document how care is delivered, how consistently recommended care is received, and how living with diabetes affects daily functioning and well-being.

What does "limited competition" mean for this opportunity?

Competition is explicitly limited: only one award is anticipated, and eligibility is restricted to the currently funded SEARCH Data Coordinating Center that was previously supported under the prior solicitation RFA DP-10-001.

Is this opportunity open to new applicants or institutions?

No. Based on the eligibility restriction described, the FOA is not open to new applicants or new institutions and is designed to ensure continuity of the existing coordinating center infrastructure.

How many awards are expected?

Only one award is anticipated.

Who is eligible to apply?

Eligibility is restricted to the currently funded SEARCH Data Coordinating Center previously supported under RFA DP-10-001.

Is there a cost sharing or matching requirement?

No cost sharing or matching requirement is noted in the provided description.

What is the activity category for this opportunity?

The activity category is listed under health, with a connection to food and nutrition and chronic disease prevention and control.

Why is the coordinating center continuity emphasized?

The FOA is described as designed to preserve continuity of the existing national cohort infrastructure, data systems, and analytic capacity that the SEARCH Data Coordinating Center provides.

When was the FOA posted?

The FOA was posted on September 30, 2014.

What was the application due date?

The application due date was March 10, 2015.

What is the estimated total funding level?

The estimated total funding level is $14,000,000.

What CFDA numbers are associated with this opportunity?

Two CFDA numbers are associated with the opportunity: 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.945 (Assistance Programs for Chronic Disease Prevention and Control).

Is this FOA currently active?

No. The announcement is archived as of April 10, 2015, meaning it is no longer active but remains available as a reference.

What is the main public health significance described in the FOA summary?

The opportunity is framed as preserving and extending a key U.S. surveillance and cohort resource for youth-onset diabetes to provide ongoing, population-grounded evidence about disease burden, emerging complications, care patterns, and lived experience.

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